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Clinical trials and research at Northwell Health

• 80Clinical trials
• 2New in 30 days
• 2Countries

Newest trials

All recruiting trials (80)

• Brain connectome project in adults with brain glioma undergoing surgery

  This registry collects MRI data and clinical information from adults with glioma to see how brain networks relate to surgery and recovery.

  Recruiting Northwell Health · New York, New York · NCT07927595

• Pain relief during urethral bulking: comparing lidocaine versus saline injections

  We’re testing whether injecting lidocaine around the urethra reduces pain more than a saline placebo during urethral bulking for stress urinary incontinence.

  Recruiting at 3 sites Phase 4 Northwell Health · Bay Shore, New York and 2 other locations · NCT07889687

• Increased fruit juice for better exercise ability and lower inflammation

  This study will test whether drinking two fruit juice beverages daily for two weeks can influence inflammatory markers and how far people can walk in six minutes.

  Recruiting Northwell Health · New York, New York · NCT07862049

• Breast Artery Calcification and Heart Health in Women

  This study tests whether a breast artery calcification finding on a mammogram is linked to different cardiovascular markers in women 55–65 who do or do not have BAC.

  Recruiting Northwell Health · Manhasset, New York · NCT07809932

• Vagustim taVNS: Testing a sham in adults for immune-related conditions

  This small, double-blind study tests whether Vagustim taVNS’s sham method works as a believable placebo in healthy adults.

  Recruiting Northwell Health · New Hyde Park, New York · NCT07791290

• Brain-derived miRNA biomarkers in first-episode psychosis

  Researchers will test whether specific brain-derived microRNAs in blood can help identify schizophrenia early and track treatment in people with first-episode psychosis on aripiprazole or risperidone.

  Recruiting Northwell Health · Glen Oaks, New York · NCT07703670

• Post transplant cyclophosphamide, bortezomib, and sitagliptin to prevent graft-versus-host disease after allogeneic transplantation

  This study tests whether a combination of post-transplant cyclophosphamide, bortezomib, and sitagliptin can prevent GvHD in adults undergoing reduced-intensity allogeneic stem cell transplantation from matched related or unrelated donors.

  Recruiting Phase 1/2 Northwell Health · New Hyde Park, New York · NCT07675174

• One-chamber leadless atrial pacing and loop recorder follow-up in sinus node dysfunction

  This study tests whether an atrial leadless pacemaker with a loop recorder can help manage symptomatic sinus bradycardia and see if new atrial fibrillation occurs.

  Recruiting at 6 sites Northwell Health · Bay Shore, New York and 5 other locations · NCT07638995

• Coordinated Communication, Education, and Care Transitions After Acute Kidney Injury (CONNECT-AKI)

  This study tests whether a discharge summary template and a chat-based education program help adults with AKI understand their condition and follow up after leaving the hospital.

  Recruiting at 2 sites Northwell Health · Glen Oaks, New York and 1 other locations · NCT07626268

• See if repetitive transcranial magnetic stimulation helps with dystonia symptoms

  This study tests whether applying rTMS can alter brain activity to help people with dystonia.

  Recruiting Northwell Health · Manhasset, New York · NCT07626216

• Galantamine treatment for metabolic syndrome in people with spinal cord injury

  This study tests whether galantamine can help reduce metabolic syndrome and inflammation in adults with chronic spinal cord injury.

  Recruiting at 2 sites Phase 2/3 Northwell Health · West Orange, New Jersey and 2 other locations · NCT07625332

• Remapping Before/During LAAO: Testing Durable Pulsed Field Ablation for Atrial Fibrillation

  We’re testing whether a pulsed field ablation done during a planned left atrial appendage occlusion procedure stays effective over time in adults with atrial fibrillation.

  Recruiting Northwell Health · Bay Shore, New York · NCT07620262

• Connectomic changes after stroke in the middle cerebral artery area

  This study tests how brain networks change after an MCA stroke using MRI and machine learning to help predict recovery and guide rehabilitation.

