Sponsor or institution
Clinical trials and research at Rosalind Franklin Univ of Medicine & Sci
As of November 12, 2026, Find a Trial lists 45 NIH-funded research projects at this institution, with $17.4 million in listed awards. Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 45NIH research projects
NIH-funded research (newest 40 of 45)
Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.
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Improving Diabetic Foot Ulcer Offloading with User-Friendly Cast Walker Design
A small pilot study to see how different removable cast walker designs affect daily use and healing of diabetic foot ulcers.
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How the liver's ketone production affects muscle loss and recovery in pancreatic cancer
This project looks at whether helping the liver make ketones can prevent muscle wasting and aid recovery for people with pancreatic cancer.
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How the amygdala and social behavior develop during adolescence
Studying how experiences in adolescence shape the brain’s social circuits to help understand and prevent lifelong social difficulties.
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Targeting Vasopressin and Oxytocin Receptors to Treat Anxiety and Fear
Researchers are testing how brain chemical signals related to vasopressin and oxytocin in the BNST region affect fear and anxiety, with the goal of identifying new ways to treat anxiety disorders.
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Role of TAM receptors in humoral immunity and malaria
A doctor-science team is studying how a specific immune pathway (TAM receptors on B cells) affects antibody responses to malaria and whether blocking this pathway could improve immunity.
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Understanding rejection sensitivity and mental health in LGBTQ+ teens
A long-term study follows LGBTQ+ adolescents to see how worries about rejection affect their mood and mental well-being.
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Machine learning finds brainstem cells that control facial movements
A broad study using machine learning and brain cells to map the brainstem circuits that control breathing, eating, speaking, and facial movements, with potential relevance to autism and Rett syndrome.
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How social experiences shape brain development and social behavior
This study looks at how social interactions affect brain circuits and social behavior in people from adolescence to adulthood.
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PNU-120596 for HIV-related thinking and memory problems
This project tests whether PNU-120596, a drug that boosts a brain receptor, can protect the brain and reduce thinking and memory problems in people living with HIV.
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How the brain protein neurexin affects social flexibility and amygdala learning
This project looks at whether changes in the ASD-linked gene neurexin alter brain connections that help people change their social behavior.
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Cell death in lung and blood‑vessel cells during melioidosis
This project looks at whether a type of inflammatory cell death in lung and blood‑vessel cells helps or harms people with melioidosis, a severe bacterial infection.
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Protecting DNA in BRCA-related and advanced cancers
Researchers are looking at how cells protect DNA during replication to help people with BRCA-related or advanced cancers who may develop resistance to treatments like PARP inhibitors.
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What causes Coats plus at the molecular level
Researchers are looking at how problems in a DNA-protecting protein complex lead to the DNA-copying errors that cause Coats plus in affected people.
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How TAM receptors on immune cells affect antibody protection against malaria
Researchers are testing whether blocking a stress-driven pathway in B cells can help people in malaria areas make stronger, longer-lasting antibodies.
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Investigating how a gene affects social behavior and brain function in autism
This study is looking at how a specific gene called neurexin affects social behavior and brain connections in people with Autism Spectrum Disorder, using animal models to help us understand why some individuals may struggle with social interactions.
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Better Medicines for HIV/AIDS
This work aims to create new and safer versions of current HIV/AIDS medicines by targeting specific transporters in the body.
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Understanding the genetic causes of Coats Plus Disease
This study is looking into Coats Plus Disease, a rare genetic condition that causes developmental challenges, to better understand the genetic changes behind it and find new ways to help improve treatment options for those affected.
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Using a new drug to improve brain health in people with HIV-related cognitive issues
This study is looking at a new drug called PNU-120596 to see if it can help protect brain cells and improve thinking skills in people with HIV-related brain issues.
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How oxytocin and vasopressin receptors change brain circuits that drive anxiety
This work looks at whether two brain receptors, oxytocin and vasopressin, change activity in a fear-related brain circuit and could point to new ways to help people with anxiety disorders.
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Investigating how certain enzymes affect recovery from brain injuries and dementia.
This study is looking at how certain enzymes might help the brain heal after a traumatic brain injury and how they could be connected to dementia, with the hope that what we learn could lead to better treatments for both conditions.
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Understanding how certain proteins help transport drugs in the body
This study is looking at how certain proteins help move medications in and out of cells, which could explain why some infections and diseases become resistant to treatment, and the results might help improve therapies for conditions like alcoholism and autism.
