Condition

Bile Duct Cancer clinical trials and research

• 18Clinical trials
• 9Countries

Newest Bile Duct Cancer clinical trials

All recruiting trials (18)

• Tissue adhesive (Glubran®2) to reinforce pancreaticojejunostomy in soft pancreas

  This trial will test whether adding a tissue adhesive glue (Glubran®2) to the pancreatic-jejunal connection reduces postoperative pancreatic leaks in adults with a soft pancreas undergoing pancreaticoduodenectomy.

  Recruiting Minia University · Minya, Minya Governorate · NCT07155525

• Neoadjuvant tislelizumab with SBRT and gemcitabine/platinum chemotherapy for borderline or unresectable hilar bile duct cancer

  This trial will see if precise radiotherapy (SBRT) followed by the PD‑1 drug tislelizumab plus gemcitabine and platinum chemotherapy can shrink tumors enough to allow surgery and improve survival in people with borderline resectable or unresectable hilar cholangiocarcinoma.

  Recruiting Phase 2 Shandong Cancer Hospital and Institute · Jinan, Shandong · NCT07030140

• Registry of digestive tumors in Spain

  This study is collecting information on digestive tumors in adults in Spain to see how to improve diagnosis and treatment for patients.

  Recruiting Spanish Cooperative Group for the Treatment of Digestive Tumours (TTD) · Madrid, Madrid · NCT06711211

• Comparing two methods for examining gastrointestinal lesions

  This study is testing whether a new imaging system for examining gastrointestinal lesions works better than the standard method for people undergoing endoscopic ultrasound.

  Recruiting Orlando Health, Inc. · Orlando, Florida · NCT06340620

• Evaluating eccDNAs as biomarkers for diagnosing biliary stricture

  This study is testing if a new type of DNA found in the blood can help doctors better diagnose patients with unclear bile duct blockages, especially to catch cancer earlier.

  Recruiting at 2 sites Peking University Third Hospital · Beijing, Beijing Municipality and 1 other locations · NCT06277531

• Biliary intraductal radiofrequency ablation added to standard care in unresectable extrahepatic biliary tract cancer

  This trial tests whether adding biliary radiofrequency ablation to standard systemic therapy helps patients with unresectable bile duct cancer see benefits from treatment.

  Recruiting Phase 2 Insel Gruppe AG, University Hospital Bern · Bern and 3 other locations · NCT06274879

• Endoscopic radiofrequency ablation for unresectable bile duct cancer

  This study tests whether adding intraductal radiofrequency ablation to standard chemotherapy and bile duct stenting helps people with unresectable bile duct cancer.

  Recruiting at 9 sites Universitätsklinikum Hamburg-Eppendorf · Berlin and 8 other locations · NCT06175845

• Targeting CEA with CAR-T cells for advanced solid tumors

  This study is testing a new type of CAR-T cell treatment for people with advanced solid tumors to see if it's safe and how well it works.

  Recruiting at 2 sites Phase 1 Chongqing Precision Biotech Co., Ltd · Hangzhou, Zhejiang and 1 other locations · NCT06043466

• Evaluating mutations in solid tumors using liquid biopsy and genome sequencing

  This study is trying to see if a blood test can find important gene changes in patients with advanced solid tumors to help doctors choose the best treatments for them.

  Recruiting Centro di Riferimento Oncologico - Aviano · Aviano, Pordonone · NCT06028724

• Testing a new drug combination for advanced biliary tract cancer

  This study is testing a new combination of drugs to see if it can help people with advanced biliary tract cancer live longer and feel better.

  Recruiting Phase 1/2 National Institutes of Health Clinical Center (CC) · Bethesda, Maryland · NCT05849480

• Combination treatment for advanced bile duct cancer

  This study is testing a new combination treatment for patients with advanced bile duct cancer that can't be surgically removed to see if it helps them feel better and live longer.

  Recruiting Phase 2 Beth Israel Deaconess Medical Center · Boston, Massachusetts · NCT05655949

• Combining PDS01ADC with targeted liver chemotherapy for certain cancers

  This study is testing if a new cancer treatment that combines an immune booster with targeted liver chemotherapy can help people with certain advanced cancers feel better and live longer.

  Recruiting Phase 2 National Institutes of Health Clinical Center (CC) · Bethesda, Maryland · NCT05286814

• Analyzing factors affecting pancreatic tumors and cysts

  This study looks at how different factors affect pancreatic tumors and cysts to help improve treatment options for patients.

  Recruiting Umeå University · Umeå · NCT05155878

• Combining Atezolizumab and Tivozanib for Treating Certain Cancer Types

  This study is testing a new combination of two cancer drugs, Atezolizumab and Tivozanib, to see if they can help people with tough-to-treat cancers like bile duct, gallbladder, breast, and neuroendocrine tumors.

  Recruiting Phase 1/2 University of Florida · Gainesville, Florida · NCT05000294

• Liver transplantation for patients with inoperable bile duct cancer

  This study is testing if liver transplantation can help people with inoperable bile duct cancer live longer and have a better quality of life.

  Recruiting Oslo University Hospital · Oslo · NCT04993131

• Using virtual reality to help manage pain in GI cancer patients

  This study is testing if virtual reality can help people with GI cancer manage their severe abdominal pain better than standard treatments.

  Recruiting Cedars-Sinai Medical Center · Los Angeles, California · NCT04907643

• A resource for collecting cancer data and biospecimens

  This study is creating a resource to collect health information and samples from cancer patients and healthy individuals to help improve cancer prevention and treatment strategies.

  Recruiting at 42 sites University of Nebraska · Greenwood Village, Colorado and 41 other locations · NCT02012699

• Collecting tumor tissue samples from patients undergoing surgery or biopsy for cancer

  This study is collecting tissue samples from cancer patients having surgery or biopsies to see if they can find new ways to treat different types of cancer.

  Recruiting National Institutes of Health Clinical Center (CC) · Bethesda, Maryland · NCT01915225

Related topics

Quick answers

How many Bile Duct Cancer clinical trials are recruiting right now?

18, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 9 countries. The most sites are in United States (8 trials), China (3 trials), Egypt (1 trial), Switzerland (1 trial), Sweden (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 4, Phase 1/2: 2, Phase 1: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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