NIH-funded research R01 grant

Pubertal and Psychological Development in Girls with ASD

Official title: Pubertal, Psychological and Physiological Development in Females with Autism

Funded at Vanderbilt University Medical Center · NIH-11330537 · Data updated 2026-11-12

A study following girls with autism as they go through puberty to understand how puberty timing affects their mental and physical health.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionVanderbilt University Medical Center
NIH-funded
Lab location1 site (Nashville, United States)
Project startSeptember 1, 2022
Project endJune 30, 2027
Funding year2026
Award (this year)$450,424
NIH project number5R01HD107695-05
Project IDNIH-11330537 on NIH RePORTER

Who could benefit from this research

Could help

Girls around the onset of puberty who have been diagnosed with autism spectrum disorder.

Less likely to help

Prepubertal girls without ASD or post-pubertal individuals may not benefit from these findings.

What this research studies

This project looks at how puberty starts and progresses in girls with autism and how these changes relate to mood, stress, and social interaction. Researchers will use real-world assessments of pubertal development, behavior, and brain-related processing to track changes over time. The goal is to identify patterns that may explain why puberty can be particularly challenging for females with ASD and to inform better support strategies. The findings could help families and clinicians anticipate needs and tailor interventions during this critical developmental period.

Why it matters

Potential benefit: It could lead to better guidance and support for girls with ASD during puberty, improving mental health and well-being.

How similar studies have gone: Prior research has identified differences in pubertal timing and stress responses in ASD, suggesting this approach could yield actionable insights.

Where this research is happening

  • Vanderbilt University Medical Center
    Nashville, United States
    Active

Researchers

  • Principal investigator: Corbett, Blythe Anne — Vanderbilt University Medical Center
  • Study coordinator: Corbett, Blythe Anne

Related research

Other NIH-funded projects on the same topics.

  • Puberty and Development in Girls with Autism

    This project explores how puberty affects girls with autism, including their physical, emotional, and social changes.

    NIH research Vanderbilt University Medical Center · Nashville, United States · NIH-11120843

  • Understanding puberty and its effects on girls with autism

    This study looks at how puberty affects girls with autism, exploring the changes they go through and the unique challenges they face, so we can better support their well-being during this important time.

    NIH research Vanderbilt University Medical Center · Nashville, United States · NIH-10864816

  • Neural roots of how autistic adults understand word meaning

    A study to understand how adults with autism process word meanings in the brain, aiming to improve language support.

    NIH research Ut Southwestern Medical Center · Dallas, United States · NIH-11640092

  • Sleep and daily rhythms and brain development in autism

    Aiming to understand how sleep problems and daily activity patterns affect brain growth, thinking skills, daily functioning, and autism symptoms in children.

    NIH research Hugo W. Moser Res Inst Kennedy Krieger · Baltimore, United States · NIH-11597098

  • Early sensory development and language in infants/toddlers at risk for autism

    A family-friendly study exploring how early sensory responses relate to language development in young children who have siblings with autism.

    NIH research University of Hawaii at Manoa · Honolulu, United States · NIH-11594304

  • Mobile app to help family caregivers in Thailand manage distress

    A mobile app called CAMMA would help family members caring for adults with chronic illnesses in Thailand feel less depressed and anxious through a culturally tailored mental health support program.

    NIH research Brigham and Women's Hospital · Boston, United States · NIH-11580924

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.