Condition

Rotator Cuff Tears clinical trials and research

• 28Clinical trials
• 13NIH research projects
• 1New in 30 days
• 11Countries

Newest Rotator Cuff Tears clinical trials

All recruiting trials (28)

• Rotator cuff repair with biceps rerouting and dermal graft augmentation for large, difficult tears

  This study tests a combined surgical approach to see if it helps tendon retear rates in adults with large rotator cuff tears that are hard to repair.

  Recruiting Tam Anh Research Institute · Ho Chi Minh City, Ho Chi Minh · NCT07875556

• Biomarkers to see if rotator cuff repairs will heal after surgery

  This study tests whether biomarkers in shoulder tissue and synovial fluid can predict whether a rotator cuff repair will heal, using MRI after surgery to compare those who heal with those who don’t.

  Recruiting University of Iowa · Iowa City, Iowa · NCT07781553

• Mobilization with Movement for people with rotator cuff lesions

  This trial will test whether Mobilization with Movement helps reduce pain, improve shoulder function, and restore joint position sense in adults with rotator cuff lesions.

  Recruiting Kirsehir Ahi Evran Universitesi · Kırşehir · NCT07383038

• Does age-related muscle loss change rotator cuff tear patterns?

  We will see if age-related muscle loss (sarcopenia) is linked to the location and type of rotator cuff tears in adults aged 40–75 with rotator cuff syndrome.

  Recruiting Haydarpasa Numune Training and Research Hospital · Istanbul, Üsküdar · NCT07183774

• Impact of neck nerve compression (cervical radiculopathy) on recovery after rotator cuff repair

  This study sees if people under 65 who had cervical radiculopathy before rotator cuff repair have different shoulder function and quality of life after surgery compared with those who did not.

  Recruiting Biruni University · Istanbul, Istanbul · NCT07001566

• Using virtual reality to help rehabilitate shoulder injuries

  This study tests whether using virtual reality can make shoulder rehabilitation more engaging and effective for people with shoulder injuries.

  Recruiting La Tour Hospital · Meyrin, Canton of Geneva · NCT06963983

• FiberLocker® augmentation for rotator cuff repair

  This study will test whether adding the FiberLocker® System (SpeedPatch® PET plus FiberLocker® Instrument) to arthroscopic repair improves healing and shoulder function in adults 30–70 with full-thickness rotator cuff tears of at least 2 cm.

  Recruiting at 4 sites ZuriMED Technologies Inc. · Chicago, Illinois and 3 other locations · NCT06918041

• Motor imagery training for pain and function in partial rotator cuff tears

  This study tests if motor imagery training can help people with partial rotator cuff tears feel less pain and improve their shoulder function compared to traditional physiotherapy.

  Recruiting Kutahya Health Sciences University · Kütahya · NCT06875895

• Comparing tuberoplasty and balloon spacer for rotator cuff tears

  This study is testing whether a new shoulder procedure called tuberoplasty works better than a balloon spacer for people with large, irreparable rotator cuff tears to see how it affects their pain and ability to move their arm.

  Recruiting Phase 1/2 University of Minnesota · Minneapolis, Minnesota · NCT06735170

• Using Band Connect to improve physical therapy for shoulder surgeries

  This study is testing if using the Band Connect platform can help people recovering from shoulder surgery stick to their exercise programs and feel more satisfied with their recovery.

  Recruiting University Hospitals Cleveland Medical Center · Cleveland, Ohio · NCT06733480

• Rotator cuff repair with BioEnthesis augmentation vs without augmentation

  This trial tests whether adding BioEnthesis to rotator cuff repair helps healing in adults with a reparable tear.

  Recruiting at 5 sites Phase 4 Brooke Army Medical Center · Air Force Academy, Colorado and 4 other locations · NCT06289686

• Comparing two methods for repairing rotator cuff tears

  This study is testing whether using a synthetic patch during rotator cuff surgery helps people heal better and reduces the chance of their tear coming back compared to standard surgery.

  Recruiting Spital Thurgau AG · Frauenfeld, Thurgau · NCT06076902

• Comparing two methods for repairing rotator cuff tears using BioBrace®

  This study is testing if using BioBrace® for repairing large rotator cuff tears helps patients recover better and feel stronger compared to traditional repair methods.

