Sponsor or institution
Clinical trials and research at Purdue University
As of November 12, 2026, Find a Trial lists 9 clinical trials run by Purdue University that are recruiting, in United States. By phase: Phase 1/2 (1). There are also 335 NIH-funded research projects at this institution, with $151.3 million in listed awards. Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 9Clinical trials
- 335NIH research projects
- 1Country
Newest trials
All recruiting trials (9)
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Trying a deep-learning noise-reduction feature for hearing aids
This test tries a deep-learning noise-reduction feature in hearing aids to see if it helps people with mild-to-moderate cochlear hearing loss understand speech in noisy places.
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Dietary cysteine, gut microbes, and colorectal cancer risk
This trial will see if eating lower-cysteine versus higher-cysteine diets changes how the body and gut bacteria handle cysteine and reduces gut inflammation in Black and White adults aged 45–75 who previously had non-cancerous colon polyps.
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Effects of chicory inulin on gut microbiota in healthy adults
This study tests whether taking chicory inulin can change the gut bacteria in healthy adults and see how it affects their bowel habits, mood, and appetite.
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Effects of different grain foods on health in adults
This study is testing how different types of grain foods, like whole grains and refined grains, affect health in adults over 16 weeks.
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Effects of high-intensity interval training with mindfulness on children's brain function
This study is testing if a special workout that combines high-intensity exercises with mindfulness can help improve brain function in kids aged 10-12.
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Effects of mindfulness and exercise on children's cognitive function
This study is testing if a 12-week program that combines mindfulness and exercise can help improve thinking skills in kids aged 8-12 compared to other activities.
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Understanding the health impact of tetrachloroethylene exposure in Martinsville, IN
This study is trying to see how exposure to a chemical called tetrachloroethylene affects the health of people living in Martinsville, Indiana, and to help them understand the risks and make better health choices.
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Training to improve sentence production in people with aphasia
This study is testing a new way to help people with aphasia improve their ability to create and understand sentences using special training techniques.
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Improving nutrition education for children and parents facing food insecurity
This study is testing a new way to help children and their parents who use food assistance improve their eating habits and food security over time.
NIH-funded research (newest 40 of 335)
Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.
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Meltblown scaffolds to help irreparable rotator cuff tears
A new 3-D biomaterial scaffold made from meltblown technology aims to improve interposition grafts for people with irreparable rotator cuff tears.
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Targeting how RMS cells fail to mature to slow or stop pediatric muscle cancer spread
A project to understand why a pediatric muscle cancer called rhabdomyosarcoma spreads, and to test ideas that could slow or stop it by helping cancer cells mature properly.
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Risk stratification of malaria in school-age children using mobile eye-based spectroscopy
A low-cost, phone-based method uses pictures of the inner eyelid to identify which children in high-risk areas should get malaria tests.
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Dual-AAV gene replacement approach for SCN2A-related neurodevelopmental disorders
A gene therapy approach using two AAV vectors to restore SCN2A function in children with SCN2A-related neurodevelopmental disorders.
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Personalized use of newer diabetes medicines for Type 2 diabetes
Aiming to tailor use of newer glucose-lowering drugs for people with type 2 diabetes to improve health and access in real-world settings.
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Intelligent social risk management for people with Alzheimer's and related dementias
Aimed at people living with dementia, this project uses AI and real-world health data to identify and address social factors that affect their care and quality of life.
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How everyday cooking chemicals could affect dopamine nerve cells
This grant studies whether a common dietary chemical found in cooked foods can damage dopamine-producing brain cells linked to Parkinson’s disease, using laboratory models to understand the process.
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Upgrading veterinary diagnostic testing with a new HPLC/MS system
A Purdue-led project will acquire a high-performance HPLC/MS system to improve detection of toxic substances and nutrients in animals, animal foods, and related samples, helping protect pets, livestock, and public health.
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PFAS exposure and how it changes reward processing
This grant studies whether early life exposure to PFAS could affect brain reward systems and potentially contribute to conditions like anhedonia in humans and animals.
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Targeting NTMT1 to help people with muscular dystrophy
A researcher team at Purdue is testing a new druggable target called NTMT1 to help muscle repair in Duchenne muscular dystrophy.
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Hit-to-lead drug development for Acanthamoeba keratitis
A Purdue research team is developing new drug candidates to treat Acanthamoeba keratitis, a painful eye infection often linked to contact lens use and water exposure.
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Cross-species knowledgebase to boost precision auditory care
A cross-species knowledgebase will connect animal models to human hearing data to help personalize diagnosis and treatment for people with hearing loss.
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Retrieval-based Word Learning for Young Children with Developmental Language Disorder
A project helps 4- to 5-year-olds with language disorder learn new words more effectively using memory-based learning tricks.
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Music-based intervention to help people with aphasia recover language and thinking skills after stroke
A Purdue-led study tests whether listening to music can help adults with aphasia after a stroke improve language and thinking abilities.
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Reducing stuttering with smart feedback and brain-powered audio tweaks
A new device concept aims to help people who stutter by using a wearable earpiece that listens to speech, taps into brain activity, and delivers tailored altered feedback to improve fluency.
