AI platform for CT coronary angiography applications

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to develop an AI-driven national platform for CT coronary angiography that automates the processes of anonymization, reporting, Agatston scoring, and plaque quantification in patients with coronary artery disease (CAD). By leveraging artificial intelligence, the platform seeks to enhance diagnostic accuracy and efficiency, reducing the time required for report generation and minimizing inter-observer variability. The initiative addresses the growing prevalence of CAD and aims to improve clinical management and prognosis through better prediction of pharmacotherapy responses.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Age ≥21 years old
2. Signed informed consent
3. Clinically indicated for evaluation by CTCA

Exclusion Criteria:

1. Individuals unable to provide informed consent
2. Known complex congenital heart disease
3. Planned invasive angiography for reasons other than CAD
4. Non-cardiac illness with life expectancy \< 2 years
5. Pregnancy
6. Concomitant participation in another clinical trial in which subject is subject to investigational drug or device
7. Cardiac event and/or coronary revascularization (percutaneous coronary intervention (PCI) and/or coronary artery bypass grafting (CABG) and/or valvular repair/replacement prior to CTCA
8. Glomerular Filtration Rate ≤ 30mL/min
9. Known allergy to iodinated contrast agent
10. Contraindications to beta blockers or nitroglycerin or adenosine

Where it's running

• National Heart Centre Singapore
  Singapore, Singapore Recruiting
• National University Hospital
  Singapore, Singapore Recruiting
• Tan Tock Seng Hospital
  Singapore, Singapore Recruiting

Study contacts

• Principal investigator: Liang Zhong — National Heart Centre Singapore
• Study coordinator: Associate Professor Zhong Liang
• Email: zhong.liang@nhcs.com.sg
• Phone: +65 6704 2237

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.