Condition

Severe Traumatic Brain Injury clinical trials and research

• 7Clinical trials
• 10Countries

Newest Severe Traumatic Brain Injury clinical trials

All recruiting trials (7)

• Dual-Site Ear Nerve Stimulation for Severe Brain Injury-Related Coma

  This study tests a gentle, non-invasive stimulation on the left ear to try to help some people in coma due to severe traumatic brain injury regain awareness.

  Recruiting Stony Brook University · Stony Brook, New York · NCT07719595

• Neutral fluid balance in adults with traumatic brain injury (LIMIT-TBI)

  This study tests whether keeping daily fluid balance around zero (within 500 mL) for the first 5 days in the ICU is feasible and safe for adults with traumatic brain injury.

  Recruiting at 3 sites Phase 2 Erasme University Hospital · Brussels and 2 other locations · NCT07625995

• SeeMe: automated facial and hand tracking to reveal hidden responses after traumatic brain injury

  This project tests whether a high-resolution camera system with AI can detect very small, voluntary facial and hand movements in adults with severe traumatic brain injury who appear unresponsive.

  Recruiting Stony Brook University · Stony Brook, New York · NCT07560631

• Prognostic model for neurocritical patients using multimodal brain monitoring

  This study tests a model that uses EEG, TCD, and NIRS data to predict 90-day outcomes (awake, coma, or death) in adults with acute brain injuries in intensive care.

  Recruiting Xiangya Hospital of Central South University · Changsha, Hunan · NCT07115459

• Understanding cerebral vasospasm in traumatic brain injury with subarachnoid hemorrhage

  This study is testing how common and serious blood vessel narrowing in the brain is for adults with moderate to severe traumatic brain injuries and bleeding, to see if better scans can help improve their care.

  Recruiting University Hospital Center of Martinique · Fort-de-France · NCT06560372

• Using external lumbar drainage to lower brain pressure in severe traumatic brain injury

  This study is testing if using a special drainage method can safely lower brain pressure in people with severe traumatic brain injuries while they receive standard care.

  Recruiting at 6 sites Brain Trauma Foundation · Gainesville, Florida and 5 other locations · NCT05889650

• Trial of Intracranial Pressure Monitoring in Pediatric Severe Traumatic Brain Injury

  This study tests if using a special monitor to check brain pressure helps children with severe brain injuries recover better than just relying on scans and exams.

  Recruiting at 10 sites University of Washington · Seattle, Washington and 10 other locations · NCT05566431

Related topics

Quick answers

How many Severe Traumatic Brain Injury clinical trials are recruiting right now?

7, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 10 countries. The most sites are in United States (4 trials), France (1 trial), China (1 trial), Belgium (1 trial), Italy (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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