Identifying genetic markers for skin lymphomas
Genomic biomarkers for cutaneous T-cell Lymphoma
This study is looking at skin cancers called cutaneous T-cell lymphomas to find genetic clues that can help doctors diagnose and treat these conditions earlier and more effectively, especially for patients with specific types like mycosis fungoides and Sezary syndrome.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Sloan-Kettering Inst Can Research NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-10812990 on NIH RePORTER |
What this research studies
This research focuses on understanding cutaneous T-cell lymphomas (CTCL), which are aggressive skin cancers with a high mortality rate. The study aims to identify genomic biomarkers that can help in the early diagnosis and prognosis of CTCL, particularly for subtypes like mycosis fungoides and Sezary syndrome. By analyzing genetic alterations in these tumors, the research seeks to improve diagnostic accuracy and develop targeted therapies, ultimately enhancing patient outcomes. The approach involves detailed genetic analysis and clinical assessments to correlate findings with patient health.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals diagnosed with cutaneous T-cell lymphomas, particularly those experiencing delays in diagnosis or with early-stage disease.
Not a fit: Patients with non-cutaneous forms of lymphoma or those who do not have a confirmed diagnosis of CTCL may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to earlier diagnosis and more effective treatment options for patients with aggressive skin lymphomas.
How similar studies have performed: Previous research has shown promise in identifying genetic markers for other types of cancers, suggesting potential success for this novel approach in CTCL.
Where this research is happening
New York, United States
- Sloan-Kettering Inst Can Research — New York, United States (Active)
Researchers
- Principal investigator: Lim, Megan S. — Sloan-Kettering Inst Can Research
- Study coordinator: Lim, Megan S.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.