Understanding how brain activity works across different timescales.
Official title: Tunable multi-timescale cortical dynamics: fundamental theory and practical tools
Funded at University of Arkansas at Fayetteville · NIH-11159599 · Data updated 2026-11-12
This study is looking at how different parts of the brain work together over short and long periods, using awake mice to learn more about brain activity, which could help us understand and treat brain disorders better.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Arkansas at Fayetteville NIH-funded |
| Lab location | 1 site (Fayetteville, United States) |
| Project start | August 1, 2024 |
| Project end | May 31, 2027 |
| Funding year | 2025 |
| Award (this year) | $328,030 |
| NIH project number | 5R01DA060744-02 |
| Project ID | NIH-11159599 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for participation or benefit from this research would include individuals with brain disorders or those interested in the underlying mechanisms of brain function.
✕Less likely to help
Patients with conditions unrelated to brain function or those not residing in the study area may not receive any benefit from this research.
What this research studies
This research investigates how neural circuits in the cerebral cortex coordinate their activity over various timescales, from quick responses to longer-term memory functions. By developing new theoretical frameworks and analytical tools, the project aims to explore how these timescales are adjusted based on behavioral context. The research will involve testing hypotheses in awake mice to gain insights into the dynamics of brain activity. This could lead to a better understanding of brain disorders and improve treatment strategies.
Why it matters
Potential benefit: If successful, this research could enhance our understanding of brain function and lead to improved treatments for brain disorders.
How similar studies have gone: While the approach of integrating multiple timescales in neural dynamics is innovative, similar research has shown promise in understanding brain function, suggesting potential for success.
Where this research is happening
-
University of Arkansas at Fayetteville
Fayetteville, United States Active
Researchers
- Principal investigator: Shew, Woodrow L. — University of Arkansas at Fayetteville
- Study coordinator: Shew, Woodrow L.
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.