Breast Artery Calcification and Heart Health in Women
Official title: Risk Stratification for Asymptomatic Women With Incidentally Found Breast Artery Calcification on Their Routine Screening Mammogram
Run by Northwell Health · NCT07809932 · Data updated 2026-11-12
This study tests whether a breast artery calcification finding on a mammogram is linked to different cardiovascular markers in women 55–65 who do or do not have BAC.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 55 Years to 65 Years |
| Sex | Women only |
| Enrollment | 200 (estimated) |
| Sponsor | Northwell Health Academic / other |
| Locations | 1 site (Manhasset, New York) |
| Status | Recruiting |
| Started | July 31, 2026 |
| Main results expected | August 2027 |
| Study ends | August 2027 |
| Registry record updated | September 9, 2026 |
| Trial ID | NCT07809932 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are women aged 55–65 who have had a recent mammogram and have BAC reported as present or absent, with no history of cardiovascular disease or diabetes and not on statins.
✕Probably not a fit
Women with established cardiovascular disease, diabetes, or current statin use are not eligible and may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
The study compares two groups of women aged 55–65 who recently had mammograms: those with BAC and those without. Participants provide fasting blood samples, undergo a cardiac CT scan, and complete two short questionnaires. Results will be shared with participants, and researchers will analyze how BAC relates to cardiovascular markers and risk. The goal is to understand how to manage women with incidental BAC findings in a way similar to how a cardiologist might approach care for asymptomatic patients. This is a prospective, two-cohort study conducted at Northwell Health facilities.
Why it matters
Potential benefit: If successful, the study could help clinicians interpret BAC findings and tailor cardiovascular risk management for women who screen positive for BAC.
How similar studies have gone: Previous work has linked incidental BAC to future cardiovascular events, but this study tests a structured management approach in a prospective, two-cohort design.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * female * 55-65 years old Exclusion Criteria: * ischemia * diabetes * statin or cholesterol lowering medicine use * cardiovascular disease: coronary artery disease, heart failure, arrhythmia, significant valvular disease * history of breast surgery or breast cancer * pregnant women * breastfeeding women * women unable to consent
Where it's running
-
North Shore University Hospital
Manhasset, New York, United States Recruiting
Study contacts
- Principal investigator: Nisha Parikh, MD, MPH — Northwell Health
- Study coordinator: Thara Ali, MD
- Email: Tali7@northwell.edu
- Phone: 917-951-8945
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
Cardiovascular effects of gender-affirming hormones in adults
This project tests whether masculinizing or feminizing gender-affirming hormone therapy changes heart and blood vessel health in transgender adults who have been on hormones for at least 12 months.
-
Air filters at home to see if breathing cleaner air helps heart health in obesity
This study tests whether portable air filtration systems can improve cardiovascular risk factors in adults with obesity and high blood pressure.
-
Bringing preventive cardiovascular care to Indigenous and remote communities
This project tests a mobile health unit to screen and provide culturally safe cardiovascular and metabolic care for Indigenous and remote communities in Canada.
-
Longevity Metrics AI/ML Development Study
Researchers are testing AI models that score health screening tests and predict outcomes like life expectancy for adults, using ongoing follow-up data.
-
Oxidative Stress and Heart Risk in People with Rheumatoid Arthritis
This study tests whether certain markers of oxidative stress in people with rheumatoid arthritis are linked to subclinical atherosclerosis and arterial stiffness, which could relate to future heart disease risk.
-
Work-Related Frustration and Higher Blood Pressure Risk in Everyday Adults
This observational study tests whether stress and frustration at work relate to blood pressure patterns that signal higher cardiovascular risk among adults aged 40–65 who are working and have no prior cardiovascular disease or blood pressure treatment.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.