Using MRI to understand muscle degeneration in rotator cuff injuries

Magnetic resonance biomarkers of muscle degeneration in patients with rotator cuff tears

['FUNDING_R21'] · UNIVERSITY OF FLORIDA · NIH-10478830

This study is looking at how MRI and spectroscopy can help doctors see changes in muscles for people with rotator cuff tears, so they can better understand the injury and find out how well treatments are working, all without needing any invasive procedures.

Quick facts

Phase['FUNDING_R21']
Study typeNih_funding
SexAll
SponsorUNIVERSITY OF FLORIDA (nih funded)
Locations1 site (GAINESVILLE, UNITED STATES)
Trial IDNIH-10478830 on ClinicalTrials.gov

What this research studies

This research investigates how magnetic resonance imaging (MRI) and spectroscopy can non-invasively assess muscle degeneration in patients with rotator cuff tears. By measuring changes in muscle tissue and function without the need for biopsies, the study aims to track disease progression and evaluate treatment effectiveness. The focus is on understanding the relationship between muscle microvascular function and overall muscle quality, which can help improve patient care. This innovative approach could lead to better management strategies for those suffering from rotator cuff injuries.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals diagnosed with rotator cuff tears who are experiencing muscle degeneration.

Not a fit: Patients without rotator cuff injuries or those with other unrelated musculoskeletal conditions may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved diagnostic and treatment options for patients with rotator cuff tears.

How similar studies have performed: Previous research has shown promise in using MRI techniques for assessing muscle conditions, indicating that this approach could be effective.

Where this research is happening

GAINESVILLE, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.