Sponsor or institution
Clinical trials and research at University of Arkansas at Fayetteville
As of November 12, 2026, Find a Trial lists 70 NIH-funded research projects at this institution, with $35.7 million in listed awards. Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 70NIH research projects
NIH-funded research (newest 40 of 70)
Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.
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Native American Tribes Outreach and Education to Improve Food Safety
A tribal-focused program will provide tailored food-safety training and outreach to Native producers and tribal staff to help meet FSMA Produce Safety Rule requirements.
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Modern, shared biomedical research spaces to grow metabolic science at the University of Arkansas
A large NIH grant will create new, collaborative lab spaces at the University of Arkansas to boost metabolic and biomedical research that could improve health in Arkansans.
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Transforming Spatial Proteomics for Nanometer-Scale Protein Mapping
A research project aims to map where proteins are and how they interact inside cells at incredibly tiny scales to better understand cancer biology.
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Robotic hip augmentation for osteoporotic bones with biomechanical planning
A team will test a robotic, computer-guided way to strengthen the hip bone in people with osteoporosis to reduce the risk of fracture.
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Bat behavior and virus shedding linked to spillover risk
This NIH grant explores how bat behavior and virus shedding in wild populations could influence the chance that viruses jump to humans or other animals, with a focus on Kenya and Belize.
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Decoding how genes and environment shape complex traits
This NIH grant would study how genetic differences and environmental factors work together to influence complex traits and diseases using advanced multi-omics in model organisms and natural populations.
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Understanding how gene therapy works over time in Duchenne-related disease
Aiming to learn what affects how long gene therapy lasts and how the body reacts to it in Aran-Duchenne disease.
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Understanding how PKC tweaks Kv7.2 to control neuron signals
A researcher is studying how a specific chemical modification (phosphorylation) changes a neuron potassium channel (Kv7.2) to affect brain excitability and epilepsy risk.
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Understanding how proteins move to cause disease and help design better treatments
This grant studies how proteins change shape and move, using advanced computer simulations, to learn more about diseases and potential therapies.
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Impact of Provider Stress and Health on Medical Decisions in Abdominal Pain Care
This grant studies how provider stress, personal health concerns, and illness-related inflammation may lead to inconsistent care for patients with abdominal pain in emergency departments.
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Mechanobiology of multicellular shape changes in cancer
A scientist team will study how physical forces inside and around cells influence how groups of cells grow and form shapes, with a focus on cancer-related changes.
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How Toll receptors shape skin-like tissues and energy use
This NIH grant explores how Toll receptors help epithelial cells change shape and organize into proper tissue during development, using fruit-fly models and human-relevant biology.
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High-Performance GPU Cluster for Molecular Simulations at Arkansas
A powerful new GPU cluster will be bought and set up at the University of Arkansas to speed up molecular simulations and machine-learning modeling for NIH-funded projects.
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Tunable cortical dynamics across many timescales for awake brains
A broad theory and user-friendly tools to understand how the cortex keeps fast and slow neural activity in balance in awake mice.
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Understanding muscle health in anorexia nervosa and how exercise could help
This grant looks at how anorexia nervosa changes muscle and whether muscle-building exercise could help if started early or after weight loss.
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Understanding how nutrient balance affects energy in aging muscles
Aging adults may lose muscle strength partly because mitochondria don’t work as well, and this project explores how nutrients inside cells influence that process.
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Data Science Core for AI-Driven Biomedical Research
A data science and AI core at the University of Arkansas helps researchers analyze large, complex biomedical data to uncover targets for treatment.
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Imaging and Spectroscopy Core for Metabolic Disease Research
A centralized imaging and spectroscopy facility at the University of Arkansas supports researchers studying how cell and tissue metabolism affects disease, development, and healing.
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Bioenergetics Core fuels cellular energy research
A core facility at a university helps scientists study how cells make and use energy, using live-cell tests and flow cytometry to understand mitochondria and metabolism.
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Administrative Core for a metabolic research center
A new core at the University of Arkansas will coordinate operations for a center studying how cell and tissue metabolism affects disease, development, and repair using advanced imaging, bioenergetics, and data science.
