Comparing two methods for examining gastrointestinal lesions

Randomized Trial of Endoscopic Ultrasound Examination Using EndoSound Vision System vs. Standard Echoendoscope

Not applicable Interventional Orlando Health, Inc. · NCT06340620

This study is testing whether a new imaging system for examining gastrointestinal lesions works better than the standard method for people undergoing endoscopic ultrasound.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment140 (estimated)
Ages18 Years to 100 Years
SexAll
SponsorOrlando Health, Inc. Academic / other
Locations1 site (Orlando, Florida)
Trial IDNCT06340620 on ClinicalTrials.gov

What this trial studies

This trial compares the standard echoendoscope with the newly developed EndoSound Visual System for evaluating lesions in the gastrointestinal tract. Endoscopic ultrasound (EUS) is a key procedure for diagnosing pancreatic and bile duct diseases, and this study aims to assess whether the EndoSound Visual System offers advantages over traditional methods. Participants will be randomly assigned to receive either the standard or the new system during their EUS examination. The goal is to determine which method provides better diagnostic accuracy and patient outcomes.

Who should consider this trial

Good fit: Ideal candidates are adults aged 18 and older who require an EUS examination for various gastrointestinal conditions.

Not a fit: Patients under 18 years old or those unable to consent for the procedure will not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved diagnostic capabilities for patients with pancreatic and gastrointestinal diseases.

How similar studies have performed: While endoscopic ultrasound is a well-established technique, the specific application of the EndoSound Visual System is novel and has not been extensively tested in prior studies.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Age ≥ 18 years
* Any patient undergoing EUS examination for evaluation of the pancreas, bile duct, mediastinal or intraabdominal lymph nodes, or luminal lesions in the esophagus, stomach, duodenum or colon.

Exclusion Criteria:

* Age \< 18 years.
* Unable to obtain consent for the procedure from either the patient or LAR.
* Intrauterine pregnancy.

Where this trial is running

Orlando, Florida

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Pancreatic DiseasePancreatic CancerPancreatic CystGastrointestinal TumorBile Duct DiseasesBile Duct CancerLymph Node DiseaseSubmucosal Tumor of Gastrointestinal Tract
Last reviewed 2026-06-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.