Condition
Frozen Shoulder clinical trials and research
As of November 12, 2026, Find a Trial lists 20 Frozen Shoulder clinical trials that are recruiting, at sites in 11 countries (most in Turkey (Türkiye) (7), Belgium (2), Taiwan (2)). By phase: Phase 4 (3). The most active sponsors are Konya Beyhekim Training and Research Hospital (2), Shin Kong Wu Ho-Su Memorial Hospital (2). There are also 3 NIH-funded research projects on Frozen Shoulder, with $2.1 million in listed awards. Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 20Clinical trials
- 3NIH research projects
- 11Countries
Newest Frozen Shoulder clinical trials
All recruiting trials (20)
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Spinal and Kaltenborn mobilization for a stiff shoulder (frozen shoulder)
A randomized trial tests spinal mobilization with arm movement and Kaltenborn mobilization to see if they reduce pain and improve motion and function in people with adhesive capsulitis.
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Shoulder Frozen Shoulder: TAME vs Corticosteroid Injection
This study tests whether transcatheter arterial microembolization (TAME) works better than corticosteroid injections for people with frozen shoulder.
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Combined Mulligan Mobilization, Pain Neuroscience Education, and Core Stabilization for Frozen Shoulder
This study tests whether a rehab program with Mulligan mobilization, pain education, and core stabilization helps people with frozen shoulder more than standard physical therapy.
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Ultrasound-Guided PENG Block for Chronic Shoulder Pain
This study tests whether an ultrasound-guided Pericapsular Nerve Group (PENG) block can improve pain and function in adults with chronic shoulder pain who haven’t responded to standard treatments.
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Cross Training for Frozen Shoulder: Seeing if Unilateral Resistance Helps One Arm
This study tests whether unilateral resistance exercises, done without loading the affected shoulder, can improve strength and arm function in people with frozen shoulder.
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Electrophysiologic effects of 360° capsular release for frozen shoulder
We will test whether arthroscopic 360° capsular release causes measurable changes in axillary and musculocutaneous nerve function in adults (21–70) with frozen shoulder who haven't improved with conservative care.
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Comparing different NSAIDs plus home exercises for frozen shoulder
This will test whether taking one of several NSAIDs (diclofenac, meloxicam, or indomethacin) together with home shoulder exercises helps adults aged 18–75 with frozen shoulder and whether pain type changes the benefit.
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Ultrasound-guided shoulder injections for frozen shoulder
This tests whether adding ultrasound-guided suprascapular nerve block, with or without a subacromial injection, to a home exercise program reduces pain and improves shoulder function in adults with chronic frozen shoulder.
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Gluteal versus ultrasound-guided corticosteroid injections for frozen shoulder
This test will see if a buttock (gluteal) injection of compound betamethasone works as well as an ultrasound-guided steroid injection into the shoulder joint for adults 18–65 with frozen shoulder.
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Noninvasive vagus nerve stimulation plus exercises for frozen shoulder
This test will see if adding noninvasive vagus nerve stimulation to a 6‑week exercise program helps adults with frozen shoulder reduce pain, improve shoulder movement, and feel better psychologically.
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Nexsphere-F arterial embolization for chronic frozen shoulder pain
We will try a minimally invasive arterial embolization using Nexsphere-F to reduce pain in adults with frozen shoulder that hasn’t improved with usual care.
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Hormone Replacement Therapy added to standard care for frozen shoulder in peri- or postmenopausal women
This study tests whether adding hormone replacement therapy to standard treatment helps reduce pain and stiffness from frozen shoulder in peri- or postmenopausal women.
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High-intensity interval training for persistent inflammatory shoulder pain
This study will try short sessions of high-intensity interval training (HIIT) in adults with long-term shoulder pain thought to be driven by low-grade inflammation to see if the exercise is acceptable and whether inflammation and pain-related measures change.
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Using virtual reality to help rehabilitate shoulder injuries
This study tests whether using virtual reality can make shoulder rehabilitation more engaging and effective for people with shoulder injuries.
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Comparing treatments for frozen shoulder
This study is testing which of three treatments for frozen shoulder—High-Intensity Laser Therapy, corticosteroid injections, or manual therapy—works best when combined with exercise to help reduce pain and improve shoulder movement.
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Evaluating non-invasive neurostimulation for frozen shoulder treatment
This study is testing if a new non-invasive treatment using brain stimulation and tendon vibration can help people with frozen shoulder feel better compared to a placebo.
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Treatment options for managing frozen shoulder symptoms
This study is testing different treatments for frozen shoulder to see which one helps reduce pain and improve movement the most.
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Adding shock wave therapy to physiotherapy and corticosteroid injection for frozen shoulder
This study is testing if adding shock wave therapy to regular treatments for frozen shoulder can help people feel better and move their shoulder more easily.
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Treatment for Frozen Shoulder using Corticosteroid Injection and Nerve Block
This study is testing whether a combination of a corticosteroid injection and a nerve block can help people with Frozen Shoulder feel less pain and move their shoulder better compared to a fake treatment.
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Evaluating physical therapy and steroid injections for frozen shoulder treatment
This study is testing whether combining physical therapy with steroid injections helps people with frozen shoulder feel better compared to just getting steroid injections and waiting to see what happens.
NIH-funded research (3)
Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.
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Sustained Release Relaxin-2 to Treat Frozen Shoulder
A new protein therapy using extended-release relaxin-2 is explored to help people with frozen shoulder regain movement and reduce pain.
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Using Relaxin-2 to Treat Frozen Shoulder
This study is testing a new way to help people with frozen shoulder by using a hormone called relaxin-2 to ease pain and improve movement, and it could offer better long-lasting relief than the treatments currently available.
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Using relaxin to treat frozen shoulder
This study is testing a new injection treatment for frozen shoulder that uses a natural hormone to help ease pain and stiffness, aiming to improve your shoulder movement and overall quality of life.
Related topics
Quick answers
How many Frozen Shoulder clinical trials are recruiting right now?
20, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
In 11 countries. The most sites are in Turkey (Türkiye) (7 trials), Belgium (2 trials), Taiwan (2 trials), United States (2 trials), Pakistan (1 trial). Each study page lists its sites and which ones are recruiting.
What phases are they in?
Phase 4: 3. Trials with no phase listed are usually device, behavioural or observational studies.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.