Clinical trial Recruiting at 1 site Interventional Ages 18 to 80

Pain management plan implementation for major open abdominal surgeries

Official title: Implementation of a Pain Management Plan in Major Open Abdominal Surgeries.

Run by National and Kapodistrian University of Athens · NCT07901582 · Data updated 2026-11-12

This trial tests an opioid-epidural pain management approach to see if it improves post-surgical pain control for adults undergoing open abdominal procedures like colectomy, hepatectomy, and nephrectomy.

Quick facts

Study typeInterventional
Ages18 Years to 80 Years
SexAll
Enrollment58 (estimated)
SponsorNational and Kapodistrian University of Athens
Academic / other
Drugs / interventionschemotherapy
Locations1 site (Athens, Athens)
StatusRecruiting
StartedNovember 22, 2025
Main results expectedSeptember 20, 2027
Study endsNovember 2027
Registry record updatedOctober 30, 2026
Trial IDNCT07901582 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults scheduled for elective open abdominal surgeries (e.g., colectomy, pancreatohepatic or nephrectomy) without contraindications to epidural analgesia.

Probably not a fit

Patients with coagulation disorders, certain CNS demyelinating conditions, severe hemodynamic instability, or known allergy to local anesthetics may not benefit from this approach.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This interventional study focuses on tailoring postoperative analgesia for patients undergoing major open abdominal surgeries. It examines the use of epidural-administered opioids as part of a structured pain management plan to address the high pain burden after procedures such as colectomy, hepatectomy, and nephrectomy. The goal is to minimize pain while reducing complications and promoting faster recovery, taking into account individual patient factors and surgical specifics. The trial builds on prior evidence suggesting epidural analgesia can improve pain scores and recovery in abdominal surgery settings. Conducted at Evangelismos General Hospital with leadership from the National and Kapodistrian University of Athens, the study emphasizes precision analgesia in a heterogeneous surgical population.

Why it matters

Potential benefit: If successful, participants may experience better pain control and faster functional recovery after major open abdominal surgery.

How similar studies have gone: Previous research suggests epidural analgesia can reduce pain and improve outcomes after abdominal surgery, but results vary by procedure and patient factors.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

Elective surgical patients admitted for open abdominal surgeries.

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Exclusion Criteria:

Coagulation disorders. Demyelinating disorders of the CNS. Severe hemodynamic instability requiring vasopressors from the early beginning of the surgery. Reported allergic reaction to local anaesthetics Objection to take part.

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Where it's running

  • Evangelismos General Hospital
    Athens, Athens, Greece
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.