Using special dyes to help surgeons see nerves during prostate surgery

Clinical Translation of Near Infrared Nerve-Specific Fluorophores for Nerve-sparing Prostatectomy

NIH-funded research Trace Biosciences INC · NIH-10651903

This study is testing a special dye that helps surgeons see and protect nerve tissues during prostate surgery, aiming to improve recovery and reduce the chances of nerve damage for patients.

Quick facts

Grant typeSbir 2 grant
Study typeNIH-funded research
Funding institutionTrace Biosciences INC NIH-funded
Lab location1 site (Beaverton, UNITED STATES)
Project IDNIH-10651903 on NIH RePORTER

What this research studies

This research focuses on improving surgical outcomes for patients undergoing radical prostatectomy by using near-infrared fluorophores that specifically label nerve tissue. The goal is to enhance the surgeon's ability to identify and preserve nerves during surgery, which can significantly reduce the risk of nerve damage. The approach involves administering a targeted dye that binds to nerve tissues, making them visible during the procedure. This innovative technique aims to minimize complications associated with nerve injuries, which can lead to long-term disability.

Who could benefit from this research

Good fit: Ideal candidates for this research are men scheduled to undergo radical prostatectomy who are concerned about the risk of nerve damage during surgery.

Not a fit: Patients who are not undergoing prostate surgery or those with conditions that contraindicate the use of fluorophores may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to safer prostate surgeries with fewer nerve injuries, improving recovery and quality of life for patients.

How similar studies have performed: Similar approaches using fluorescence-guided surgery have shown promise in other surgical fields, indicating potential success for this novel application.

Where this research is happening

Beaverton, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Cancers
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.