Investigating how Staphylococcus aureus affects skin cancer development
Official title: Role of S.aureus in Cutaneous T Cell Lymphoma Pathogenesis
Funded at New York University School of Medicine · NIH-11072057 · Data updated 2026-11-12
This study is looking at how a common skin bacteria called Staphylococcus aureus might affect the growth of Cutaneous T-cell lymphomas (CTCL), a type of skin cancer, by examining the bacteria found on patients' skin to find new ways to understand and treat the disease.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | New York University School of Medicine NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project start | May 10, 2022 |
| Project end | April 30, 2027 |
| Funding year | 2025 |
| Award (this year) | $544,847 |
| NIH project number | 5R01CA271245-04 |
| Project ID | NIH-11072057 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are patients diagnosed with Cutaneous T-cell lymphoma, particularly those experiencing severe symptoms or recurrent bacterial infections.
✕Less likely to help
Patients with other types of lymphomas or skin conditions unrelated to bacterial infections may not benefit from this research.
What this research studies
This research focuses on Cutaneous T-cell lymphomas (CTCLs), a type of skin cancer characterized by the accumulation of malignant T cells. The study aims to understand the role of Staphylococcus aureus, a common bacterium, in the progression of CTCL by examining bacterial strains found in patients' skin. Researchers will isolate and analyze these bacteria to see how they might influence T cell behavior and contribute to cancer development. By exploring the relationship between bacterial infections and CTCL, the research seeks to uncover new insights into the disease's etiology and potential treatment strategies.
Why it matters
Potential benefit: If successful, this research could lead to new therapeutic approaches for treating Cutaneous T-cell lymphoma by targeting bacterial influences on the disease.
How similar studies have gone: Previous research has indicated a link between Staphylococcus aureus and the severity of CTCL, suggesting that this approach has potential based on earlier findings.
Where this research is happening
-
New York University School of Medicine
New York, United States Active
Researchers
- Principal investigator: Koralov, Sergei Borisovich — New York University School of Medicine
- Study coordinator: Koralov, Sergei Borisovich
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.