Investigating the genetics behind rotator cuff tears.

The Genetic Epidemiology of Rotator Cuff Tears: the cuffGEN Study.

NIH-funded research University of Michigan at Ann Arbor · NIH-10755631

This study is looking at how your genes might affect your chances of getting a rotator cuff tear in your shoulder, and if you join, you’ll help researchers find out more about this so they can improve prevention and treatment for people at risk.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Michigan at Ann Arbor NIH-funded
Lab location1 site (Ann Arbor, United States)
Project IDNIH-10755631 on NIH RePORTER

What this research studies

This research focuses on understanding the genetic factors that contribute to rotator cuff tears, a common shoulder injury. By analyzing genetic data from participants, the study aims to identify specific genes and genetic variations associated with an increased risk of these injuries. Patients may be asked to provide genetic samples and health information to help researchers uncover patterns that could lead to better prevention and treatment strategies. The findings could ultimately enhance personalized care for individuals at risk of rotator cuff tears.

Who could benefit from this research

Good fit: Ideal candidates for this research include individuals with a history of rotator cuff tears or those at risk due to genetic predispositions.

Not a fit: Patients without any history of shoulder injuries or genetic predispositions to rotator cuff tears may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved prevention and treatment options for patients suffering from rotator cuff tears.

How similar studies have performed: While genetic epidemiology is a growing field, this specific investigation into rotator cuff tears is relatively novel and has not been extensively studied.

Where this research is happening

Ann Arbor, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.