Smartphone eye-photo screening to find anemia and guide malaria testing in schoolchildren

Risk stratification of malaria among school-age children with mHealth spectroscopy of blood analysis

['FUNDING_OTHER'] · PURDUE UNIVERSITY · NIH-11381358

This project uses smartphone photos of the inner eyelid to check for low blood counts and help decide which school-age children in malaria-prone areas should get a rapid malaria test.

Quick facts

Phase['FUNDING_OTHER']
Study typeNih_funding
SexAll
SponsorPURDUE UNIVERSITY (nih funded)
Locations1 site (WEST LAFAYETTE, UNITED STATES)
Trial IDNIH-11381358 on ClinicalTrials.gov

What this research studies

From a parent or student's view, a low-cost smartphone app will take a photo of the inside of the lower eyelid to estimate blood hemoglobin without a finger prick. Those hemoglobin readings will be combined with questions about recent fever or illness to identify children more likely to have malaria. Children flagged by the app would then receive a standard malaria rapid diagnostic test (RDT), while others could avoid unnecessary testing. The work focuses on school-age children in malaria-endemic parts of sub-Saharan Africa and builds on earlier mobile-phone hemoglobin methods.

Who could benefit from this research

Good fit: Ideal candidates are school-age children (roughly 6–15 years old) in malaria-endemic regions where the smartphone screening is offered.

Not a fit: Young children under age five, people with severe or urgent illness, or anyone outside the participating schools or regions are unlikely to benefit from this screening approach.

Why it matters

Potential benefit: If successful, this approach could find hidden malaria infections in schoolchildren while reducing unnecessary rapid tests and saving resources.

How similar studies have performed: Prior pilot work has shown smartphone photos can predict hemoglobin reasonably well, but using that signal to prescreen schoolchildren for malaria RDTs is a newer application.

Where this research is happening

WEST LAFAYETTE, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.