  Recruiting Northwell Health · New York, New York · NCT07584681

• Comparing the Optrell mapping catheter for papillary muscle ventricular arrhythmias

  This test sees if the Optrell mapping catheter helps doctors map and treat papillary muscle ventricular arrhythmias faster and more accurately in adults having ablation.

  Recruiting Northwell Health · New Hyde Park, New York · NCT07541092

• Cerebellar imaging markers to predict antipsychotic response in first-episode psychosis

  This will test whether cerebellar brain scans can predict how people with first-episode psychosis respond to 12 weeks of treatment with risperidone or aripiprazole.

  Recruiting Phase 4 Northwell Health · Glen Oaks, New York · NCT07483294

• Using BaroStim and CardioMems to improve care for NYHA Class III heart failure

  This study will see if adding BaroStim after three months of CardioMems-guided medication optimization helps people with NYHA Class III heart failure and LVEF under 35%.

  Recruiting Phase 2/3 Northwell Health · Riverhead, New York · NCT07399587

• Immune response to histotripsy in colorectal cancer liver metastases

  This pilot will test whether histotripsy, a noninvasive liver tumor treatment, changes blood T‑cell responses in people with colorectal cancer that has spread to the liver.

  Recruiting Phase 1 Northwell Health · New Hyde Park, New York · NCT07361107

• Factors that affect atrial tracking and atrial fibrillation in people receiving the Micra AV2 pacemaker

  This will see how well the Micra AV2 device tracks atrial activity and how often short episodes of paroxysmal atrial fibrillation occur in adults who receive the device.

  Recruiting Northwell Health · New Hyde Park, New York · NCT07344961

• Implantable microdevice placed during pancreatic cancer surgery to test tumor drug response

  This will test whether a tiny implantable device placed during pancreatic cancer surgery can show how an individual's tumor responds to chemotherapy.

  Recruiting Early Phase 1 Northwell Health · New Hyde Park, New York · NCT07254091

• Starting Early to Prevent Obesity Using Telehealth (StEP OUT) for pregnant Latino families

  This trial will test whether an online program (StEP OUT) can teach healthy pregnancy and infant feeding habits to pregnant Hispanic/Latinx people to help prevent early childhood obesity.

  Recruiting Northwell Health · New Hyde Park, New York · NCT07254065

• Pressurized aerosol chemotherapy (PIPAC) for pancreatic cancer that has spread to the peritoneum

  This will try PIPAC (pressurized intraperitoneal aerosolized chemotherapy) with nab-paclitaxel in adults whose pancreatic adenocarcinoma has spread to the lining of the abdomen to see if it improves drug delivery and clinical outcomes.

  Recruiting Phase 1 Northwell Health · New Hyde Park, New York · NCT07253662

• Implantable microdevice to test drug effects inside colorectal liver tumors

  This will try placing a tiny implant into liver metastases to see if different cancer drugs diffuse into and affect the tumor tissue in adults scheduled for surgery for colorectal cancer spread to the liver.

  Recruiting at 2 sites Early Phase 1 Northwell Health · Lake Success, New York and 1 other locations · NCT07193862

• Mobilizing CD34+ stem cells in Diamond Blackfan anemia

  This will see if people with Diamond Blackfan anemia can mobilize enough CD34+ stem cells into the blood so they can be collected for possible future gene therapy.

  Recruiting Northwell Health · New Hyde Park, New York · NCT07186179

• Nelitolimod immunotherapy given to the liver before planned removal of colorectal cancer metastases

  This will test whether giving nelitolimod directly into the liver before surgery can boost the immune response against colorectal cancer that has spread to the liver.

  Recruiting Early Phase 1 Northwell Health · Lake Success, New York · NCT07172282

• Monthly alternating NALIRIFOX and gemcitabine plus nab‑paclitaxel for metastatic pancreatic cancer

  This trial will test whether giving NALIRIFOX and gemcitabine plus nab‑paclitaxel in monthly alternating cycles helps adults with metastatic pancreatic ductal adenocarcinoma control their cancer and live longer.

