NIH-funded research R01 grant

A mental health support program integrated into HIV care for Kenyan adolescents and young people

Official title: INTEGRATING A TRANSDIAGNOSTIC PSYCHOLOGICAL INTERVENTION IN THE CARE FOR ADOLESCENTS AND YOUTH WITH HIV IN KENYA

Funded at University of Nairobi · NIH-11415601 · Data updated 2026-11-12

A new program uses a brief, flexible mental health approach delivered by trained lay health workers to help Kenyan adolescents and young people with HIV manage depression, anxiety, and trauma alongside their HIV care.

More Psychological research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Nairobi
NIH-funded
Lab location1 site (Nairobi, Kenya)
Project startAugust 1, 2023
Project endMay 31, 2028
Funding year2026
Award (this year)$497,628
NIH project number5R01MH133261-04
Project IDNIH-11415601 on NIH RePORTER

Who could benefit from this research

Could help

Ideal participants are adolescents and young people with HIV in Kenya who have mild to moderate depression or anxiety and can receive care within or alongside HIV clinics.

Less likely to help

Patients with severe mental illness or those unable to access HIV care clinics may not benefit from this approach.

What this research studies

This grant tests a transdiagnostic CBT-based intervention (PRO-ACT) that can be delivered in person or by phone to AYHIV in Kenya, aiming to fit real-world HIV care settings. It builds on a successful pilot and focuses on adapting the approach to the local HIV care context, including how many sessions are practical. The study seeks to show whether integrating mental health support within HIV clinics can improve mental health symptoms and HIV treatment outcomes. The delivery relies on lay health workers rather than specialists to broaden access in resource-limited settings.

Why it matters

Potential benefit: If successful, the program could improve mental health and HIV treatment outcomes for AYHIV by integrating care into routine HIV services.

How similar studies have gone: Previous pilot results showed symptom reductions with a brief modular intervention, suggesting potential for broader impact.

Where this research is happening

  • University of Nairobi
    Nairobi, Kenya
    Active

Researchers

  • Principal investigator: Wamalwa, Dalton Chekoko — University of Nairobi
  • Study coordinator: Wamalwa, Dalton Chekoko

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.