Clinical trial Recruiting at 1 site Observational Ages 18 and up

Understanding disease and treatment in older adults with liver cancer

Official title: Characterizing Disease Biology, Treatment Patterns and Toxicity in Older Adults With Advanced Hepatocellular Carcinoma

Run by The University of Texas Health Science Center at San Antonio · NCT03894917 · Data updated 2026-11-12

This study is trying to understand how liver cancer affects older adults and what treatments work best for them to help improve their care.

More Carcinoma, Hepatocellular trials

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment84 (estimated)
SponsorThe University of Texas Health Science Center at San Antonio
Academic / other
Locations1 site (San Antonio, Texas)
StatusRecruiting
StartedSeptember 13, 2019
Main results expectedDecember 2026
Study endsDecember 2027
Registry record updatedJanuary 8, 2026
Trial IDNCT03894917 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are older adults aged 65 and above with newly diagnosed, unresectable advanced hepatocellular carcinoma.

Probably not a fit

Patients with resectable hepatocellular carcinoma or those who have received prior systemic or locoregional therapy may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to recruit 84 older adults, aged 65 and above, who have been newly diagnosed with unresectable advanced hepatocellular carcinoma (HCC) at the UT Health Cancer Center in San Antonio. It utilizes comprehensive geriatric assessment tools to evaluate the unique disease characteristics and treatment patterns in this population. The study will collect data on treatment toxicities and markers of aging to identify barriers to treatment and risk factors for increased morbidity. The findings will inform the development of personalized treatment algorithms for older adults with HCC.

Why it matters

Potential benefit: If successful, this study could lead to more personalized and effective treatment plans for older adults with hepatocellular carcinoma.

How similar studies have gone: While there have been studies focusing on geriatric assessments in cancer treatment, this specific approach to hepatocellular carcinoma in older adults is relatively novel.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Histologically or radiographically (CT or MRI) confirmed newly diagnosed hepatocellular carcinoma.
* Age 18 years and older.
* Patients with advanced, unresectable HCC as determined by the treating physician.

Exclusion Criteria:

* Patients with resectable HCC who are still candidates for locoregional therapy
* Patients receiving prior systemic or locoregional therapy

Where it's running

  • Mays Cancer Center
    San Antonio, Texas, United States
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.