  Recruiting at 7 sites Phase 2 Northwell Health · Bay Shore, New York and 6 other locations · NCT07163273

• 10-day versus 6-week low-residue diet after colon resection with an anastomosis

  This study will test whether returning to a regular diet after 10 days instead of staying on a low-residue diet for 6 weeks helps people recover bowel function faster after elective colon resection with an anastomosis.

  Recruiting at 2 sites Northwell Health · Manhasset, New York and 1 other locations · NCT07083076

• Bilateral middle meningeal artery lidocaine infusion to treat chronic, debilitating migraines

  This Phase 2 procedure will test whether injecting lidocaine into the middle meningeal arteries can reduce the frequency, intensity, and duration of chronic, treatment‑resistant migraines in adults.

  Recruiting Phase 2 Northwell Health · Great Neck, New York · NCT07061847

• FEIBA versus fresh frozen plasma as first-line treatment for bleeding after cardiac surgery

  This Phase 2 trial will test whether FEIBA works better than fresh frozen plasma (FFP) as the first treatment for adults who develop coagulopathic microvascular bleeding after non-emergency cardiac surgery with cardiopulmonary bypass.

  Recruiting Phase 2 Northwell Health · Manhasset, New York · NCT07032792

• Transcutaneous vagus nerve stimulation for muscular pain and fatigue in SLE

  This trial tests whether applying gentle skin stimulation over the neck or ear to activate the vagus nerve can reduce musculoskeletal pain and fatigue in people with systemic lupus erythematosus.

  Recruiting Phase 2 Northwell Health · Manhasset, New York · NCT06987565

• Digital snapshot to reduce restraints and improve emergency care for adults with intellectual and developmental disabilities

  We will test whether the Always Uniquely Me mobile app can reduce use of physical restraints and improve emergency department experiences for adults with intellectual and developmental disabilities.

  Recruiting Northwell Health · New Hyde Park, New York · NCT06986863

• Biomarker-guided early treatment for schizophrenia

  This trial tests whether starting clozapine early, based on three biomarkers, helps people aged 18–35 who are having a first episode of psychosis and are likely to not respond to standard antipsychotics but are at low genetic risk for serious side effects.

  Recruiting at 5 sites Phase 4 Northwell Health · Birmingham, Alabama and 4 other locations · NCT06969755

• Trans-arterial embolization to treat lumbar facet joint pain

  This single-site effort will try trans-arterial embolization with Embozene microparticles to see if it reduces lumbar facet (facetogenic) pain in adults with osteoarthritis who have not improved with standard treatments.

  Recruiting Northwell Health · Manhasset, New York · NCT06965452

• Ultrasound of the Spleen at Diagnostic Levels to See if Platelet Activity Changes

  This study tests whether low-energy ultrasound focused on the spleen can alter blood clotting markers in healthy adults aged 18–50.

  Recruiting Northwell Health · Manhasset, New York · NCT06934096

• Patient-centered decision-making for mitral valve prolapse treatment

  This study is trying to understand what patients with mitral valve prolapse and their doctors think about choosing between two treatment options, surgery or a less invasive procedure, to help improve how they make decisions together.

  Recruiting at 5 sites Northwell Health · Los Angeles, California and 4 other locations · NCT06738537

• Evaluating opioid-free pain management before urogynecologic surgeries

  This study is testing if a combination of pain relievers without opioids can help women recover faster after certain bladder surgeries.

  Recruiting Phase 4 Northwell Health · Bay Shore, New York · NCT06379425

• Recording brain activity in patients with lupus

  This study tests how brain activity in lupus patients relates to thinking problems by using a special cap to record their brain waves while they do simple tasks.

  Recruiting Northwell Health · Manhasset, New York · NCT06378736

• Investigating tau biomarkers in older adults with late-onset psychosis

  This study is trying to see if older adults with late-onset psychosis are at a higher risk for developing Alzheimer's disease by looking at new blood tests and brain scans.

  Recruiting Northwell Health · Manhasset, New York · NCT06336382

• Integrated care model for high-risk Black and Hispanic/Latina birthing people

  This study tests if a new care approach with more support can help high-risk Black and Hispanic/Latina birthing people have safer pregnancies and reduce serious health problems.

