How worries about rejection affect mental health in LGBTQ+ adolescents and young adults

A longitudinal and experience sampling investigation of rejection sensitivity and its role in sexual minority adolescents' mental health

NIH-funded research Rosalind Franklin Univ of Medicine & Sci · NIH-11055351

Researchers will follow sexual minority teens and young adults and use short, real-time smartphone prompts to learn how expecting or feeling rejection links to depression, anxiety, and suicidal thoughts.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionRosalind Franklin Univ of Medicine & Sci NIH-funded
Lab location1 site (North Chicago, United States)
Project IDNIH-11055351 on NIH RePORTER

What this research studies

You would be invited to take part in a multi-year project that follows sexual minority adolescents and young adults and asks them about their feelings and social experiences over time. The team will use regular questionnaires and short, momentary smartphone surveys to capture expectations of rejection, emotions in the moment, and mood symptoms. They will look at how patterns of expecting or perceiving rejection relate to depression, anxiety, and self-harm risk and whether certain supports or coping skills help. Findings aim to clarify what leads to worse mental health and what might protect LGBTQ+ youth.

Who could benefit from this research

Good fit: Sexual minority adolescents and young adults who identify as LGBTQ+, are in the teen to young-adult age range, and are willing to complete repeated surveys and brief smartphone prompts.

Not a fit: People who are not sexual minorities, cannot use a smartphone or prefer not to complete frequent surveys, or who need immediate clinical treatment may not benefit directly from participating.

Why it matters

Potential benefit: If successful, this work could help identify early warning signs and inform ways to prevent or reduce depression and suicidality among LGBTQ+ youth.

How similar studies have performed: Work in adults has linked rejection sensitivity to mental health problems, but longitudinal and real-time (experience sampling) work in adolescents is limited, so this approach is relatively novel for youth.

Where this research is happening

North Chicago, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.