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Arkansas Integrative Metabolic Research Center
A partnership at the University of Arkansas aims to unlock how metabolism works in diseases by building shared research cores and supporting scientists across metabolism-focused biology.
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Metabolic factors in pediatric mitochondrial disorders and organ dysfunction
This project looks at why kids with mitochondrial disorders develop multi-organ problems by studying how energy metabolism and specific molecules affect cells.
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How breast cancer metabolism affects nerve growth in tumors
This project looks at whether changes in breast cancer cell metabolism cause nerves to grow into tumors and help the cancer spread, which could matter for people with breast cancer.
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Mediators of Muscle Rejuvenation with Aging
This research will look at how a key gene (MYC) in muscle cells responds to exercise and whether boosting it can promote muscle health and aging.
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Understanding how aging affects muscle function and how exercise can help
This study is looking at how aging affects muscle strength and whether exercise can help improve it, focusing on a protein called MYC that helps muscles adapt to working out, and it's being tested in mice to find ways to keep our muscles healthy as we get older.
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Genetic factors behind how cells regulate stress responses after transcription
This grant studies how cells decide what to do after making RNA when they’re stressed, using yeast to understand why people vary in stress tolerance and vulnerability.
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Engineered mini-heart models that mimic low-oxygen heart damage
Engineered mini-heart systems recreate the low-oxygen zones that happen during and after a heart attack so researchers can develop treatments to protect heart tissue and help patients recover.
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Investigating heart injury caused by low oxygen levels after a heart attack
This study is looking at how low oxygen levels impact heart tissue after a heart attack, using special systems to mimic those conditions, so we can learn more about how to help patients recover better.
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Understanding what makes gene therapy last
Researchers are looking at genetic and cellular reasons gene therapy can fade or cause changes, aiming to help people with genetic conditions like Duchenne muscular dystrophy.
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How doctor stress, health worries, and short-term illness affect ER care for abdominal pain
This project looks at whether emergency doctors’ stress, concerns about their own health, or short-term inflammation change how they treat people with abdominal pain.
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Tribal Food Safety Alliance: support for Native American growers and food businesses
This program provides culturally tailored training and support to Native American farmers and tribal food businesses to help them meet FDA food-safety rules like the Produce Safety Rule and Preventive Controls for Human Food.
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Robotic system to help with minimally invasive back decompression and lumbar fusion
This project is building a robot with new imaging tools to help surgeons perform minimally invasive decompression and lumbar fusion for people with nerve-compressing back problems.
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How important proteins change shape and work
Using advanced computer simulations, researchers will map how human proteins tied to infection and mood regulation, like the coronavirus spike and serotonin transporter, change shape to help guide future treatments.
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How a chemical switch changes the Kv7.2 nerve channel
This research looks at whether adding a small chemical tag to the Kv7.2 nerve channel changes how it binds helpers and could affect epilepsy in people with Kv7.2-related seizures.
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Understanding how brain activity works across different timescales.
This study is looking at how different parts of the brain work together over short and long periods, using awake mice to learn more about brain activity, which could help us understand and treat brain disorders better.
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Separating cells by how strongly they contract to help understand cancer and heart disease
Researchers separate cells by how strongly they pull and squeeze to find links to breast cancer, cardiovascular disease, and aging.
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How bat behavior affects the risk of viruses jumping to people
Researchers will track bat movements and virus shedding in wild bat populations to learn when and how viruses that can infect people are most likely to spill over.
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Understanding how exercise can rejuvenate aging muscles
This study is looking at how getting older affects our muscles and whether exercise can help improve muscle health by focusing on a special protein called MYC, and it's designed for older adults who want to understand how to keep their muscles strong as they age.
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Investigating how phosphorylation affects neuron channel activity related to epilepsy
This study is looking at how a special part of brain cells, called the Kv7.2 channel, changes when it gets a chemical tweak, and it hopes to find out how this affects signals in the brain, which could help people with epilepsy, especially those with certain genetic changes.
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Understanding how metabolic issues affect multiple organ dysfunction in children with mitochondrial disorders
This study is looking at how problems with tiny energy factories in cells, called mitochondria, can cause serious issues in different organs of children with specific mitochondrial disorders, and it aims to find out how certain substances in the body might be making things worse, so we can improve care for these kids.
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