Does age-related muscle loss change rotator cuff tear patterns?
Does Sarcopenia Influence Rotator Cuff Tear Patterns? Radiological Insights From Patients With Rotator Cuff Syndrome
We will see if age-related muscle loss (sarcopenia) is linked to the location and type of rotator cuff tears in adults aged 40–75 with rotator cuff syndrome.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 104 (estimated) |
| Ages | 40 Years to 75 Years |
| Sex | All |
| Sponsor | Haydarpasa Numune Training and Research Hospital Academic / other |
| Locations | 1 site (Istanbul, Üsküdar) |
| Trial ID | NCT07183774 on ClinicalTrials.gov |
What this trial studies
This is an observational, single-center study of adults 40–75 who present with at least three months of shoulder pain and a clinical diagnosis of rotator cuff syndrome and who have had shoulder MRI. Demographic and pain/function data (Visual Analog Scale and Shoulder Disability Questionnaire) will be collected, and rotator cuff tear location and type will be determined from imaging. A blinded clinician will measure sarcopenia using the STAR (Sonographic Thigh Adjustment Ratio) method combined with gait speed, handgrip strength, and the five-repetition chair stand test. The study will correlate sarcopenia measures with MRI-defined tear patterns to see if muscle loss predicts tear location or type.
Who should consider this trial
Good fit: Adults aged 40–75 with clinically diagnosed rotator cuff syndrome, at least three months of shoulder pain, and available shoulder MRI are ideal candidates.
Not a fit: People with prior shoulder surgery, other shoulder pathologies, recent hip/thigh surgery, neurologic disease, active cancer, cognitive impairment, or who are bedridden or wheelchair-bound are excluded and unlikely to benefit from this study's findings.
Why it matters
Potential benefit: If a link is found, clinicians could use sarcopenia screening to better predict tear patterns and tailor treatment or rehabilitation plans.
How similar studies have performed: Previous research has suggested sarcopenia is associated with worse shoulder outcomes and postoperative complications, but correlating sarcopenia via STAR with detailed MRI tear patterns is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Patients with rotator cuff syndrome 2. Aged between 40 and 75 years Exclusion Criteria: 1. History of previous shoulder surgery 2. Presence of shoulder pathology other than rotator cuff syndrome 3. History of surgical intervention involving the hip or thigh region 4. Being wheelchair-bound or bedridden 5. Presence of an oncologic disease 6. Diagnosis of any neurological disorder 7. Presence of cognitive impairment
Where this trial is running
Istanbul, Üsküdar
- Health Science University Haydarpaşa Numune Research and Training Hospital — Istanbul, Üsküdar, Turkey (Türkiye) (Recruiting)
Study contacts
- Study coordinator: sibel Suzen Ozbayrak, M.D.
- Email: sibels62@yahoo.com
- Phone: +90 506 343 81 87
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.