Training to improve sentence production in people with aphasia
Structural Priming as a Treatment Component in Aphasia
This study is testing a new way to help people with aphasia improve their ability to create and understand sentences using special training techniques.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 104 (estimated) |
| Ages | 21 Years to 85 Years |
| Sex | All |
| Sponsor | Purdue University Academic / other |
| Locations | 1 site (West Lafayette, Indiana) |
| Trial ID | NCT05415501 on ClinicalTrials.gov |
What this trial studies
This project aims to develop a new treatment for enhancing sentence production and comprehension in individuals with aphasia through implicit priming techniques. The study will be conducted over five years and will include a series of experiments to identify the most effective learning conditions for maximizing training gains. The researchers will investigate how implicit learning can facilitate language recovery and will assess the generalization of improvements across different language tasks. Ultimately, the goal is to establish an effective intervention strategy based on the findings from these studies.
Who should consider this trial
Good fit: Ideal candidates include individuals who are at least six months post-stroke with aphasia and have some ability to use words independently.
Not a fit: Patients with severe apraxia of speech or other neurological conditions affecting communication may not benefit from this study.
Why it matters
Potential benefit: If successful, this treatment could significantly improve communication abilities for patients with aphasia.
How similar studies have performed: Other studies have shown promise in using implicit learning techniques for language recovery, suggesting potential success for this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Individuals with post-stroke aphasia * At least 6 months post-onset of eft hemisphere stroke * Native speaker of English * Normal or corrected to normal hearing and vision * High-school educated * Difficulty communicating in sentences, with some ability to use words independently Exclusion Criteria: * Severe apraxia of speech * Other neurological conditions affecting communication (e.g., dementia) * Uncontrolled psychiatric/psychological conditions affecting thinking and communication * Active alcohol/substance abuse
Where this trial is running
West Lafayette, Indiana
- Purdue University — West Lafayette, Indiana, United States (Recruiting)
Study contacts
- Principal investigator: Jiyeon Lee, PhD — Purdue University
- Study coordinator: Jiyeon Lee, PhD
- Email: lee1704@purdue.edu
- Phone: 7654943810
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.