NIH-funded research R01 grant

Personalized use of newer diabetes medicines for Type 2 diabetes

Official title: Building Personalized Therapeutic Strategies for Newer Glucose-Lowering Drugs in People with Type 2 Diabetes

Funded at Purdue University · NIH-11571362 · Data updated 2026-11-12

Aiming to tailor use of newer glucose-lowering drugs for people with type 2 diabetes to improve health and access in real-world settings.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionPurdue University
NIH-funded
Lab location1 site (West Lafayette, United States)
Project startJuly 20, 2022
Project endJune 30, 2027
Funding year2025
Award (this year)$231,610
NIH project number7R01DK133465-05
Project IDNIH-11571362 on NIH RePORTER

Who could benefit from this research

Could help

Adults with type 2 diabetes who are candidates for newer glucose-lowering drugs and who have varying levels of access and resources.

Less likely to help

Patients who do not require newer GLDs or for whom these drugs are not appropriate due to medical reasons.

What this research studies

This project looks at how to customize when and how to use newer, higher-cost diabetes medicines so that people with type 2 diabetes can get the best outcomes without financial hardship. It will examine data from real-world patient experiences to understand which patients benefit most from these drugs and how to optimize treatment over time. The goal is to generate practical guidance that clinicians can use to choose therapies that improve heart and kidney health while considering costs. The study builds on prior work showing benefits of newer GLDs and seeks to fill gaps about who benefits most in diverse, real-life populations.

Why it matters

Potential benefit: If successful, it could help clinicians choose better, more affordable treatment plans for people with type 2 diabetes.

How similar studies have gone: Prior CER work suggests some personalized strategies work, but knowledge gaps remain about who benefits most from newer GLDs in real practice.

Where this research is happening

  • Purdue University
    West Lafayette, United States
    Active

Researchers

  • Principal investigator: Guo, Jingchuan — Purdue University
  • Study coordinator: Guo, Jingchuan

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.