Comparing a new bioactive sleeve to a placebo for pain relief after meniscus surgery

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial evaluates the effectiveness of a novel bioactive sleeve designed to reduce pain and improve recovery outcomes after meniscus surgery. It is a blinded randomized prospective study involving approximately 100 patients who will be assigned to receive either the bioactive sleeve or a placebo sleeve that looks and feels similar. The study will assess various patient-reported outcomes and physical therapy metrics at multiple time points post-surgery to determine the sleeve's impact on healing and pain management.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Provision of signed and dated informed consent form
* Stated willingness to comply with all study procedures and availability for the duration of the study
* Male or female, over the age of 18, undergoing a meniscectomy or meniscus repair
* In good general health as evidenced by medical history
* Under 45th percentile BMI
* Willing to adhere to the study intervention regimenregimen.
* Kellgren-Lawrence grade 2 or less

Exclusion Criteria:

* Febrile illness within 3 months
* BMI over 40
* Treatment with another investigational drug or other intervention within 6 months
* Kellgren-Lawrence grade 3 or more or 4
* History of autoimmune disease, circulatory disease, or vascular disorder

Where it's running

• Orlin and Cohen Orthopedics
  Woodbury, New York, United States Recruiting

Study contacts

• Study coordinator: Puja Mishra, MS
• Email: pmishra2@orlincohen.com
• Phone: 516-615-0160

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Magic Angle Direction Imaging for ACL tears and meniscus injuries

  This study tries a new low-field MRI technique called Magic Angle Direction Imaging to see if it shows ACL tears and meniscus injuries more clearly in adults scheduled for ligament repair.

  Recruiting at 2 sites Imperial College London · London and 1 other locations · NCT07366619

• Anti-gravity treadmill for meniscus tear rehabilitation

  This test will see if walking on an anti-gravity treadmill helps adults 18–40 with MRI-confirmed meniscus tears reduce pain and improve knee function more than a conventional treadmill or standard rehab.

  Recruiting Bezmialem Vakif University · Istanbul, Eyup · NCT06646536

• Repairing longitudinal meniscus tears using fibrin clots

  This study is testing if using a special treatment called fibrin clots during surgery can help people with meniscus tears heal better than the usual repair methods.

  Recruiting at 2 sites Ankara City Hospital Bilkent · Ankara and 1 other locations · NCT06541756

• Effects of exercise on knee cartilage and function in people with meniscus tears

  This study tests whether progressive resistance exercises or aerobic exercises can improve knee cartilage health and function in people aged 35-55 with meniscus tears.

  Recruiting at 2 sites Jordan University of Science and Technology · Ar Ramtha and 1 other locations · NCT06532851

• Assessment of meniscal root tears treated with suture to the posterior cruciate ligament

  This study tests a new surgical method for fixing meniscal root tears in the knee to see if it helps patients recover better and avoid future problems like arthritis.

  Recruiting Istituto Ortopedico Rizzoli · Bologna · NCT06507241

• Using a collagen implant to enhance meniscus repair in the knee

  This study is testing if a special collagen implant can help people heal better after surgery for a torn meniscus in the knee compared to standard repair methods.

  Recruiting NYU Langone Health · New York, New York · NCT06041763

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.