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Understanding how RAD51 helps maintain DNA stability in cancer cells
This study looks at how a protein called RAD51 helps keep cancer cells healthy by protecting their DNA during stressful times, which could lead to better treatments for patients, especially those with certain genetic changes like BRCA mutations.
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How worries about rejection affect mental health in LGBTQ+ adolescents and young adults
Researchers will follow sexual minority teens and young adults and use short, real-time smartphone prompts to learn how expecting or feeling rejection links to depression, anxiety, and suicidal thoughts.
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Understanding how social experiences shape brain development during adolescence
This study is looking at how experiences during teenage years shape a part of the brain called the amygdala, which is important for how we interact with others, to help us understand why some people might struggle with social situations later in life.
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Finding a new way to prevent melanoma caused by UV damage
This study is looking at how UV light can harm our DNA and lead to melanoma, a type of skin cancer, and it aims to find new ways to help our bodies repair that damage, especially for people with certain genetic changes in their tumors.
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Understanding how brain networks adapt to sensory inputs
This study looks at how different brain cells in a sea creature respond to the same sensory information to see if their differences are random or important for keeping the brain working well, which could help us understand how our own brains adapt to different situations.
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Targeting specific brain cells for gene delivery and reprogramming
This study is looking at ways to make sure that gene therapies can safely and effectively deliver genetic material to specific brain cells, like astrocytes, without affecting other types of cells, so that treatments for brain conditions can work better and more reliably.
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How certain cell deaths affect infections from a specific bacteria
This study is looking at how a special kind of cell death affects the body’s response to infections from a germ that causes melioidosis, and it aims to find ways to boost the good responses while reducing any harm, which could help improve treatments for people with this condition.
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Transforming brain cells from Parkinson's patients into dopamine-producing neurons
This study is looking at a new way to help people with Parkinson's disease by using their own brain cells to create new neurons that produce dopamine, which could help improve their movement and make treatment more personal and effective.
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Enhancing vaccines for certain bacterial infections in children and the elderly
This study is looking for better ways to help kids and older adults fight off serious infections caused by certain bacteria by figuring out how to boost their immune response and improve vaccines.
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Understanding the genetic causes of Coats Plus Disease
This study is looking into Coats Plus Disease, a rare genetic condition that causes serious developmental issues, to understand how certain genetic changes affect DNA stability and to find new ways to help manage the disease for patients.
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Understanding how calcium channels affect brain function in Alzheimer's disease
This study is looking at how certain channels in brain cells help keep our brain activity balanced, especially in people with Alzheimer's disease, using tiny worms to see how changes in these channels affect brain communication, which could lead to new ways to help improve brain function for patients.
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Creating targeted treatments for HIV/AIDS medications
This study is looking at ways to make HIV treatments safer and more effective by creating new tools that help transport important medications in the body, which could lead to fewer side effects for patients.
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Investigating the impact of switching from menthol to non-menthol cigarettes on heart health markers.
This study is looking at how changing from menthol to non-menthol cigarettes might help reduce inflammation and improve heart health for smokers, and it hopes to share helpful information that could guide decisions about menthol cigarette use.
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Understanding how organelle deficits contribute to Alzheimer's disease
This study is looking at how problems with tiny parts inside our brain cells might contribute to Alzheimer's disease, and it hopes to find new ways to help improve brain health for people with this condition.
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Understanding how certain receptors affect immune responses to malaria
This study is looking at how certain receptors on B cells affect the immune response to malaria in people who get infected multiple times, with the hope of finding ways to help the body fight the disease better.
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Improving the design of removable cast walkers for diabetic foot ulcers
This study is looking at how to make removable cast walkers easier to use for people with diabetic foot ulcers, so they can wear them more often and help their feet heal better.
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Understanding how the brain makes unique decisions
This study is looking at how different parts of the brain help mice make decisions, and by understanding this, we hope to learn why people sometimes choose differently in similar situations.
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How anxiety affects Alzheimer's disease differently in men and women
This study is looking at how anxiety might affect the progression of Alzheimer's disease, especially in women, by examining the brains of male and female mice to understand the connection between anxiety and memory loss.
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Investigating a new treatment for Kaposi's sarcoma using an aptamer
This study is looking at a new treatment using a special drug to help people with HIV who have cancers caused by a virus called KSHV, aiming to find a safe and effective way to fight this virus and improve their health.
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