Condition

Traumatic Brain Injury (TBI) Patients clinical trials and research

• 14Clinical trials
• 2New in 30 days
• 10Countries

Newest Traumatic Brain Injury (TBI) Patients clinical trials

All recruiting trials (14)

• Smartphone-based EEG to detect hidden awareness in ICU patients with brain injuries

  Researchers will test a smartphone-enabled EEG to see if it can reveal Cognitive Motor Dissociation in ICU patients who can’t show commands at bedside.

  Recruiting Columbia University · Miami, Florida and 8 other locations · NCT07917728

• Propranolol for Severe Traumatic Brain Injury in the ICU

  A randomized, triple-blind trial tests whether propranolol helps adults with moderate to severe TBI in the ICU.

  Recruiting at 5 sites Phase 3 Fundació d'investigació Sanitària de les Illes Balears · Palma de Mallorca, Balearic Islands and 5 other locations · NCT07899164

• Hyperbaric Oxygen Therapy for Veterans With TBI and PCS

  This study tests whether 40 HBOT sessions can change blood biomarkers in veterans with traumatic brain injury and persistent symptoms, and whether PTSD affects those biomarker changes.

  Recruiting Phase 2 Summit Hyperbarics and Wellness · Boise, Idaho · NCT07849465

• Sleep patterns to help predict waking from brain injury

  Doctors are testing whether brain activity during sleep can help predict when a person with a serious brain injury will regain awareness.

  Recruiting Columbia University · Miami, Florida and 1 other locations · NCT07794605

• Blue vs red fixation training for light sensitivity after brain injury

  Researchers test whether daily 20-minute blue-light fixation training helps people with light sensitivity after traumatic brain injury more than red-light fixation training.

  Recruiting Ohio State University · Columbus, Ohio · NCT07606300

• SeeMe: automated facial and hand tracking to reveal hidden responses after traumatic brain injury

  This project tests whether a high-resolution camera system with AI can detect very small, voluntary facial and hand movements in adults with severe traumatic brain injury who appear unresponsive.

  Recruiting Stony Brook University · Stony Brook, New York · NCT07560631

• Using a portable VR headset to measure pupil reactions for diagnosing and monitoring head injury

  This research tests whether a VR headset that flashes brief, gentle colored lights can detect and track traumatic brain injury by measuring how the pupil responds in people with TBI, similar non-TBI trauma patients, and healthy adults.

  Recruiting Sheba Medical Center · Tel HaShomer, Tel Aviv (Gosh Dan) · NCT07474987

• Metabolomic profiling to find blood markers for severe traumatic brain injury

  This project will test whether patterns of small molecules in the blood can distinguish adults with severe TBI from injured patients without brain injury.

  Recruiting Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital · Aksaray, Ankara · NCT07292766

• Vitamin D3 to help recovery after mild-to-moderate traumatic brain injury

  This trial will test whether a short course of vitamin D3 helps adults (18–65) recover better and reduce inflammation after mild-to-moderate traumatic brain injury.

  Recruiting Phase 2 Lagos State University · Lagos · NCT07269457

• Preventing early seizures after traumatic brain injury

  This randomized study will test whether phenytoin, levetiracetam, or placebo best prevent early seizures in people hospitalized with moderate-to-severe traumatic brain injury.

  Recruiting at 3 sites Phase 4 All India Institute of Medical Sciences, Jodhpur · Chandigarh, Punjab and 2 other locations · NCT07072624

• Saline versus balanced crystalloid fluids for moderate-to-severe traumatic brain injury

  This will test whether giving saline or a balanced crystalloid fluid to people with moderate-to-severe traumatic brain injury leads to better recovery.

  Recruiting Phase 3 University of Louisville · Louisville, Kentucky · NCT06953674

• Using a prosthetic to prevent complications after skull surgery

  This study is testing if a special helmet can help people who had skull surgery avoid complications and recover better.

  Recruiting at 2 sites Johns Hopkins University · Baltimore, Maryland and 1 other locations · NCT06899711

• Using brain stimulation to improve cognitive recovery in traumatic brain injury

  This study is testing if a type of brain stimulation can help improve thinking skills in people with moderate to severe traumatic brain injury.

  Recruiting University of Cincinnati · Cincinnati, Ohio · NCT06871124

• Enhanced environment therapy for recovery in chronic traumatic brain injury

  This study tests if a new therapy program where people with chronic traumatic brain injury run a café can help them improve their thinking, social, and movement skills better than regular treatment.

  Recruiting MetroHealth Medical Center · Cleveland, Ohio · NCT06734026

Related topics

Quick answers

How many Traumatic Brain Injury (TBI) Patients clinical trials are recruiting right now?

14, as of November 12, 2026. 2 of them were first registered in the last 30 days. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 10 countries. The most sites are in United States (9 trials), Israel (1 trial), Nigeria (1 trial), Turkey (Türkiye) (1 trial), India (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 2, Phase 3: 2, Phase 4: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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