Using a special dye to guide surgery for sarcoma removal
Sarcoma Resection Guided by Intraoperative Indocyanine Green Dye Fluorescence Angiography
This study is testing whether a special dye can help surgeons remove sarcomas more accurately by showing them where the cancer ends during surgery.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 50 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Mayo Clinic Academic / other |
| Locations | 1 site (Rochester, Minnesota) |
| Trial ID | NCT06409013 on ClinicalTrials.gov |
What this trial studies
This observational study evaluates the effectiveness of indocyanine green (ICG) dye and fluorescence technology during the surgical resection of bone and soft tissue sarcomas. Patients will receive ICG infusion prior to their scheduled surgery, and their medical records will be reviewed to assess the outcomes. The primary objective is to determine how well ICG can help confirm negative margins after tumor removal, potentially improving surgical precision and patient outcomes.
Who should consider this trial
Good fit: Ideal candidates are patients aged 18 and older with biopsy-proven bone or soft tissue sarcoma who are scheduled for surgical resection.
Not a fit: Patients with chronic kidney disease or a history of anaphylaxis to dyes will not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could lead to more effective tumor resections and better long-term outcomes for patients with sarcoma.
How similar studies have performed: Other studies have shown promising results using similar fluorescence-guided techniques in surgical oncology, indicating potential for success in this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients with biopsy-proven bone or soft tissue sarcoma undergoing resection Exclusion Criteria: * \* Age less than 18 * Chronic kidney disease * Anaphylaxis to dyes
Where this trial is running
Rochester, Minnesota
- Mayo Clinic in Rochester — Rochester, Minnesota, United States (Recruiting)
Study contacts
- Principal investigator: Matthew T. Houdek, M.D. — Mayo Clinic in Rochester
- Study coordinator: Clinical Trials Referral Office
- Email: mayocliniccancerstudies@mayo.edu
- Phone: 855-776-0015
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.