Training to improve sentence production in people with aphasia

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This project aims to develop a new treatment for enhancing sentence production and comprehension in individuals with aphasia through implicit priming techniques. The study will be conducted over five years and will include a series of experiments to identify the most effective learning conditions for maximizing training gains. The researchers will investigate how implicit learning can facilitate language recovery and will assess the generalization of improvements across different language tasks. Ultimately, the goal is to establish an effective intervention strategy based on the findings from these studies.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Individuals with post-stroke aphasia
* At least 6 months post-onset of eft hemisphere stroke
* Native speaker of English
* Normal or corrected to normal hearing and vision
* High-school educated
* Difficulty communicating in sentences, with some ability to use words independently

Exclusion Criteria:

* Severe apraxia of speech
* Other neurological conditions affecting communication (e.g., dementia)
* Uncontrolled psychiatric/psychological conditions affecting thinking and communication
* Active alcohol/substance abuse

Where it's running

• Purdue University
  West Lafayette, Indiana, United States Recruiting

Study contacts

• Principal investigator: Jiyeon Lee, PhD — Purdue University
• Study coordinator: Jiyeon Lee, PhD
• Email: lee1704@purdue.edu
• Phone: 7654943810

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• See how language and general thinking networks help aphasia recovery

  This study tests whether language and general cognitive networks contribute to language recovery after stroke in people with aphasia.

  Recruiting Boston University Charles River Campus · Boston, Massachusetts · NCT07926347

• Aphasia rehabilitation with tDCS as added to speech therapy

  We are testing whether adding non-invasive brain stimulation (tDCS) to speech therapy helps people with Broca's aphasia after stroke more than speech therapy alone.

  Recruiting at 3 sites Phase 2/3 University of South Carolina · Charleston, South Carolina and 2 other locations · NCT07688551

• Tailoring rTMS for Post-Stroke Aphasia Based on Language Profile

  A non-drug brain stimulation approach is tested to see if customizing rTMS targets improves language recovery in people with aphasia after a left-brain stroke.

  Recruiting University of South Carolina · Columbia, South Carolina · NCT07608588

• LEXURE digital language therapy for post-stroke aphasia

  This trial will test whether using the LEXURE app helps adults with post-stroke aphasia improve language more than workbook-based practice.

  Recruiting at 8 sites Nunaps Inc · Ansan, Gyeonggi-do and 11 other locations · NCT07570264

• tDCS in Rehab for Stroke-Related Aphasia: A Practical Implementation

  This study tests whether a 20-minute anodal tDCS session paired with speech therapy can be integrated into routine inpatient and outpatient rehab for people who recently had a stroke and now have aphasia.

  Recruiting Casa Colina Hospital and Centers for Healthcare · Pomona, California · NCT07535788

• New tools to measure language, gestures, and everyday communication in people with aphasia

  This project will test new ways to measure language, gestures, and everyday communication skills in adults with aphasia after stroke.

  Recruiting IRCCS San Camillo, Venezia, Italy · Venice, VE · NCT07518576

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.