Comparing a new bioactive sleeve to a placebo for pain relief after meniscus surgery

The Effect of a Novel Bioactive Sleeve on Postoperative Pain and Patient Reported Outcome Scores After Arthroscopic Meniscectomy and Meniscus Repairs: A Randomized Placebo Controlled Study

NA · Northwell Health · NCT06041321

This study is testing a new pain-relief sleeve after meniscus surgery to see if it helps patients recover better than a fake sleeve.

Quick facts

PhaseNA
Study typeInterventional
Enrollment100 (estimated)
Ages18 Years to 89 Years
SexAll
SponsorNorthwell Health (other)
Locations1 site (Woodbury, New York)
Trial IDNCT06041321 on ClinicalTrials.gov

What this trial studies

This clinical trial evaluates the effectiveness of a novel bioactive sleeve designed to reduce pain and improve recovery outcomes after meniscus surgery. It is a blinded randomized prospective study involving approximately 100 patients who will be assigned to receive either the bioactive sleeve or a placebo sleeve that looks and feels similar. The study will assess various patient-reported outcomes and physical therapy metrics at multiple time points post-surgery to determine the sleeve's impact on healing and pain management.

Who should consider this trial

Good fit: Ideal candidates are adults over 18 years old, in good health, and scheduled for meniscectomy or meniscus repair with a BMI under the 45th percentile.

Not a fit: Patients with a BMI over 40, severe knee osteoarthritis, or a history of autoimmune or vascular diseases may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved pain management and faster recovery for patients undergoing meniscus surgery.

How similar studies have performed: While this approach is innovative, similar studies have shown promise in using bioactive materials for postoperative recovery, suggesting potential for success.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Provision of signed and dated informed consent form
* Stated willingness to comply with all study procedures and availability for the duration of the study
* Male or female, over the age of 18, undergoing a meniscectomy or meniscus repair
* In good general health as evidenced by medical history
* Under 45th percentile BMI
* Willing to adhere to the study intervention regimenregimen.
* Kellgren-Lawrence grade 2 or less

Exclusion Criteria:

* Febrile illness within 3 months
* BMI over 40
* Treatment with another investigational drug or other intervention within 6 months
* Kellgren-Lawrence grade 3 or more or 4
* History of autoimmune disease, circulatory disease, or vascular disorder

Where this trial is running

Woodbury, New York

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Meniscus Tear

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.