  Recruiting Northwell Health · Manhasset, New York · NCT06335381

• Comparing two suturing techniques for skin grafts

  This study is testing whether a new way of stitching skin grafts looks just as good as the traditional method by comparing the results on the same person's scars.

  Recruiting Northwell Health · North New Hyde Park, New York · NCT06233812

• Using iTBS to Improve Social Cognition in People with Psychosis

  This study is testing whether a new brain stimulation treatment can help people with schizophrenia improve their social skills and thinking.

  Recruiting Northwell Health · Glen Oaks, New York · NCT06118268

• Comparing two doses of growth hormone in children with growth deficiency

  This study is testing whether a higher or lower dose of growth hormone helps children with growth deficiency grow taller and stay safe during treatment.

  Recruiting Phase 3 Northwell Health · New York, New York · NCT06103513

• Using ultrasound through transparent skull implants for brain imaging

  This study is testing if using ultrasound through clear skull implants can provide a safer and easier way to take brain images for patients who have had cranial surgery.

  Recruiting Northwell Health · New York, New York · NCT06097845

• Deep brain stimulation for treatment resistant depression

  This study is testing if deep brain stimulation can help people with treatment-resistant depression feel better by comparing their symptoms when the device is on and off.

  Recruiting Phase 1 Northwell Health · Queens, New York · NCT06096207

• Real-time imaging during brain tumor surgery

  This study tests a new handheld imaging tool during brain tumor surgery to see if it helps doctors better tell the difference between healthy and tumor tissue in patients.

  Recruiting Northwell Health · Manhasset, New York · NCT06087393

• SMART goals program for youth with prediabetes

  This study is testing if a special goal-setting program can help overweight kids with prediabetes lose weight and improve their health compared to regular care.

  Recruiting at 2 sites Northwell Health · New York, New York and 1 other locations · NCT06067451

• Comparing a new bioactive sleeve to a placebo for pain relief after meniscus surgery

  This study is testing a new pain-relief sleeve after meniscus surgery to see if it helps patients recover better than a fake sleeve.

  Recruiting Northwell Health · Woodbury, New York · NCT06041321

• Using omental tissue to treat recurrent glioblastoma

  This study is testing whether using a piece of fat from the abdomen can help improve treatment for patients with recurrent glioblastoma by delivering medication and immune cells more effectively to the tumor site.

  Recruiting Northwell Health · New York, New York · NCT05979064

• Surgical technique to improve outcomes in glioblastoma patients

  This study is testing a new surgical method using special tissue flaps to see if it can help people with newly diagnosed glioblastoma live longer and have fewer problems after surgery.

  Recruiting Northwell Health · New York, New York · NCT05954858

• Radiofrequency ablation for benign thyroid nodules in LatinX patients

  This study is testing if a new, less invasive treatment called radiofrequency ablation can safely help LatinX patients with bothersome benign thyroid nodules feel better.

  Recruiting Northwell Health · New York, New York · NCT05903196

• Understanding brain mechanisms of psychosis in Alzheimer's disease

  This study is trying to understand how changes in the brain related to tau protein might cause psychotic symptoms in people with Alzheimer's disease.

  Recruiting Northwell Health · Manhasset, New York · NCT05847192

• Monitoring heart rhythms in patients starting BTK inhibitors

  This study is testing how well a heart monitor can detect new heart rhythm problems in patients starting treatment with BTK inhibitors.

  Recruiting Northwell Health · New Hyde Park, New York · NCT05643235

• Blood test for detecting HPV-related gynecologic cancers

  This study is testing a blood test that looks for HPV-related cancer DNA in women with serious cervical issues to see if it can help detect and monitor these cancers without needing invasive procedures.

  Recruiting Northwell Health · New York, New York · NCT05606133

• Vagus nerve stimulation for treating nephrotic syndrome in children

  This study is testing whether a new treatment using vagus nerve stimulation can help children aged 3 to 17 with nephrotic syndrome feel better and reduce their symptoms.

