Condition

Psychological clinical trials and research

• 10Clinical trials
• 133NIH research projects
• 6Countries

Newest Psychological clinical trials

All recruiting trials (10)

• Mindfulness for Emotional Distress: An EEG-Based Trial in Adults

  A randomized trial tests a mindfulness program for adults with subclinical emotional distress to see if it reduces anxiety and changes brain activity compared with progressive muscle relaxation.

  Recruiting Peking University · Beijing, Beijing Municipality · NCT07692269

• ExoBDNF probiotic to help thinking, sleep, and mood

  This study will test whether taking one daily capsule of ExoBDNF probiotic for 8 weeks can help adults 18+ improve cognition, sleep quality, or mood symptoms.

  Recruiting SunWay Biotech Co., LTD. · Taipei · NCT06968299

• Effects of exercise and brain stimulation on anxiety

  This study is testing whether combining cycling exercise with a special brain stimulation can help reduce anxiety in healthy adults.

  Recruiting Virginia Commonwealth University · Richmond, Virginia · NCT06874595

• WhatsApp-based intervention for pregnant women and their partners to improve psychological well-being and sleep quality

  This study is testing a WhatsApp program designed to help pregnant women and their partners improve their mental health and sleep quality.

  Recruiting Chinese University of Hong Kong · Hong Kong · NCT06768190

• Park-based youth physical activity program for health promotion

  This study is testing a fun afterschool program in parks that includes sports and nutrition lessons to see if it helps kids aged 6-14 get fitter and feel better mentally.

  Recruiting Duke University · Miami, Florida · NCT06595251

• Smartphone training for caregivers of Alzheimer's patients

  This study tests whether smartphone training can help caregivers of Alzheimer's patients manage stress and improve their emotional well-being.

  Recruiting William Marsh Rice University · Houston, Texas · NCT05949047

• Effects of multi-psycho-oncology care courses for oncology nurses

  This study tests whether remote relaxation and meditation courses can help stressed oncology nurses feel better so they can better support their cancer patients.

  Recruiting National Taiwan University Hospital · Taipei · NCT05776680

• Evaluating the effects of expressive writing on body image after breast cancer surgery

  This study is testing if expressive writing can help improve body image and mental health for people recovering from breast cancer surgery compared to standard care.

  Recruiting University of Roma La Sapienza · Rome, Rome · NCT05616988

• Group skills training for youth at risk of psychosis

  This study is trying out a group program that teaches important skills to help teens and young adults at risk of psychosis feel better and manage their stress.

  Recruiting University of Pittsburgh · Pittsburgh, Pennsylvania · NCT05398120

• Psychological treatment for cognitive impairment support

  This study is testing a new psychological treatment to help people with mild cognitive issues feel better and improve their daily lives.

  Recruiting Karolinska Institutet · Stockholm, Stockholm County · NCT04356924

NIH-funded research (newest 40 of 133)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Mobile app to help family caregivers in Thailand manage distress

  A mobile app called CAMMA would help family members caring for adults with chronic illnesses in Thailand feel less depressed and anxious through a culturally tailored mental health support program.

  NIH research Brigham and Women's Hospital · Boston, United States · NIH-11580924

• SPOT: A brief measure to understand wellbeing for people with dementia and their caregivers

  A new quick set of questions will help doctors and researchers understand the social and emotional wellbeing of people with dementia and their caregivers.

  NIH research University of Pennsylvania · Philadelphia, United States · NIH-11447968

• A Tablet-Based Emotion Regulation Program for Surrogate Decision-Makers of ICU Patients on Ventilation

  A randomized trial tests a brief tablet program to help people who decide for ICU patients on ventilation feel less anxious and make better decisions.

  NIH research Case Western Reserve University · Cleveland, United States · NIH-11431767

• KINDER: A new approach to help family caregivers prevent psychological elder abuse in dementia care

  A study tests a caregiver-focused program designed to reduce psychological abuse by family members caring for someone with Alzheimer’s or related dementias.

  NIH research Case Western Reserve University · Cleveland, United States · NIH-11416728

• Environmental and psychological stressors shaping anxiety, depression, and alcohol-related health issues in people with HIV

  A patient-facing overview of how stress, mental health, and alcohol use interact with HIV to influence health and aging in people living with HIV.

  NIH research Lsu Health Sciences Center · New Orleans, United States · NIH-11416371

• A mental health support program integrated into HIV care for Kenyan adolescents and young people

  A new program uses a brief, flexible mental health approach delivered by trained lay health workers to help Kenyan adolescents and young people with HIV manage depression, anxiety, and trauma alongside their HIV care.

  NIH research University of Nairobi · Nairobi, Kenya · NIH-11415601

• Psychological factors, quality of life, community, and brain aging in American Indians

  This research looks at how stress, mood, and community ties affect brain aging and risk of dementia in American Indian adults.

