Using BIS monitoring to assess sepsis severity in critically ill patients

Sensitivity and Specificity of Bispectral Index (BIS) for Classification of Procalcitonin (PCT) Sepsis Grades in Critically Ill Patients With Sepsis, Severe Sepsis and Septic Shock and Multiple Organ Failure (MOF)

Observational Suez Canal University · NCT03244293

This study tests if using a special brain monitoring tool can help doctors understand how severe sepsis is in critically ill patients.

Quick facts

Study typeObservational
Enrollment20 (estimated)
SexAll
SponsorSuez Canal University Academic / other
Locations1 site (Dalian, Dalian)
Trial IDNCT03244293 on ClinicalTrials.gov

What this trial studies

This observational study evaluates the effectiveness of Bispectral Index (BIS) monitoring in classifying the severity of sepsis in critically ill patients. It aims to correlate BIS values with procalcitonin (PCT) graded sepsis levels and other clinical parameters such as C-reactive protein, Glasgow coma scale, and sequential organ failure assessment scores. The study involves measuring BIS values over time to monitor changes in the patient's mental state and sepsis condition. No interventions are administered, as the focus is on observational data collection.

Who should consider this trial

Good fit: Ideal candidates for this study are critically ill patients diagnosed with sepsis.

Not a fit: Patients who have received medications that interfere with BIS monitoring will not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could enhance the monitoring and management of sepsis in critically ill patients, potentially leading to better outcomes.

How similar studies have performed: While the use of BIS monitoring in sepsis is a novel approach, similar studies have shown promise in utilizing monitoring technologies for critical care assessments.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria: patients with sepsis

* patients with sepsis

Exclusion Criteria:

* Patients who received drugs that would interfere with BIS monitoring

Where this trial is running

Dalian, Dalian

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Sepsis, Severe
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.