  Recruiting Nova Scotia Health Authority · Halifax, Nova Scotia · NCT05959733

• Comparing two surgical techniques for massive rotator cuff tears

  This study is testing which of two surgical methods works better for people with large, irreparable rotator cuff tears to see how they affect recovery and quality of life.

  Recruiting Nova Scotia Health Authority · Halifax, Nova Scotia · NCT05925881

• Pitch-Patch Rotator Cuff Augmentation: Post-Market Follow-Up

  This study follows patients who received the Pitch-Patch to reinforce partially repairable rotator cuff tears to see how well it performs and stays safe over the long term.

  Recruiting Xiros Ltd · Reading · NCT05906004

• Comparing a new graft to standard care for rotator cuff repair

  This study tests if a new graft can help people heal better and regain shoulder function after rotator cuff repair surgery compared to standard treatment.

  Recruiting The University of Texas Health Science Center, Houston · Houston, Texas · NCT05894265

• Using acellular dermal matrix to enhance repair of massive rotator cuff tears

  This study is testing if using a special skin-based material during surgery can help people with large rotator cuff tears heal better and recover faster.

  Recruiting Istituto Ortopedico Rizzoli · Bologna, BO · NCT05855759

• Comparing two treatments for massive rotator cuff tears

  This study is testing which treatment, reverse shoulder surgery or shoulder repair, works better for older patients with severe rotator cuff tears that didn't get better with other methods.

  Recruiting at 2 sites La Tour Hospital · Portland, Oregon and 1 other locations · NCT05807854

• Microfracture technique to improve healing of rotator cuff tears

  This study tests if a new microfracture technique can help people with medium to large rotator cuff tears heal better after surgery compared to standard repair methods.

  Recruiting Affiliated Hospital of Nantong University · Nantong, Jiangsu and 1 other locations · NCT05624164

• Long-term follow-up on shoulder arthroplasty outcomes

  This study is looking at how well shoulder replacement surgery works over time by following patients for at least 10 years to see how they feel and how their shoulders are doing.

  Recruiting at 40 sites Exactech · Laguna Woods, California and 39 other locations · NCT05603728

• Comparing slow and accelerated rehabilitation after shoulder surgery

  This study is testing whether a slower or faster rehabilitation program after shoulder surgery helps people with severe rotator cuff tears recover better.

  Recruiting Hacettepe University · Kırşehir · NCT05450510

• Bioinductive patch for repairing rotator cuff tears

  This study is testing if adding a special patch during surgery can help people with rotator cuff tears heal better than just standard surgery alone.

  Recruiting Phase 4 Henry Ford Health System · Detroit, Michigan · NCT05439850

• Accelerated rehabilitation for rotator cuff tears using the InSpace device

  This study is testing two different rehab programs for people with serious rotator cuff tears who have had surgery using the InSpace device to see which one helps them recover better.

  Recruiting at 11 sites Stryker Endoscopy · Phoenix, Arizona and 10 other locations · NCT05329584

• Using a mobile app for self-rehabilitation after rotator cuff surgery

  This study tests if using a mobile app for rehabilitation after rotator cuff surgery can help patients recover as well as traditional in-person therapy.

  Recruiting Kaohsiung Veterans General Hospital. · Kaohsiung City · NCT05102968

• Repairing rotator cuff tears with or without a dermal patch

  This study is testing whether using a special dermal patch during rotator cuff surgery helps people aged 50 to 75 heal better than traditional repair methods.

  Recruiting Phase 4 University Hospitals, Leicester · Leicester · NCT04975581

• Hormone therapy to improve healing after shoulder surgery

  This study tests if hormone therapy can help men with low hormone levels heal better after shoulder surgery.

  Recruiting Phase 2 University of Utah · Salt Lake City, Utah · NCT04944836

• Genetic study of rotator cuff tears

  This study is testing whether certain genes can increase the risk of rotator cuff tears in people by comparing those with tears to those without.

  Recruiting at 3 sites University of Michigan · Iowa City, Iowa and 9 other locations · NCT04831164

• Evaluating hemidiaphragmatic paralysis after shoulder surgery with nerve blocks

  This study is testing how often patients having shoulder surgery with a specific nerve block experience breathing issues and how it affects their pain and use of pain medication afterward.

  Recruiting Duke University · Durham, North Carolina · NCT04209504

NIH-funded research (13)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Meltblown scaffolds to help irreparable rotator cuff tears

  A new 3-D biomaterial scaffold made from meltblown technology aims to improve interposition grafts for people with irreparable rotator cuff tears.