  NIH research Boston University Medical Campus · Boston, United States · NIH-11413437

• Adaptive psychological support to reduce opioid use after injury

  A flexible, patient-friendly program helps adults recovering from an injury use fewer opioids by offering a brief online education and mindfulness activity, followed by more in-depth sessions if needed.

  NIH research Henry Ford Health + Michigan State University Health Sciences · East Lansing, United States · NIH-11402576

• When pay is unstable: effects on stress, blood pressure, and cellular aging

  This project changes how and when low-income adults in southwestern Bangladesh get paid to learn whether unpredictable income raises stress, worsens mood, and harms physical health.

  NIH research Cornell University · Ithaca, United States · NIH-11398357

• How unpredictable pay affects stress and long-term health

  This project tests whether unpredictable, unstable income harms the mental and physical health of low-income adults in southwestern Bangladesh.

  NIH research Cornell University · Ithaca, United States · NIH-11398356

• How income ups and downs affect stress, blood pressure, and cellular aging

  Researchers will change the timing and predictability of pay for low-income workers in southwestern Bangladesh to see how unstable income affects mood, stress hormones, blood pressure, and signs of cellular aging.

  NIH research Cornell University · Ithaca, United States · NIH-11398355

• Helping autistic teens leaving high school gain everyday living skills and better quality of life

  This project tries new ways to strengthen psychological skills and service supports so autistic teens leaving high school can build everyday living skills and have a better quality of life.

  NIH research Children's Hosp of Philadelphia · Philadelphia, United States · NIH-11394314

• Biometrically personalized AI-driven music to calm dementia symptoms

  An AI-powered music program automatically creates personalized playlists to help reduce agitation, anxiety, and mood problems in adults living with dementia, without needing a clinician to guide it.

  NIH research Rubato, INC. · Pacific Palisades, United States · NIH-11393881

• Caregiver Mental Health Mobile App (CAMMA) for family caregivers of adults with chronic disorders

  A mobile app in Thailand aims to support family caregivers of adults with chronic conditions by reducing depression and anxiety through an evidence-based mental health program.

  NIH research Brigham and Women's Hospital · Boston, United States · NIH-11384734

• Phone app to spot and support emotional distress in family caregivers

  Researchers are creating a Thai-language phone app to help family members who care for adults with chronic illnesses notice early stress and get brief mental-health support.

  NIH research Brigham and Women's Hospital · Boston, United States · NIH-11379719

• Neural brain changes linked to maternal mood and infant adjustment

  A study at Yale will look at how a mother's depressive symptoms and attachment style may change her brain and caregiving, and how that affects her infant's development.

  NIH research Yale University · New Haven, United States · NIH-11376540

• Enhanced Psychological Support Navigator for Orthopedic Pain

  A short program in orthopedic clinics aims to help people with high impact chronic pain by connecting them to simple mental-health resources and coaching, right in the care setting.

  NIH research Duke University · Durham, United States · NIH-11371312

• Including informal caregivers in a video-based meditation to ease distress for breast cancer survivors

  A caregiver-inclusive online compassion-meditation program is being tested to help breast cancer survivors feel less anxiety and depression.

  NIH research University of Arizona · Tucson, United States · NIH-11370888

• A new behavioral program to boost activity after a heart event

  A new program uses friendly telephone coaching to help people recover after a heart attack by being more active and feeling more hopeful.

  NIH research Massachusetts General Hospital · Boston, United States · NIH-11370580

• Coping skills program to help COPD patients and caregivers feel better together

  A COPD-focused program tests whether teaching coping skills to patients and their caregivers reduces stress, anxiety, and distress over 12 weekly remote sessions.

  NIH research University of Pennsylvania · Philadelphia, United States · NIH-11370552

• Integrated therapy for PTSD in cardiac patients

  A brief, patient-friendly plan to help people who’ve had a serious heart event and now experience PTSD symptoms through an evidence-based, streamlined therapy.

  NIH research University of California Los Angeles · Los Angeles, United States · NIH-11369407

• Smartwatches and heart health in atrial fibrillation: how anxiety affects care use

  A trial in adults with atrial fibrillation will test whether watching wearable heart data triggers anxiety that changes how often people seek medical care.

  NIH research Univ of North Carolina Chapel Hill · Chapel Hill, United States · NIH-11366704

• Compassion-centered chaplain support to boost team safety in cancer care

  A chaplain-led program tests whether compassionate, mindfulness-based care can make oncology teams feel safer, more connected, and better able to support both providers and patients.

  NIH research Emory University · Atlanta, United States · NIH-11362465

• Role of epithelial ROS signaling in stress-related gut dysfunction and colitis risk

  This NIH grant looks at how stress changes the gut lining and its microbes, possibly increasing the risk of inflammatory bowel disease in people who are genetically predisposed.