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Understanding how CAR T cells get activated and work
A proposed study at Purdue University looks at how CAR T cells activate at the cell surface and what makes them powerful or cause side effects, with the goal of making CAR T therapies safer and more effective for patients.
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Proteomics study on N-terminal acetylation in Alzheimer's disease vesicles
Researchers will use advanced mass spectrometry to study how a common protein modification in brain cells relates to Alzheimer’s disease and the spread of disease-related proteins via extracellular vesicles.
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Hyaluronan's role in how your tissues respond to physical forces
This grant studies how a tiny sugar called hyaluronan helps tissues like bone marrow and fat respond to physical stress, which matters for heart disease and aging.
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Covalent PI4K inhibitors to fight malaria
A new type of malaria drug candidate targets a parasite enzyme in a way that could overcome resistance and help people affected by malaria.
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Antibacterial materials inspired by tiny scorpion-like peptides
A Purdue-led project is creating new small, HDP-mimicking molecules to kill a wide range of bacteria and fight antibiotic resistance.
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ED-based Screening and Brief Intervention to Prevent Substance Use Disorder
A Purdue-led project will test if ED-based screening plus a brief in-person motivational talk and follow-up telehealth coaching can reduce risky substance use and prevent future disorder in diverse adults.
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Platinum-based countermeasures to treat cyanide poisoning and protect people
Aimed at developing safer, more effective platinum-based treatments and protective agents to rescue people from cyanide poisoning in emergencies.
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Cross-species study of immune responses to cancer immunotherapy in dogs and humans with invasive bladder cancer
A study using dogs with naturally occurring invasive bladder cancer to help improve immune checkpoint therapies for people with the same disease.
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Stromal targeting to help drugs reach pancreatic cancer tumors
Aims to improve drug delivery to pancreatic cancer by directly targeting the tumor’s surrounding tissue to help medicines reach cancer cells more effectively.
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Optimizing bacterial carbonic anhydrase inhibitors to treat vancomycin-resistant Enterococcus
A Purdue team is developing targeted bacterial drugs to fight vancomycin-resistant Enterococcus infections.
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Ligand-guided delivery of small RNAs to fight breast cancer
A new approach aims to safely deliver small RNA therapies directly to breast cancer tumors to slow or stop the disease.
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Posttranslational regulation of macropinocytosis in pancreatic cancer
This research looks at how pancreatic cancer cells use macropinocytosis and specific signaling to survive and grow, with the aim of finding new ways to slow down or stop the disease.
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AI-guided smart pacifier for real-time neonatal breathing monitoring
A new AI-powered, non-invasive sensor built into a smart pacifier could continuously monitor breathing in newborns to better understand and manage respiratory problems.
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SARS-CoV-2 protease inhibitors to treat COVID-19
Researchers at Purdue University are developing new drug compounds that block key SARS-CoV-2 proteases to help treat COVID-19.
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A math-based look at how plant stem cells shape fern growth
A project at Purdue uses math and computer models to understand how tiny fern cells move and divide to form stems and shapes.
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Nano-scale sensors to map single cells and mini-tumors metabolism and drug movement
A Purdue-led project will develop tiny electrochemical sensors to measure many cellular metabolites and how drugs move over time in individual cells and small cell clusters.
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How early childhood stress may change DNA marks linked to later depression
This work explores whether hard experiences in early childhood change DNA 'switches' and raise the chance of depression later on.
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Understanding how SARS-CoV-2 builds its outer shell and buds off
This project studies how the coronavirus SARS-CoV-2 assembles its protective envelope and leaves the cell, with the goal of identifying new ways to block the virus.
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Uncover how genes and lead exposure interact to drive Alzheimer's and related dementias as we age
This grant looks at how genetic factors and exposure to lead during development come together to influence aging brain changes that can lead to Alzheimer's and related dementias.
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Risk-based malaria screening in schoolchildren using phone-based eye images
A low-cost, phone-based tool helps identify which schoolchildren in malaria-endemic areas should get a confirmatory malaria test.
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Engineering the premetastatic niche in breast cancer
A Purdue University team is studying how breast cancer spreads to other parts of the body by modeling the distant tissue environment and finding key changes that help cancer cells take hold.
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Fluorination strategies to make new medicinal compounds
This grant supports developing new chemical methods to add fluorine to molecules, which can help create better medicines and biological tools.
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R-loops, aging, and Alzheimer’s disease: a new angle on how RNA modifications affect brain aging
A Purdue team will study how aging-related changes in RNA and DNA structures may drive Alzheimer’s disease, using a fruit-fly model to understand brain aging and immune responses.
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Smartphone eye-photo screening to find anemia and guide malaria testing in schoolchildren
This project uses smartphone photos of the inner eyelid to check for low blood counts and help decide which school-age children in malaria-prone areas should get a rapid malaria test.
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How early lead exposure may shape Alzheimer’s-related brain changes
This project looks at whether exposure to lead in early life can cause brain changes that resemble Alzheimer’s disease later on.
Quick answers
How many clinical trials run by Purdue University are recruiting right now?
9, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
All of them have sites in United States. Each study page lists its sites and which ones are recruiting.
What phases are they in?
Phase 1/2: 1. Trials with no phase listed are usually device, behavioural or observational studies.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.