NIH-funded research Career grant

Investigating the impact of switching from menthol to non-menthol cigarettes on heart health markers.

Official title: Effect of Menthol to Non-Menthol Cigarette Switching on Subclinical Inflammatory Biomarkers of Cardiovascular Health: Simulating a Menthol Cigarette Ban

Funded at Rosalind Franklin Univ of Medicine & Sci · NIH-10884362 · Data updated 2026-11-12

This study is looking at how changing from menthol to non-menthol cigarettes might help reduce inflammation and improve heart health for smokers, and it hopes to share helpful information that could guide decisions about menthol cigarette use.

More Cardiovascular Health research and trials

Quick facts

Grant typeCareer grant
Study typeNIH-funded research
Funding institutionRosalind Franklin Univ of Medicine & Sci
NIH-funded
Lab location1 site (North Chicago, United States)
Project startSeptember 1, 2022
Project endJune 30, 2027
Funding year2024
Award (this year)$177,714
NIH project number5K01HL164670-03
Project IDNIH-10884362 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are adult smokers aged 21 and older who currently use menthol cigarettes.

Less likely to help

Patients who do not smoke or who exclusively use non-menthol cigarettes may not benefit from this research.

What this research studies

This research explores how switching from menthol to non-menthol cigarettes affects inflammation and cardiovascular health. It aims to measure specific biomarkers in smokers to understand the potential health benefits of such a switch. By comparing the inflammatory responses of smokers using menthol versus non-menthol cigarettes, the study seeks to provide insights into the cardiovascular risks associated with menthol cigarette use. The findings could inform public health policies regarding menthol cigarette bans.

Why it matters

Potential benefit: If successful, this research could lead to improved cardiovascular health outcomes for smokers who switch from menthol to non-menthol cigarettes.

How similar studies have gone: Previous studies have indicated that switching from menthol to non-menthol cigarettes may reduce health risks, but this specific approach is still being explored.

Where this research is happening

  • Rosalind Franklin Univ of Medicine & Sci
    North Chicago, United States
    Active

Researchers

  • Principal investigator: Jao, Nancy Chia Lei — Rosalind Franklin Univ of Medicine & Sci
  • Study coordinator: Jao, Nancy Chia Lei

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.