  NIH research University of Illinois at Urbana-Champaign · Champaign, United States · NIH-11361588

• Wise social psychology ideas to boost weight-control in kids with obesity

  Two small, friendly online-like ideas (growth mindset and self-affirmation) are added to a family-based weight-control program for children ages 10–15 to see if it helps keep BMI on a healthier path over a year.

  NIH research Stanford University · Stanford, United States · NIH-11352633

• Mindfulness app to support youth in the legal system

  A multi-site, youth-focused trial tests a mindfulness meditation smartphone app to boost wellbeing and reduce distress for young people on probation.

  NIH research University of Illinois at Chicago · Chicago, UNITED STATES · NIH-11349688

• A tool to help families of ICU patients stay calm and make better decisions

  A brief, tablet-based program helps surrogate decision-makers in the ICU manage emotions and make clearer treatment choices.

  NIH research Case Western Reserve University · Cleveland, United States · NIH-11345828

• A new behavioral program to boost physical activity for adults with type 2 diabetes

  A patient-friendly program uses positive psychology and motivational interviewing to help adults with type 2 diabetes become more physically active.

  NIH research Massachusetts General Hospital · Boston, United States · NIH-11337490

• Acceptance and Commitment Therapy to boost resilience and function after stem cell transplant

  A patient-facing program tests whether Acceptance and Commitment Therapy helps people who had an allogeneic stem cell transplant feel better and stay more active.

  NIH research University of Kansas Medical Center · Kansas City, United States · NIH-11337293

• Pubertal and Psychological Development in Girls with ASD

  A study following girls with autism as they go through puberty to understand how puberty timing affects their mental and physical health.

  NIH research Vanderbilt University Medical Center · Nashville, United States · NIH-11330537

• How COVID-19 affects thinking, mental health, and social connections in recently housed veterans

  This project looks at whether having COVID-19 leads to lasting problems with memory, mood, and social connection for veterans who were recently homeless.

  NIH research VA Greater Los Angeles Healthcare System · Los Angeles, United States · NIH-11327294

• Adaptive symptom self-management to ease distress for cancer survivors on immune checkpoint inhibitors

  A study tests a phone-based symptom-monitoring program, with tailored support, to help cancer survivors on immune checkpoint inhibitors feel less distressed and manage side effects.

  NIH research University of Arizona · Tucson, United States · NIH-11326259

• Heart-rate biofeedback and coping skills to help teens with IBD feel less stressed

  This program teaches teens and young adults with Crohn's disease or ulcerative colitis breathing and heart‑rate biofeedback skills to lower stress, improve mood, and support gut health.

  NIH research Emory University · Atlanta, United States · NIH-11324588

• Mobile self-directed coping program to ease depression, anxiety, and PTSD after serious heart or lung failure

  A self-guided smartphone program that teaches adaptive coping skills to help adults recovering from ARDS, COVID pneumonia, sepsis, or heart failure feel less depression, anxiety, and PTSD.

  NIH research Duke University · Durham, United States · NIH-11324520

• Managing symptoms and distress for people taking oral anti-cancer drugs

  A new program tests a 12-week automated phone symptom check-in plus an optional 8-week counseling add-on to help reduce fatigue, mood symptoms, and other side effects for cancer survivors on oral medications.

  NIH research Michigan State University · East Lansing, United States · NIH-11312625

• Social connections, family life, and Huntington’s disease progression in parents and their kids

  A study explores how social relationships and communication between people with Huntington’s disease and their children affect well-being and disease progression.

  NIH research Vanderbilt University · Nashville, UNITED STATES · NIH-11294175

• Blueprint mobile self-help program to ease stress after heart or lung failure

  This project offers a self-guided smartphone app that teaches coping skills to help people recovering from serious heart or lung failure reduce depression, anxiety, and PTSD symptoms.

  NIH research Oregon Health & Science University · Portland, United States · NIH-11292410

• Long-term stress and heart health in frontline emergency workers after COVID-19

  This project looks at whether lasting anxiety, stress, and sleep problems in emergency department healthcare workers after COVID-19 affect their future heart health.

  NIH research Columbia University Health Sciences · New York, United States · NIH-11290732

• Social and psychological factors behind Black adults’ smoking gaps

  This project looks at why Black adults who smoke have more trouble quitting and what social and psychological factors influence quitting, with the goal of creating tailored cessation support.

  NIH research City College of New York · New York, United States · NIH-11285697

• How neighborhood problems and social stress affect chronic pain in older adults

  This project looks at whether problems in the places people live and difficult social relationships make chronic pain worse for older adults.

  NIH research University of Florida · Gainesville, United States · NIH-11285148

Related topics

Quick answers

How many Psychological clinical trials are recruiting right now?

10, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 6 countries. The most sites are in United States (4 trials), Taiwan (2 trials), Hong Kong (1 trial), China (1 trial), Italy (1 trial). Each study page lists its sites and which ones are recruiting.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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