Condition

Prostatectomy clinical trials and research

• 10Clinical trials
• 17NIH research projects
• 1New in 30 days
• 8Countries

Newest Prostatectomy clinical trials

All recruiting trials (10)

• Pain management plan implementation for major open abdominal surgeries

  This trial tests an opioid-epidural pain management approach to see if it improves post-surgical pain control for adults undergoing open abdominal procedures like colectomy, hepatectomy, and nephrectomy.

  Recruiting National and Kapodistrian University of Athens · Athens, Athens · NCT07901582

• Nerve-Sparing Robotic Prostatectomy: How Baseline Health Affects Post-Surgery Erections

  Researchers will test whether a patient’s age, health history, and pre-surgery sexual function can predict erectile function after nerve-sparing robot-assisted prostatectomy.

  Recruiting University of Florence · Florence, Italy · NCT07747272

• Testing two RARP training methods with a hydrogel model

  This randomized study tests whether a training pathway using a hydrogel prostatectomy model can match the standard training pathway for learning robot-assisted radical prostatectomy.

  Recruiting Orsi Academy · Melle, Belgium · NCT07669974

• Comparison of radical prostatectomy and precision prostatectomy for men with low- or intermediate-risk prostate cancer

  This trial tests whether precision prostatectomy preserves sexual function and bladder control better than radical prostatectomy for men with low- or intermediate-risk prostate cancer.

  Recruiting Henry Ford Health System · Detroit, Michigan · NCT07348367

• High Dose Rate Brachytherapy for Prostate Cancer Recurrence

  This study is testing if a special type of radiation treatment called High Dose Rate Brachytherapy can help men with prostate cancer that has come back after surgery feel better and have fewer side effects compared to regular radiation.

  Recruiting Clinica Universidad de Navarra, Universidad de Navarra · Pamplona, Foral Community of Navarre · NCT06982469

• Telemedicine-guided prehabilitation to reduce urinary incontinence after prostatectomy

  In men planning radical prostatectomy for localized prostate cancer, this study tests a telemedicine-supported prehabilitation and rehabilitation program to see if it lowers postoperative urinary incontinence.

  Recruiting University Hospital Olomouc · Olomouc · NCT06981026

• Robotic Prostatectomy Pain Reduction with Two Insufflation Devices

  This trial tests whether two different pneumoperitoneum devices used during robotic prostatectomy affect pain after surgery in men with prostate cancer.

  Recruiting East and North Hertfordshire NHS Trust · Stevenage, Hertfordshire · NCT06915909

• Using HIFEM technology to treat urinary incontinence in men after prostate surgery

  This study is testing if a new HIFEM treatment can help men who have had prostate surgery with their urinary incontinence better than standard care.

  Recruiting Chinese University of Hong Kong · Shatin · NCT06589869

• Treatment for male overactive bladder using sacral neuromodulation

  This study is testing a new device to see if it can help men with overactive bladder feel better after prostate surgery or radiation therapy.

  Recruiting at 21 sites Axonics, Inc. · Birmingham, Alabama and 22 other locations · NCT06511141

• Personalized treatment for prostate cancer to improve quality of life after surgery

  This study is testing whether a personalized treatment using apalutamide can help improve the quality of life and reduce fatigue for prostate cancer patients with detectable PSA levels after surgery, compared to standard therapy.

  Recruiting at 6 sites Phase 3 M.D. Anderson Cancer Center · Gilbert, Arizona and 5 other locations · NCT06274047

NIH-funded research (17)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• New Diaphragm-like implant to prevent urinary leakage after prostate cancer surgery

  A resorbable implant placed at the time of prostate cancer surgery helps men regain bladder control faster and reduces the need for pads or secondary procedures.

  NIH research Levee Medical INC · Raleigh, United States · NIH-11409594

• Pelvic fascia-sparing radical prostatectomy: a better-path to fewer side effects

  A large research project tests a new surgical approach for prostate cancer that may reduce urinary leakage and erectile problems after surgery.

  NIH research Weill Medical Coll of Cornell Univ · New York, United States · NIH-11390967

• Preserving Erectile Function during Robotic Prostate Surgery by Measuring Nerve-Sparing Technique

  Aims to create an objective way to measure how well surgeons perform the nerve-sparing part of robot-assisted prostate cancer surgery to help patients keep erectile function.

  NIH research Cedars-Sinai Medical Center · Los Angeles, United States · NIH-11360678

• Tools that light up cancer and nerves during prostate removal

  This project develops cameras and safe fluorescent dyes to show prostate cancer margins and nearby nerves in real time during prostate removal surgery for men with prostate cancer.

