Condition

Sepsis, Severe clinical trials and research

• 10Clinical trials
• 6Countries

Newest Sepsis, Severe clinical trials

All recruiting trials (10)

• Investigating how transposable elements affect immune aging in sepsis patients

  This study looks at how certain genetic elements might affect the immune system and health outcomes in people with sepsis in the ICU.

  Recruiting University of California, San Francisco · San Francisco, California · NCT06809868

• Identifying biomarkers for diagnosing sepsis in the emergency room

  This study is trying to find out if certain immune responses can help doctors spot sepsis in patients with infections when they arrive at the emergency room.

  Recruiting at 2 sites Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) · Almere Stad, Flevoland and 2 other locations · NCT06178822

• Reducing unnecessary vancomycin use in children with suspected sepsis

  This study is testing a new approach to see if better guidelines and education can help doctors use less vancomycin in children suspected of having sepsis, which could lower the risk of kidney problems.

  Recruiting at 4 sites Children's Hospital of Philadelphia · Atlanta, Georgia and 3 other locations · NCT05975671

• Early use of norepinephrine for treating severe sepsis

  This study is testing if giving norepinephrine earlier can help people with severe sepsis feel better and live longer compared to a placebo.

  Recruiting Phase 4 Tunis University · Tunis · NCT05836272

• Evaluating sepsis treatment methods in emergency departments

  This study tests two different treatment plans for sepsis in emergency rooms to see which one helps patients survive and avoid breathing problems better.

  Recruiting Rhode Island Hospital · Providence, Rhode Island · NCT05491941

• Treatment for severe sepsis using immune cell therapy

  This study tests a new immune cell therapy for adults with severe sepsis to see if it can help them recover better alongside standard treatment.

  Recruiting at 18 sites Phase 2 Artcline GmbH · Freiburg im Breisgau, Baden-Wurttemberg and 19 other locations · NCT05442710

• Using gamma globulin to treat critically ill children with inflammatory storms

  This study is testing if gamma globulin therapy can help critically ill children with severe inflammatory conditions recover better than those who don’t receive it.

  Recruiting at 2 sites Children's Hospital of Fudan University · Shanghai, Shanghai Municipality and 1 other locations · NCT04850456

• Personalized care approach for patients with suspected sepsis

  This study is testing new ways to diagnose sepsis in about 1500 adults who show signs of it when they arrive at the emergency department, to help create more personalized treatment plans.

  Recruiting Oslo University Hospital · Oslo · NCT04203979

• Using BIS monitoring to assess sepsis severity in critically ill patients

  This study tests if using a special brain monitoring tool can help doctors understand how severe sepsis is in critically ill patients.

  Recruiting Suez Canal University · Dalian, Dalian · NCT03244293

• Examining Monocyte Profiles in Critically Ill Patients with Pseudomonas Aeruginosa Sepsis

  This study is trying to see if the type of immune cells in the blood of critically ill patients with sepsis from Pseudomonas aeruginosa can tell us more about how sick they are and how they might recover.

  Recruiting University of Ulm · Ulm · NCT03044223

Related topics

Quick answers

How many Sepsis, Severe clinical trials are recruiting right now?

10, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 6 countries. The most sites are in United States (3 trials), Germany (2 trials), China (2 trials), Norway (1 trial), Tunisia (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 1, Phase 4: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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