SMART goals program for youth with prediabetes

Impact of SMART GOAL Setting Protocol on Body Weight and Metabolic Parameters in Children and Adolescents With Prediabetes; a Randomized Clinical Trial.

Not applicable Interventional Northwell Health · NCT06067451

This study is testing if a special goal-setting program can help overweight kids with prediabetes lose weight and improve their health compared to regular care.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment80 (estimated)
Ages10 Years to 18 Years
SexAll
SponsorNorthwell Health Academic / other
Locations2 sites (New York, New York and 1 other locations)
Trial IDNCT06067451 on ClinicalTrials.gov

What this trial studies

This study aims to evaluate the effectiveness of a SMART goal-setting protocol in reducing body weight and improving metabolic parameters in obese children with prediabetes. Participants will be randomized to either receive the SMART Goal Setting Protocol or standard care, with both groups receiving consistent medical nutrition therapy. The study will assess changes in BMI Z-score, hemoglobin A1c, and lipid levels over a six-month period. By empowering children to set their own health goals, the study seeks to enhance motivation and engagement in managing their condition.

Who should consider this trial

Good fit: Ideal candidates are children aged 10-18 years with a BMI at or above the 85th percentile and hemoglobin A1c levels between 5.7% and 6.4%.

Not a fit: Patients who are not interested in weight loss or lifestyle changes, or those with existing diabetes or certain psychiatric disorders, may not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could lead to significant improvements in weight management and metabolic health for children at risk of type 2 diabetes.

How similar studies have performed: Previous studies have shown promise in using goal-setting strategies for behavior change in pediatric populations, indicating potential success for this approach.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

1. Children between ages 10-18 years at baseline visit
2. Children with BMI for age and sex ≥ 85th percentile at baseline visit
3. Children with hemoglobin A1c 5.7% to 6.4% at baseline visit

Exclusion Criteria:

1. Children who are not able to provide assent to the study
2. Children less than 10 years in age
3. Children that are not interested in weight loss or diet and lifestyle change
4. Children with known diabetes that use medications that alter glucose or lipid metabolism such as (insulin, metformin, Glucagon Like Peptide-1 Receptor Antagonist (GLP-1 RA), Statins, Accutane).
5. Children on medications that can alter body weight (including antidepressants, steroids, stimulants).
6. Children with documented learning and/or intellectual disabilities as identified through the electronic medical record (such as cognitive disability or autism spectrum disorder)
7. Children with known psychiatric disorders disabilities as identified through the electronic medical record (e.g., schizophrenia, depression, bipolar disorder, or psychosis
8. Children that have known medical conditions, including endocrine dysfunction, Cushing's Syndrome, or other systemic illness
9. Children with known or suspected eating disorders as identified through the electronic medical record
10. Children that have known genetic or syndromic obesity
11. Female children who are pregnant

Where this trial is running

New York, New York and 1 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions PreDiabetesAdolescent ObesityBehavior, HealthNutritional and Metabolic DiseasesDiet HabitLifestyle Risk ReductionNutrition
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.