Clinical trial Recruiting at 1 site Observational Ages 18 and up

Using a special dye to guide surgery for sarcoma removal

Official title: Sarcoma Resection Guided by Intraoperative Indocyanine Green Dye Fluorescence Angiography

Run by Mayo Clinic · NCT06409013 · Data updated 2026-11-12

This study is testing whether a special dye can help surgeons remove sarcomas more accurately by showing them where the cancer ends during surgery.

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment75 (estimated)
SponsorMayo Clinic
Academic / other
Locations1 site (Rochester, Minnesota)
StatusRecruiting
StartedMarch 14, 2024
Main results expectedMarch 30, 2027
Study endsMarch 30, 2027
Registry record updatedAugust 4, 2026
Trial IDNCT06409013 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are patients aged 18 and older with biopsy-proven bone or soft tissue sarcoma who are scheduled for surgical resection.

Probably not a fit

Patients with chronic kidney disease or a history of anaphylaxis to dyes will not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study evaluates the effectiveness of indocyanine green (ICG) dye and fluorescence technology during the surgical resection of bone and soft tissue sarcomas. Patients will receive ICG infusion prior to their scheduled surgery, and their medical records will be reviewed to assess the outcomes. The primary objective is to determine how well ICG can help confirm negative margins after tumor removal, potentially improving surgical precision and patient outcomes.

Why it matters

Potential benefit: If successful, this approach could lead to more effective tumor resections and better long-term outcomes for patients with sarcoma.

How similar studies have gone: Other studies have shown promising results using similar fluorescence-guided techniques in surgical oncology, indicating potential for success in this approach.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients with biopsy-proven bone or soft tissue sarcoma undergoing resection

Exclusion Criteria:

* Chronic kidney disease
* Anaphylaxis to dyes

Where it's running

  • Mayo Clinic in Rochester
    Rochester, Minnesota, United States
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.