Condition

Carcinoma, Hepatocellular clinical trials and research

• 15Clinical trials
• 8Countries

Newest Carcinoma, Hepatocellular clinical trials

All recruiting trials (15)

• Predicting liver failure after major liver surgery using CT measurements and vascular shape changes

  Doctors are testing whether adding vascular deformation mapping to CT measurements can better predict liver failure after removing a large portion of the liver.

  Recruiting at 3 sites Minia University · Minya, Minya Governorate and 2 other locations · NCT07727759

• PF-08634404 alone or with ipilimumab for adults with advanced hepatocellular carcinoma not removable by surgery

  This tests PF-08634404 by itself and together with ipilimumab in adults whose hepatocellular carcinoma is advanced and cannot be removed surgically.

  Recruiting at 60 sites Phase 1/2 Pfizer · Irvine, California and 59 other locations · NCT07227012

• Irpagratinib plus atezolizumab and bevacizumab for advanced hepatocellular carcinoma with FGF19 overexpression

  This trial will test whether adding irpagratinib to atezolizumab and bevacizumab helps people with advanced or unresectable hepatocellular carcinoma whose tumors overexpress FGF19.

  Recruiting Phase 2 Asan Medical Center · Seoul and 2 other locations · NCT07010497

• Multimodal ablation with Tislelizumab, lenvatinib and TACE for unresectable primary liver cancer

  This trial will test whether combining multimodal ablation with Tislelizumab (a PD‑1 antibody), lenvatinib, and TACE helps people with unresectable primary liver cancer.

  Recruiting Shanghai Zhongshan Hospital · Shanghai, Shanghai Municipality · NCT06794073

• Evaluating HLX43 for advanced liver cancer patients who can't tolerate standard treatments

  This study is testing a new treatment called HLX43 for people with advanced liver cancer who can't handle standard therapies to see if it helps them.

  Recruiting Phase 2 Shanghai Henlius Biotech · Hunan, Hunan · NCT06742892

• Evaluating AST-201 for GPC3-positive advanced solid tumors

  This study is testing a new treatment called AST-201 to see if it can help people with advanced solid tumors that have a specific marker called GPC3.

  Recruiting at 4 sites Phase 1 Aptamer Sciences, Inc. · Goyang-si, Gyeonggi-do and 3 other locations · NCT06687941

• Combining Adebrelimab and Apatinib for Liver Cancer Patients at High Risk of Recurrence

  This study is testing if combining two medications, Adebrelimab and Apatinib, can help liver cancer patients who are at high risk of their cancer coming back after surgery.

  Recruiting Phase 2 Qilu Hospital of Shandong University · Jinan, Shandong · NCT06454578

• Reducing dosing frequency of immune checkpoint inhibitors in advanced cancers

  This study is testing if giving immune checkpoint inhibitors less often can still help people with advanced cancers feel better while making treatment easier and cheaper.

  Recruiting Phase 2 National University Hospital, Singapore · Singapore · NCT06422403

• Exploring dosage and effectiveness of HLX10 and HLX04 in liver cancer patients

  This study is testing different doses of two new treatments for liver cancer to see how well they work and if they are safe for patients who haven't had treatment before.

  Recruiting Phase 2 Shanghai Henlius Biotech · Shanghai · NCT06349980

• Comparing ultrasound and biomarker screening for liver cancer in patients with cirrhosis or hepatitis B

  This study is testing whether ultrasound or a blood test is better at finding liver cancer early in people with cirrhosis or chronic hepatitis B.

  Recruiting at 18 sites Phase 4 University of Texas Southwestern Medical Center · Los Angeles, California and 18 other locations · NCT06084234

• Comparing two treatments for small liver cancer in patients with low albumin levels

  This study is testing which treatment, either 90-Yttrium Therasphere or microwave ablation, works better for people with small liver cancer and low albumin levels to see which one helps keep the cancer from getting worse in the first year.

  Recruiting Ochsner Health System · New Orleans, Louisiana · NCT05953961

• Improving early diagnosis of liver cancer in high-risk patients in China

  This study is testing if regular check-ups for liver cancer can help catch the disease earlier in people at high risk due to conditions like chronic hepatitis or cirrhosis in China.

  Recruiting Ruijin Hospital · Shanghai, Shanghai Municipality · NCT05870969

• Comparing Ultrasound and MRI for Early Detection of Liver Cancer

  This study is testing whether a special type of MRI can find liver cancer earlier than the usual ultrasound in patients with cirrhosis.

  Recruiting at 33 sites VA Office of Research and Development · Birmingham, Alabama and 33 other locations · NCT05486572

• Using Tislelizumab after liver treatment for liver cancer

  This study is testing if Tislelizumab can help people with advanced liver cancer live longer and have fewer problems after their initial treatment.

  Recruiting at 2 sites Phase 2 Rutgers, The State University of New Jersey · New Brunswick, New Jersey and 1 other locations · NCT05366829

• Understanding disease and treatment in older adults with liver cancer

  This study is trying to understand how liver cancer affects older adults and what treatments work best for them to help improve their care.

  Recruiting The University of Texas Health Science Center at San Antonio · San Antonio, Texas · NCT03894917

Related topics

Quick answers

How many Carcinoma, Hepatocellular clinical trials are recruiting right now?

15, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 8 countries. The most sites are in China (6 trials), United States (6 trials), South Korea (2 trials), Singapore (1 trial), Egypt (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 6, Phase 1: 1, Phase 4: 1, Phase 1/2: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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