Pain management plan implementation for major open abdominal surgeries
Official title: Implementation of a Pain Management Plan in Major Open Abdominal Surgeries.
Run by National and Kapodistrian University of Athens · NCT07901582 · Data updated 2026-11-12
This trial tests an opioid-epidural pain management approach to see if it improves post-surgical pain control for adults undergoing open abdominal procedures like colectomy, hepatectomy, and nephrectomy.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 80 Years |
| Sex | All |
| Enrollment | 58 (estimated) |
| Sponsor | National and Kapodistrian University of Athens Academic / other |
| Drugs / interventions | chemotherapy |
| Locations | 1 site (Athens, Athens) |
| Status | Recruiting |
| Started | November 22, 2025 |
| Main results expected | September 20, 2027 |
| Study ends | November 2027 |
| Registry record updated | October 30, 2026 |
| Trial ID | NCT07901582 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults scheduled for elective open abdominal surgeries (e.g., colectomy, pancreatohepatic or nephrectomy) without contraindications to epidural analgesia.
✕Probably not a fit
Patients with coagulation disorders, certain CNS demyelinating conditions, severe hemodynamic instability, or known allergy to local anesthetics may not benefit from this approach.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This interventional study focuses on tailoring postoperative analgesia for patients undergoing major open abdominal surgeries. It examines the use of epidural-administered opioids as part of a structured pain management plan to address the high pain burden after procedures such as colectomy, hepatectomy, and nephrectomy. The goal is to minimize pain while reducing complications and promoting faster recovery, taking into account individual patient factors and surgical specifics. The trial builds on prior evidence suggesting epidural analgesia can improve pain scores and recovery in abdominal surgery settings. Conducted at Evangelismos General Hospital with leadership from the National and Kapodistrian University of Athens, the study emphasizes precision analgesia in a heterogeneous surgical population.
Why it matters
Potential benefit: If successful, participants may experience better pain control and faster functional recovery after major open abdominal surgery.
How similar studies have gone: Previous research suggests epidural analgesia can reduce pain and improve outcomes after abdominal surgery, but results vary by procedure and patient factors.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: Elective surgical patients admitted for open abdominal surgeries. \- Exclusion Criteria: Coagulation disorders. Demyelinating disorders of the CNS. Severe hemodynamic instability requiring vasopressors from the early beginning of the surgery. Reported allergic reaction to local anaesthetics Objection to take part. \-
Where it's running
-
Evangelismos General Hospital
Athens, Athens, Greece Recruiting
Study contacts
- Study coordinator: Maria Zachariadi, Medical Doctor
- Email: maria11095@yahoo.gr
- Phone: +35799760521
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.