  NIH research Purdue University · West Lafayette, United States · NIH-11628894

• Predicting How Exercise Helpful Rotator Cuff Tears Will Turn Out

  Aimed at people with rotator cuff tears, the grant investigates how a personalized exercise program might lead to better shoulder function and fewer surgeries.

  NIH research University of Pittsburgh at Pittsburgh · Pittsburgh, United States · NIH-11401081

• Nervous system role in recovering from painful rotator cuff tears

  This project looks at how brain and nervous system factors influence recovery and pain after rotator cuff tears to help tailor treatments for people suffering from this condition.

  NIH research University of Florida · Gainesville, United States · NIH-11345977

• Turning harmful shoulder fat into healing beige fat with targeted nanomedicine

  This project uses tiny medicine-filled nanoparticles to turn the harmful fat that builds up in torn shoulder muscles into healing, energy-burning fat to help people recover after rotator cuff tears.

  NIH research University of Texas San Antonio · San Antonio, United States · NIH-11340501

• Biomusculoskeletal drivers of shoulder pain in rotator cuff tears

  A research project will explore why some people with a torn rotator cuff have pain and others don’t by looking at nerves, brain signals, and shoulder muscle control.

  NIH research University of Florida · Gainesville, United States · NIH-11333838

• Genetic links to rotator cuff tears and muscle fatty change

  This project looks for genetic differences that raise the risk of rotator cuff tears, lead to fatty changes in shoulder muscles, and influence outcomes after surgery or physical therapy for people with atraumatic rotator cuff tears.

  NIH research University of Michigan at Ann Arbor · Ann Arbor, United States · NIH-11184504

• Who will benefit from shoulder exercise therapy for rotator cuff tears

  This project aims to find which people with rotator cuff tears do well with personalized exercise-based shoulder therapy.

  NIH research University of Pittsburgh at Pittsburgh · Pittsburgh, United States · NIH-11169004

• Investigating the genetic factors behind rotator cuff tears

  This study is looking at how our genes might affect the chances of getting rotator cuff tears in the shoulder and how well different treatments, like surgery or physical therapy, work for people with this condition. If you have a rotator cuff tear and are interested in how genetics and other factors like weight might p

  NIH research University of Michigan at Ann Arbor · Ann Arbor, United States · NIH-11142023

• Investigating genetic and therapeutic methods to improve recovery from severe shoulder injuries.

  This study is looking at how certain cells in your shoulder muscles behave after a big rotator cuff tear, which can make recovery harder, and it aims to find new ways to help people heal better from these injuries.

  NIH research Duke University · Durham, United States · NIH-11126625

• Understanding symptoms and joint health in people with rotator cuff tears

  This study is looking into why some people with rotator cuff tears feel pain while others don’t, and it’s for anyone interested in understanding how different factors, like nerves and mental well-being, can affect these symptoms.

  NIH research University of Florida · Gainesville, United States · NIH-11122332

• How the nervous system affects recovery from painful shoulder injuries.

  This study is looking at how the nervous system affects recovery for people with rotator cuff tears, to help figure out which patients might get the most relief from certain pain treatments.

  NIH research University of Florida · Gainesville, United States · NIH-11084468

• Investigating the genetics behind rotator cuff tears.

  This study is looking at how your genes might affect your chances of getting a rotator cuff tear in your shoulder, and if you join, you’ll help researchers find out more about this so they can improve prevention and treatment for people at risk.

  NIH research University of Michigan at Ann Arbor · Ann Arbor, United States · NIH-10755631

• Using MRI to understand muscle degeneration in rotator cuff injuries

  This study is looking at how MRI and spectroscopy can help doctors see changes in muscles for people with rotator cuff tears, so they can better understand the injury and find out how well treatments are working, all without needing any invasive procedures.

  NIH research University of Florida · Gainesville, United States · NIH-10478830

Related topics

Quick answers

How many Rotator Cuff Tears clinical trials are recruiting right now?

28, as of November 12, 2026. 1 of them was first registered in the last 30 days. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 11 countries. The most sites are in United States (13 trials), Turkey (Türkiye) (5 trials), United Kingdom (3 trials), Canada (3 trials), Switzerland (3 trials). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 4: 3, Phase 1/2: 1, Phase 2: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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