Improving maternal and newborn health care access

Pregnancy Risk, Infant Surveillance, and Measurement Alliance (PRiSMA) Maternal and Newborn Health (MNH) Study: A Multi-center, Prospective Cohort Study of Maternal, Newborn, and Infant Health

George Washington University · NCT05904145

This study is trying to find ways to improve access to quality care for pregnant women and their newborns in low-resource areas to help them have healthier pregnancies and births.

Quick facts

Study typeObservational
Enrollment267897 (estimated)
Ages15 Years and up
SexFemale
SponsorGeorge Washington University (other)
Locations5 sites (Kintampo and 4 other locations)
Trial IDNCT05904145 on ClinicalTrials.gov

What this trial studies

This observational study focuses on enhancing access to quality antenatal and postnatal care for pregnant women and newborns in resource-poor regions. It aims to identify gaps in care delivery and assess the effectiveness of current practices in detecting risks and preparing women for childbirth. The study will involve women living within specific catchment areas in countries like Ghana, Kenya, Pakistan, Zambia, and India, who are in their first 20 weeks of pregnancy. By gathering data on maternal and newborn health services, the study seeks to inform better healthcare strategies and improve outcomes for vulnerable populations.

Who should consider this trial

Good fit: Ideal candidates for this study are pregnant women under 20 weeks of gestation who reside within the designated study areas.

Not a fit: Patients with nonviable pregnancies or those planning to relocate outside the study area during pregnancy may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved maternal and newborn health outcomes by ensuring better access to quality care.

How similar studies have performed: Other studies have shown success in improving maternal and newborn health outcomes through enhanced care access, indicating that this approach has potential.

Eligibility criteria

Show full inclusion / exclusion criteria
A woman who meets the following inclusion criteria during screening may be enrolled:

* Lives within the study catchment area;
* Meets minimum age requirement in study site country:

  * Ghana: 15 years of age;
  * Kenya: 18 years of age or those who meet the criteria of emancipated minors;
  * Pakistan: 15 years of age or those who meet the criteria of emancipated minors;
  * Zambia: 15 years of age;
  * India: 18 years of age
* Intrauterine pregnancy \<20 weeks gestation verified via ultrasound;
* Provides informed consent.

A woman who meets the following exclusion criteria during screening may NOT be enrolled:

* Nonviable (e.g. ectopic or molar) pregnancy;
* Plans to relocate outside of the study catchment area during pregnancy and/or postpartum.

Where this trial is running

Kintampo and 4 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Pregnancy, High Risk, Antenatal Care, Postnatal Care, Maternal Newborn Health

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.