Pelvic fascia-sparing prostate surgery
Pelvic fascia spARing radical prostatectomy TrIAL (PARTIAL)
This research compares a pelvic fascia-sparing prostate removal to standard prostate surgery to try to lower long-term urinary and sexual side effects for men with localized prostate cancer.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Weill Medical Coll of Cornell Univ NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-11191706 on NIH RePORTER |
What this research studies
If you have localized prostate cancer and are considering prostate removal, this study randomly assigns men to a new pelvic fascia-sparing surgical approach or to the usual surgery. Doctors at multiple hospitals will follow patients for years to measure urinary control, erectile function, penile changes, hernia risk, and cancer outcomes. The team uses methods designed to enroll more patients across centers and maintain longer follow-up than prior small studies. Results will show whether the fascia-sparing approach improves quality of life without compromising cancer control.
Who could benefit from this research
Good fit: Men with localized prostate cancer who are planning radical prostatectomy and are medically eligible and willing to be randomized between surgical approaches.
Not a fit: Men with advanced or metastatic prostate cancer, those who are not surgical candidates, or those with prior pelvic radiation or surgery are unlikely to benefit from this trial.
Why it matters
Potential benefit: If successful, the fascia-sparing approach could reduce long-term urinary incontinence, erectile dysfunction, and penile changes while keeping cancer control similar to standard surgery.
How similar studies have performed: Several small retrospective series have reported notably better urinary and sexual outcomes with pelvic fascia-sparing surgery, but large randomized trials with long-term oncologic follow-up have not yet been done.
Where this research is happening
New York, United States
- Weill Medical Coll of Cornell Univ — New York, United States (Active)
Researchers
- Principal investigator: Hu, Jim — Weill Medical Coll of Cornell Univ
- Study coordinator: Hu, Jim
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.