Understanding how exercise can rejuvenate aging muscles
Mediators of Muscle Rejuvenation with Aging
This study is looking at how getting older affects our muscles and whether exercise can help improve muscle health by focusing on a special protein called MYC, and it's designed for older adults who want to understand how to keep their muscles strong as they age.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Arkansas at Fayetteville NIH-funded |
| Lab location | 1 site (Fayetteville, United States) |
| Project ID | NIH-11137367 on NIH RePORTER |
What this research studies
This research investigates how aging affects muscle function and how exercise can potentially reverse these effects. It focuses on a specific protein, MYC, which is influenced by exercise and plays a crucial role in muscle health. Using a mouse model, the study will analyze how MYC induction and exercise impact muscle cells at a molecular level, including their energy use and genetic changes. The goal is to uncover mechanisms that could lead to improved muscle function in older adults.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults over 21 years old who are experiencing age-related muscle decline.
Not a fit: Patients who are younger than 21 or do not have age-related muscle decline may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for enhancing muscle health and function in older adults, potentially improving their quality of life.
How similar studies have performed: Previous research has shown that exercise can positively impact muscle function in aging populations, suggesting that this approach may yield beneficial results.
Where this research is happening
Fayetteville, United States
- University of Arkansas at Fayetteville — Fayetteville, United States (Active)
Researchers
- Principal investigator: Murach, Kevin — University of Arkansas at Fayetteville
- Study coordinator: Murach, Kevin
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.