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Clinical trials and research at National Heart Centre Singapore

• 14Clinical trials
• 7Countries

Newest trials

All recruiting trials (14)

• Cardiovascular and Cognitive Health Initiative

  This study tests whether targeted cognitive and heart-health interventions can help improve thinking skills in adults with cardiovascular disease.

  Recruiting National Heart Centre Singapore · Singapore and 3 other locations · NCT07829380

• SoniCracker intravascular lithotripsy for calcified coronary arteries

  This study will test whether the SoniCracker intravascular lithotripsy device can safely help open heavily calcified coronary arteries in adults having planned PCI.

  Recruiting National Heart Centre Singapore · Singapore · NCT07259239

• Asia‑Pacific registry of mitral and tricuspid valve‑in‑valve and valve‑in‑ring procedures

  Collecting medical data from adults across the Asia‑Pacific who have had—or plan to have—mitral or tricuspid valve‑in‑valve or valve‑in‑ring procedures with a balloon‑expandable valve to see how patients do.

  Recruiting National Heart Centre Singapore · New Lambton Heights and 7 other locations · NCT07058935

• Understanding genetic factors in young adults with heart attacks

  This study is trying to find out how genetics might play a role in heart attacks for young adults under 60 who don’t have typical heart disease risk factors.

  Recruiting National Heart Centre Singapore · Singapore · NCT06698341

• Imaging metabolic processes in the body using Carbon-13 pyruvate

  This study is testing a new type of MRI using a special substance to see if it can help us understand how the body processes energy in people with heart problems and healthy volunteers without using harmful radiation.

  Recruiting Phase 2 National Heart Centre Singapore · Singapore · NCT06645691

• Personalized interventions for older adults with cardiac frailty

  This study is testing personalized exercise and diet plans to see if they can help older adults with heart problems feel better and improve their health.

  Recruiting at 6 sites National Heart Centre Singapore · Singapore and 5 other locations · NCT05946174

• Exercise to slow down cardiovascular ageing

  This study tests if an exercise program can help older adults slow down heart aging and lower their risk of heart disease compared to those who don’t exercise.

  Recruiting National Heart Centre Singapore · Singapore, Singapore · NCT05775484

• Exploring the extremes of coronary artery disease

  This study is trying to find out why some people with coronary artery disease have serious issues despite not having common risk factors, while others with many risk factors have little to no disease, by looking at their genes and blood samples.

  Recruiting National Heart Centre Singapore · Singapore · NCT05775445

• AI platform for CT coronary angiography applications

  This study is testing a new AI platform that helps doctors quickly and accurately analyze heart scans for patients with coronary artery disease to improve their treatment and care.

  Recruiting at 3 sites National Heart Centre Singapore · Singapore and 2 other locations · NCT05509010

• Evaluating safety and effectiveness of a procedure for heavily calcified coronary lesions

  This study is testing if a special procedure called rotational atherectomy is safe and effective for people with heavily calcified coronary arteries who need a heart procedure.

  Recruiting at 2 sites National Heart Centre Singapore · Kitakyushu and 1 other locations · NCT04742478

• Preventing heart disease in high-risk diabetes patients

  This study is testing whether stronger medication for adults with type 2 diabetes and high heart disease risk can help prevent heart problems compared to regular treatment.

  Recruiting Phase 4 National Heart Centre Singapore · Singapore · NCT04286399

• Collecting biological samples and imaging data to study heart health and disease

  This study is collecting health information and samples from people with heart conditions and healthy volunteers to learn more about heart health and disease.

  Recruiting National Heart Centre Singapore · Singapore, Singapore · NCT02804269

• Impact of physical activity and blood pressure on heart health in healthy individuals

  This study is trying to see how physical activity and blood pressure affect heart health in healthy people to help improve heart care.

  Recruiting National Heart Centre Singapore · Singapore, Singapore · NCT02791152

• Understanding heart muscle response to high blood pressure

  This study looks at how high blood pressure affects the heart muscle in people with hypertension to see if certain heart changes can help improve treatment strategies.

  Recruiting National Heart Centre Singapore · Singapore · NCT02670031

Quick answers

How many clinical trials run by National Heart Centre Singapore are recruiting right now?

14, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 7 countries. The most sites are in Singapore (14 trials), Japan (1 trial), Australia (1 trial), Hong Kong (1 trial), India (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 4: 1, Phase 2: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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