Clinical trial Recruiting at 1 site Interventional Ages 18 to 99

Understanding the health impact of tetrachloroethylene exposure in Martinsville, IN

Official title: Addressing Tetrachloroethylene Exposure in an Impacted Community: Residents' Concerns, Neurotoxic Effects, and Exposure Reduction

Run by Purdue University · NCT05819996 · Data updated 2026-11-12

This study is trying to see how exposure to a chemical called tetrachloroethylene affects the health of people living in Martinsville, Indiana, and to help them understand the risks and make better health choices.

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Quick facts

Study typeInterventional
Ages18 Years to 99 Years
SexAll
Enrollment510 (estimated)
SponsorPurdue University
Academic / other
Locations1 site (West Lafayette, Indiana)
StatusRecruiting
StartedFebruary 17, 2023
Main results expectedMay 31, 2028
Study endsMay 31, 2028
Registry record updatedMarch 18, 2025
Trial IDNCT05819996 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are residents of Martinsville, Indiana, who are 18 years or older.

Probably not a fit

Patients who do not reside in Martinsville or are under 18 years old may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study focuses on the community of Martinsville, Indiana, which is affected by groundwater contamination from volatile organic compounds, specifically tetrachloroethylene (PCE) and trichloroethylene (TCE). Researchers will measure exposure levels in residents' homes and assess community perceptions regarding health risks associated with these contaminants. An environmental educational campaign will be implemented to empower residents in making informed decisions about their health and environment. The ultimate goal is to understand the health impacts of low-level PCE exposure and guide community actions.

Why it matters

Potential benefit: If successful, this study could lead to improved health outcomes for residents by informing them about the risks of exposure and guiding effective community interventions.

How similar studies have gone: Other studies have shown success in addressing community health impacts from environmental contamination, making this approach both relevant and potentially effective.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Residents of Martinsville, Indiana
* 18 years or older

Where it's running

  • Purdue University
    West Lafayette, Indiana, United States
    Recruiting

Study contacts

  • Principal investigator: Sa Liu, MPH, PhD — Purdue University
  • Study coordinator: Sa Liu, MPH, PhD
  • Email: saliu@purdue.edu
  • Phone: 765-496-6240

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.