Personalized care approach for patients with suspected sepsis
Sepsis: From Syndrome to Personalized Care
This study is testing new ways to diagnose sepsis in about 1500 adults who show signs of it when they arrive at the emergency department, to help create more personalized treatment plans.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 1950 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Oslo University Hospital Academic / other |
| Locations | 1 site (Oslo) |
| Trial ID | NCT04203979 on ClinicalTrials.gov |
What this trial studies
This observational study aims to evaluate the effectiveness of various biomarkers and molecular biological methods in diagnosing sepsis among patients admitted to the emergency department. It will include approximately 1500 adult patients who are suspected of having sepsis and are managed by specialized rapid response teams. The study will also focus on identifying novel sepsis endotypes to enhance personalized treatment strategies. Informed consent will be obtained from participants, and the study will take place over a three-year period.
Who should consider this trial
Good fit: Ideal candidates for this study are adults over 18 years old who are admitted to the emergency department with suspected sepsis.
Not a fit: Patients who are unable to provide informed consent or have conditions other than sepsis will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to more accurate and personalized treatment options for patients with sepsis.
How similar studies have performed: Other studies have shown promise in using biomarkers for sepsis diagnosis, but this approach of identifying novel endotypes is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * admitted to emergency department OUH, Ullevål. * managed by the medical rapid response team or the sepsis rapid response team Exclusion Criteria: * Not given informed consent by patient or next of kin (if patient is not able to)
Where this trial is running
Oslo
- Oslo University Hospital — Oslo, Norway (Recruiting)
Study contacts
- Principal investigator: Aleksander R Holten, PhD — Oslo University Hospital
- Study coordinator: Aleksander R Holten, PhD
- Email: aleksander.holten@gmail.com
- Phone: +4799275784
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.