NIH-funded research R01 grant

AI-guided smart pacifier for real-time neonatal breathing monitoring

Official title: SCH: AI-Guided Intraoral Multimodal Active Sound Sensing for Advanced Pulmonary Function Characterization

Funded at Purdue University · NIH-11397767 · Data updated 2026-11-12

A new AI-powered, non-invasive sensor built into a smart pacifier could continuously monitor breathing in newborns to better understand and manage respiratory problems.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionPurdue University
NIH-funded
Lab location1 site (West Lafayette, United States)
Project startSeptember 1, 2025
Project endJuly 31, 2029
Funding year2026
Award (this year)$299,690
NIH project number5R01HL184140-02
Project IDNIH-11397767 on NIH RePORTER

Who could benefit from this research

Could help

Newborns with respiratory concerns or at high risk of respiratory distress in neonatal care settings.

Less likely to help

Healthy term newborns without respiratory issues may experience limited direct benefit from this device.

What this research studies

This project develops a compact smart pacifier that uses active sound sensing and AI analysis to monitor neonates’ breathing in real time. It creates a multimodal approach, emitting gentle sound stimuli and interpreting reflections to assess lung function with a specialized neural network (MASS-RespNet). The research includes designing low-power hardware, integrating sensors into a neonatal device, and building an AI pipeline that can deliver actionable respiratory insights at the bedside. The goal is to improve early detection of respiratory distress and guide care for vulnerable infants while minimizing discomfort and risk.

Why it matters

Potential benefit: If successful, it could enable continuous, non-invasive respiratory monitoring in newborns, potentially reducing complications and hospital stays.

How similar studies have gone: Previous work in neonatal monitoring with non-invasive sensors shows promise, but integration with AI-driven active sound sensing in a pacifier is novel.

Where this research is happening

  • Purdue University
    West Lafayette, United States
    Active

Researchers

  • Principal investigator: Faezipour, Miad — Purdue University
  • Study coordinator: Faezipour, Miad

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
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Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.