NIH-funded research R01 grant

Predicting How Exercise Helpful Rotator Cuff Tears Will Turn Out

Official title: Predicting the Outcome of Exercise Therapy for Treatment of Rotator Cuff Tears

Funded at University of Pittsburgh at Pittsburgh · NIH-11401081 · Data updated 2026-11-12

Aimed at people with rotator cuff tears, the grant investigates how a personalized exercise program might lead to better shoulder function and fewer surgeries.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Pittsburgh at Pittsburgh
NIH-funded
Lab location1 site (Pittsburgh, United States)
Project startSeptember 7, 2016
Project endAugust 31, 2027
Funding year2026
Award (this year)$575,193
NIH project number5R01AR069503-09
Project IDNIH-11401081 on NIH RePORTER

Who could benefit from this research

Could help

Adults with symptomatic isolated supraspinatus tears considering initial treatment options.

Less likely to help

Patients with tears unlikely to respond to exercise or with differing tear characteristics may not experience the same benefits.

What this research studies

This project builds on a prior cohort of patients with isolated supraspinatus tears who followed a personalized exercise therapy program. It uses patient-specific data and computer models to understand why some people improve with exercise while others need surgery. The researchers plan to analyze outcomes such as shoulder range of motion, strength, and patient-reported quality of life, and to link these outcomes with mechanistic factors from the models. The ultimate goal is to identify factors that predict who will benefit most from exercise therapy and when surgery might be necessary.

Why it matters

Potential benefit: If successful, patients with rotator cuff tears could receive more personalized treatment plans that reduce the need for surgery and improve recovery.

How similar studies have gone: Previous work showed low surgery rates and improved function with personalized exercise therapy, supporting further mechanistic and predictive studies.

Where this research is happening

  • University of Pittsburgh at Pittsburgh
    Pittsburgh, United States
    Active

Researchers

  • Principal investigator: Debski, Richard E — University of Pittsburgh at Pittsburgh
  • Study coordinator: Debski, Richard E

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.