Understanding how social experiences shape brain development during adolescence
Parallel maturation of social behaviors and amygdala circuits
['FUNDING_R01'] · ROSALIND FRANKLIN UNIV OF MEDICINE & SCI · NIH-11049532
This study is looking at how experiences during teenage years shape a part of the brain called the amygdala, which is important for how we interact with others, to help us understand why some people might struggle with social situations later in life.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | ROSALIND FRANKLIN UNIV OF MEDICINE & SCI (nih funded) |
| Locations | 1 site (NORTH CHICAGO, UNITED STATES) |
| Trial ID | NIH-11049532 on ClinicalTrials.gov |
What this research studies
This research investigates how experiences during adolescence affect the development of the amygdala, a brain region crucial for social behavior. By examining the connections between the amygdala and other brain areas, the study aims to uncover how these changes can lead to social impairments later in life. The researchers will analyze synaptic and molecular changes that occur during this critical developmental period, focusing on the balance of social motivation and its regulation by the prefrontal cortex. This work could provide insights into the biological underpinnings of social behavior and its dysfunction.
Who could benefit from this research
Good fit: Ideal candidates for this research include adolescents and young adults who have experienced social deprivation or other harmful social experiences.
Not a fit: Patients who are not in the adolescent age range or who have not experienced significant social challenges may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better understanding and interventions for social impairments stemming from adverse experiences during adolescence.
How similar studies have performed: Previous research has shown promising results in understanding the role of the amygdala in social behavior, suggesting that this approach could yield valuable insights.
Where this research is happening
NORTH CHICAGO, UNITED STATES
- ROSALIND FRANKLIN UNIV OF MEDICINE & SCI — NORTH CHICAGO, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: ROSENKRANZ, JEREMY E — ROSALIND FRANKLIN UNIV OF MEDICINE & SCI
- Study coordinator: ROSENKRANZ, JEREMY E
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.