  Recruiting at 2 sites Northwell Health · New Hyde Park, New York and 1 other locations · NCT05588063

• Using vagus nerve stimulation to treat nephrotic syndrome in children

  This study is testing if a new type of nerve stimulation can help children with steroid-resistant nephrotic syndrome feel better over 26 weeks.

  Recruiting at 2 sites Northwell Health · New Hyde Park, New York and 1 other locations · NCT05583942

• Comparing endoscopic and surgical methods for treating gastric outlet obstruction

  This study is testing whether a less invasive endoscopic procedure or a traditional surgery works better for treating gastric outlet obstruction caused by cancer.

  Recruiting Northwell Health · New Brunswick, New Jersey and 3 other locations · NCT05561907

• Comparing Doppler Ultrasound and Manual Pulse Checks in Cardiac Arrest

  This study is testing a new device that uses ultrasound to check blood flow in the neck of cardiac arrest patients to see if it can accurately tell when their heart starts beating again.

  Recruiting Northwell Health · Manhasset, New York · NCT05558228

• Comparing infection rates after hip replacement using a special solution versus saline

  This study is testing if a special solution can lower the risk of joint infections after hip replacement surgery compared to regular saline.

  Recruiting at 3 sites Northwell Health · Manhasset, New York and 2 other locations · NCT05519007

• Effects of cerebellar TMS on cognitive functions in schizophrenia

  This study is testing if a new brain treatment called rTMS can improve thinking skills in young adults with schizophrenia.

  Recruiting Northwell Health · New York, New York · NCT05389787

• Using Biparametric MRI to Screen for Prostate Cancer in High-Risk Individuals

  This study is testing if using a special type of MRI along with blood tests can help find prostate cancer earlier in men aged 40-55 who are at high risk.

  Recruiting Northwell Health · Lake Success, New York · NCT05384535

• Post-Transplant GvHD Prophylaxis with PTCy, Bortezomib, and Abatacept

  This study tests whether adding abatacept to a standard post-transplant prophylaxis (PTCy and bortezomib) can reduce graft-versus-host disease in adults after allogeneic HSCT from matched related or matched/unrelated donors.

  Recruiting Phase 1/2 Northwell Health · New Hyde Park, New York · NCT05289167

• Treatment of low-risk submassive pulmonary embolism using FlowTriever

  This study is testing if the FlowTriever device can safely treat people with low-risk submassive pulmonary embolism who are stable and have certain health markers.

  Recruiting Northwell Health · Mount Kisco, New York and 1 other locations · NCT05273762

• Infusion of Bevacizumab with Chemotherapy and Radiation for Newly Diagnosed Glioblastoma

  This study is testing if adding a special infusion of Bevacizumab to standard chemotherapy and radiation can help people with newly diagnosed glioblastoma live longer and feel better.

  Recruiting Phase 3 Northwell Health · New York, New York · NCT05271240

• Urolift Before SBRT to Try to Lower Urinary Side Effects in Men with BPH and Prostate Cancer

  This study tests whether doing Urolift before SBRT can lessen urinary side effects for men with BPH and prostate cancer needing radiation therapy.

  Recruiting Northwell Health · Syosset, New York · NCT05148156

• Using 3D ultrasound to map vascular problems in people with PAD and related wounds

  This study tests a 3D freehand ultrasound tool to help explain vascular disease to patients and support care at the wound center.

  Recruiting Northwell Health · Lake Success, New York · NCT05134311

• Improving social functioning and reducing psychosis risk through cognitive training

  This study is testing a 10-week program to see if cognitive training can help teenagers at risk for psychosis improve their thinking skills and social interactions.

  Recruiting Northwell Health · Glen Oaks, New York · NCT05131035

• Trying PureWick to help with nighttime urination in older adults

  This pilot study tests whether using PureWick at night can reduce nighttime bathroom trips and related falls for adults 50 and older who wake up to urinate at least twice per night.

  Recruiting Northwell Health · New York, New York and 1 other locations · NCT05090722

• Understanding brain changes in essential tremor after deep brain stimulation

  This study is testing how deep brain stimulation affects brain connections in people with essential tremor who haven't found relief from medication.

