Understanding how the brain makes unique decisions

Neural circuits for decision making

NIH-funded research Rosalind Franklin Univ of Medicine & Sci · NIH-10828455

This study is looking at how different parts of the brain help mice make decisions, and by understanding this, we hope to learn why people sometimes choose differently in similar situations.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionRosalind Franklin Univ of Medicine & Sci NIH-funded
Lab location1 site (North Chicago, United States)
Project IDNIH-10828455 on NIH RePORTER

What this research studies

This research investigates the neural circuits involved in decision-making, focusing on how individual differences influence choices. By studying mice, the researchers aim to identify specific brain networks, particularly in the cingulate cortex and striatum, that contribute to unique decision-making processes. The study employs advanced techniques such as optogenetics and two-photon imaging to explore how these circuits function and interact. Insights gained from this research could help explain why people make different choices in similar situations.

Who could benefit from this research

Good fit: Ideal candidates for participation or benefit from this research would be individuals experiencing mental health disorders that affect decision-making.

Not a fit: Patients with well-defined decision-making processes and no mental health issues may not receive benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to better understanding and treatment of mental health disorders related to decision-making.

How similar studies have performed: While the exploration of neural circuits in decision-making is ongoing, this specific focus on idiosyncratic decision-making is relatively novel and has not been extensively tested.

Where this research is happening

North Chicago, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Mental health disordersPsychiatric DiseasePsychiatric Disorderpsychological disorderMental disorders
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.