Does age-related muscle loss change rotator cuff tear patterns?
Official title: Does Sarcopenia Influence Rotator Cuff Tear Patterns? Radiological Insights From Patients With Rotator Cuff Syndrome
Run by Haydarpasa Numune Training and Research Hospital · NCT07183774 · Data updated 2026-11-12
We will see if age-related muscle loss (sarcopenia) is linked to the location and type of rotator cuff tears in adults aged 40–75 with rotator cuff syndrome.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 40 Years to 75 Years |
| Sex | All |
| Enrollment | 104 (estimated) |
| Sponsor | Haydarpasa Numune Training and Research Hospital Academic / other |
| Locations | 1 site (Istanbul, Üsküdar) |
| Status | Recruiting |
| Started | January 1, 2025 |
| Main results expected | December 1, 2025 |
| Study ends | December 30, 2025 |
| Registry record updated | November 26, 2025 |
| Trial ID | NCT07183774 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults aged 40–75 with clinically diagnosed rotator cuff syndrome, at least three months of shoulder pain, and available shoulder MRI are ideal candidates.
✕Probably not a fit
People with prior shoulder surgery, other shoulder pathologies, recent hip/thigh surgery, neurologic disease, active cancer, cognitive impairment, or who are bedridden or wheelchair-bound are excluded and unlikely to benefit from this study's findings.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This is an observational, single-center study of adults 40–75 who present with at least three months of shoulder pain and a clinical diagnosis of rotator cuff syndrome and who have had shoulder MRI. Demographic and pain/function data (Visual Analog Scale and Shoulder Disability Questionnaire) will be collected, and rotator cuff tear location and type will be determined from imaging. A blinded clinician will measure sarcopenia using the STAR (Sonographic Thigh Adjustment Ratio) method combined with gait speed, handgrip strength, and the five-repetition chair stand test. The study will correlate sarcopenia measures with MRI-defined tear patterns to see if muscle loss predicts tear location or type.
Why it matters
Potential benefit: If a link is found, clinicians could use sarcopenia screening to better predict tear patterns and tailor treatment or rehabilitation plans.
How similar studies have gone: Previous research has suggested sarcopenia is associated with worse shoulder outcomes and postoperative complications, but correlating sarcopenia via STAR with detailed MRI tear patterns is relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Patients with rotator cuff syndrome 2. Aged between 40 and 75 years Exclusion Criteria: 1. History of previous shoulder surgery 2. Presence of shoulder pathology other than rotator cuff syndrome 3. History of surgical intervention involving the hip or thigh region 4. Being wheelchair-bound or bedridden 5. Presence of an oncologic disease 6. Diagnosis of any neurological disorder 7. Presence of cognitive impairment
Where it's running
-
Health Science University Haydarpaşa Numune Research and Training Hospital
Istanbul, Üsküdar, Turkey (Türkiye) Recruiting
Study contacts
- Study coordinator: sibel Suzen Ozbayrak, M.D.
- Email: sibels62@yahoo.com
- Phone: +90 506 343 81 87
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.