  Recruiting Northwell Health · Manhasset, New York · NCT04758624

• Using electrical stimulation to improve movement in people with paralysis or weakness

  This study is testing if using electrical stimulation can help people with paralysis or weakness from spinal cord injuries or strokes improve their movement.

  Recruiting Early Phase 1 Northwell Health · Manhasset, New York · NCT04755699

• Evaluating Medrol Dose Pack for treating headaches after concussions

  This study is testing if a medication called Medrol can help people with headaches after a concussion feel better and get back to their normal activities faster.

  Recruiting Northwell Health · Manhasset, New York · NCT04685772

• Restoring hand and wrist function in people with tetraplegia using a neural device

  This study is testing a new device to see if it can help people with tetraplegia regain movement and feeling in their hands and wrists.

  Recruiting Northwell Health · Manhasset, New York · NCT03680872

• Using Anakinra to treat Meniere's Disease and Autoimmune Inner Ear Disease

  This study is testing if the drug anakinra can help people with Meniere's disease and autoimmune inner ear disease who don't respond to steroids, by seeing if it improves their hearing over 42 days compared to a placebo.

  Recruiting Phase 2 Northwell Health · New Hyde Park, New York · NCT03587701

• Evaluating belimumab for early lupus treatment

  This study is testing if the drug belimumab can help people who have been diagnosed with lupus in the last two years feel better and possibly stay in remission.

  Recruiting Phase 4 Northwell Health · Manhasset, New York · NCT03543839

• Combining capecitabine and temozolomide for newly diagnosed glioblastoma

  This study is testing if combining two cancer drugs, capecitabine and temozolomide, can help people with newly diagnosed glioblastoma live longer and feel better compared to using temozolomide alone.

  Recruiting Phase 1/2 Northwell Health · New York, New York · NCT03213002

• Comparing electrical stimulation and physical therapy for knee pain

  This study is testing if using an electrical stimulation device along with physical therapy can help people with knee pain recover faster and feel better compared to just physical therapy alone.

  Recruiting Phase 3 Northwell Health · New York, New York · NCT03184545

• Treatment of newly diagnosed glioblastoma using targeted drug infusion

  This study is testing a new way to deliver a targeted drug directly to the brain tumor in people with newly diagnosed glioblastoma to see if it can improve their treatment outcomes.

  Recruiting Phase 1/2 Northwell Health · New York, New York · NCT02861898

• Targeting brain tumors with a specific drug infusion and re-irradiation

  This study is testing a new way to deliver a drug directly to brain tumors in patients with certain aggressive types of glioblastoma to see if it can improve treatment results.

  Recruiting Phase 2 Northwell Health · New York, New York · NCT02800486

• Deep brain stimulation for severe obsessive-compulsive disorder

  This study is testing if deep brain stimulation can help people with severe obsessive-compulsive disorder who haven't found relief from other treatments.

  Recruiting Northwell Health · Queens, New York · NCT02773082

• Using targeted delivery of Bevacizumab for treating recurrent brain tumors

  This study is testing a new way to deliver the cancer drug Bevacizumab directly to the brain to see if it helps people with recurrent brain tumors live longer and feel better compared to the usual method of giving it through an IV.

  Recruiting Phase 1/2 Northwell Health · New York, New York · NCT01269853

• Tissue bank for human blood cell disorders

  This study is creating a tissue bank of blood samples from patients with blood cell disorders so researchers can learn more about these conditions and how they compare to healthy blood cells.

  Recruiting Northwell Health · Manhasset, New York · NCT00902447

• Registry for patients with Diamond Blackfan anemia

  This study is creating a registry to collect information from people with Diamond Blackfan anemia to better understand the condition and its complications.

  Recruiting Northwell Health · New Hyde Park, New York · NCT00106015

Quick answers

How many clinical trials run by Northwell Health are recruiting right now?

80, as of November 12, 2026. 2 of them were first registered in the last 30 days. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 2 countries. The most sites are in United States (80 trials), Canada (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 6, Phase 4: 5, Phase 1/2: 5, Early Phase 1: 4. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

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