Psychological treatment for cognitive impairment support

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study focuses on providing psychological treatment to individuals experiencing cognitive impairment, specifically those with subjective cognitive decline (SCD) and mild cognitive impairment (MCI). The intervention is based on a novel treatment manual that incorporates cognitive behavioral therapy (CBT) principles, adapted to meet the needs of cognitively affected individuals. The approach aims to facilitate behavioral changes aligned with personal values and long-term goals, while addressing associated psychological symptoms such as anxiety and depression. Participants will receive support through reminders and tailored sessions to enhance their daily functioning and quality of life.

Why it matters

Who can join: the full rules

* Criteria's for inclusion
* \< 75 years.
* SCD or MCI diagnosis. All cognitive MCI-subtypes are eligible.
* Mild to moderate psychological symptoms that are indicated to be related to the patient's CI. The psychological symptoms should affect the patients daily living and behavior, exemplified by avoidance behavior, social anxiety and perceived stigmatization.
* Fluency in the Swedish language.
* The patients should have access to a mobile telephone to be able to receive reminders via Short Message Service (SMS).
* Signed informed consent.
* Criteria's for exclusion
* Dementia diagnosis and/or occurrence of serious illness and/or injury that requires immediate investigation or treatment of another type, or which is expected to worsen in the coming year (i.e., not including dementia)
* Severe psychiatric comorbidity (e.g., high suicide risk), and/or severe psychiatric disorder. This will be assessed in the MINI evaluation and during the clinical cognitive examination).
* Anti-depressant medication introduced or alterations in dosage \< 6 months ago (i.e., un-stable dose).
* Mini Mental State Examination (MMSE) score \< 26 and/or a Montreal Cognitive Assessment (MoCA) score \< 24.
* Stroke or head trauma \< 6 months ago.
* Substance abuse

Where it's running

• Karolinska University Hospital
  Stockholm, Stockholm County, Sweden Recruiting

Study contacts

• Study coordinator: Urban Ekman, PhD
• Email: urban.ekman@ki.se
• Phone: +468-517 713 66

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.