Understanding how gene regulation affects cutaneous T cell lymphoma

Who could benefit from this research

What this research studies

This research investigates the role of epigenetic changes, particularly DNA methylation, in cutaneous T cell lymphoma, focusing on Sezary syndrome, a severe form of this cancer. By examining how these changes lead to abnormal gene expression, the study aims to identify potential biomarkers for diagnosis and new therapeutic targets. The research utilizes genomic profiling techniques to analyze the gene expression of malignant T cells, providing insights into the mechanisms of oncogenesis. Patients may contribute to understanding how these epigenetic alterations can influence treatment outcomes.

Why it matters

Where this research is happening

• VA San Diego Healthcare System
  San Diego, United States Active

Researchers

• Principal investigator: Wong, Henry Keung — VA San Diego Healthcare System
• Study coordinator: Wong, Henry Keung

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About this research

1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.