  NIH research Oregon Health & Science University · Portland, United States · NIH-11307146

• PSMA-PET imaging to guide prostate removal and protect nerves

  This will see if a PSMA-PET scan using the 68Ga-P16-093 tracer can help surgeons choose nerve- and muscle-sparing surgery versus wider removal for men having prostatectomy for prostate cancer.

  NIH research Indiana University Indianapolis · Indianapolis, United States · NIH-11294367

• Pelvic fascia-sparing prostate surgery

  This research compares a pelvic fascia-sparing prostate removal to standard prostate surgery to try to lower long-term urinary and sexual side effects for men with localized prostate cancer.

  NIH research Weill Medical Coll of Cornell Univ · New York, United States · NIH-11191706

• Using yoga to help veterans with prostate cancer manage side effects after surgery

  This study is looking at how a special yoga program can help veterans who have had prostate cancer surgery feel better by easing issues like erectile dysfunction and urinary problems, and it’s designed to support their mental health too, with sessions available both in-person and online.

  NIH research Edward Hines Jr VA Hospital · Hines, United States · NIH-11140994

• A telomere test to guide aggressive treatment after rising PSA following prostate surgery

  This project looks at whether a lab test that measures telomere patterns in prostate tissue can help doctors choose which men with rising PSA after prostate removal should get added hormone therapy with salvage radiation.

  NIH research Johns Hopkins University · Baltimore, United States · NIH-11136865

• Improving Erectile Function After Prostate Cancer Surgery

  This project aims to help surgeons better protect nerves during prostate cancer surgery, which can lead to better recovery of erectile function for patients.

  NIH research Cedars-Sinai Medical Center · Los Angeles, United States · NIH-11123096

• New tools for better cancer surgery that help see nerves and cancer at the same time

  This study is working on new tools to help surgeons see both cancer and important nerves during prostate cancer surgery, which could lead to better results and fewer side effects like incontinence and impotence for patients.

  NIH research Oregon Health & Science University · Portland, United States · NIH-11070400

• Using PSMA-PET imaging to improve prostate cancer surgery outcomes

  This study is looking at a new imaging method called PSMA-PET to help doctors plan better surgeries for men with prostate cancer by showing how far the cancer has spread, which could lead to better results and a happier recovery for patients.

  NIH research Indiana University Indianapolis · Indianapolis, United States · NIH-11038037

• Improving nerve-sparing surgery for prostate cancer using advanced imaging techniques

  This study is testing a new imaging technique to help surgeons better identify cancer during prostate surgery, which could lead to more men being able to keep their nerves intact and improve their recovery of sexual function and bladder control after the operation.

  NIH research Massachusetts Institute of Technology · Cambridge, United States · NIH-11014968

• A new surgical technique to reduce side effects of prostate cancer surgery

  This study is looking at a new type of prostate cancer surgery that aims to reduce long-term side effects like urinary incontinence and erectile dysfunction, and it's for men who are considering surgery for prostate cancer.

  NIH research Weill Medical Coll of Cornell Univ · New York, United States · NIH-10925145

• Using telomere length to guide treatment decisions for men with rising PSA after prostate surgery

  This study is looking at how the length of telomeres in your cells can help doctors predict which men might need more intense treatment after prostate surgery if their cancer comes back, so they can make better choices about care for 839 men.

  NIH research Johns Hopkins University · Baltimore, United States · NIH-10911785

• Improving erectile function recovery after prostate cancer surgery

  This study is looking at ways to help men recover better erectile function after surgery for prostate cancer by teaching surgeons better techniques through video analysis and virtual reality training.

  NIH research Cedars-Sinai Medical Center · Los Angeles, United States · NIH-10862724

• Improving nerve visibility during prostate surgery

  This study is testing a new dye that helps surgeons see nerves better during prostate surgery, which could help prevent problems like incontinence and impotence, making the surgery safer for patients.

  NIH research Oregon Health & Science University · Portland, United States · NIH-10832516

• Using special dyes to help surgeons see nerves during prostate surgery

  This study is testing a special dye that helps surgeons see and protect nerve tissues during prostate surgery, aiming to improve recovery and reduce the chances of nerve damage for patients.

  NIH research Trace Biosciences INC · Beaverton, UNITED STATES · NIH-10651903

Related topics

Quick answers

How many Prostatectomy clinical trials are recruiting right now?

10, as of November 12, 2026. 1 of them was first registered in the last 30 days. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 8 countries. The most sites are in United States (3 trials), Czechia (1 trial), Italy (1 trial), Hong Kong (1 trial), United Kingdom (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 3: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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