MOCHA: Inpatient Mental Health Care for High-Risk Pregnancy
Official title: MOCHA Protocol: Embedded Inpatient Mental Health Care for High-Risk Perinatal Patients
Run by Indiana University · NCT07540585 · Data updated 2026-11-12
This study tests a collaborative mental health program for pregnant or recently postpartum patients hospitalized for medical problems to see if it can be delivered feasibly and acceptably.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years to 100 Years |
| Sex | Women only |
| Enrollment | 50 (estimated) |
| Sponsor | Indiana University Academic / other |
| Locations | 1 site (Indianapolis, Indiana) |
| Status | Recruiting |
| Started | July 15, 2026 |
| Main results expected | September 1, 2027 |
| Study ends | September 1, 2027 |
| Registry record updated | September 8, 2026 |
| Trial ID | NCT07540585 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults 18+ who are pregnant or recently postpartum, on a high-risk inpatient obstetric unit, with at least one adverse pregnancy outcome, and English-speaking.
✕Probably not a fit
Patients not experiencing significant mood or trauma-related symptoms or those not benefiting from brief psychotherapy may not experience measurable mental health improvements.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
Project MOCHA is a single-arm implementation study embedded in a high-risk obstetric unit to deliver early mental health screening, trauma-informed psychotherapy, and structured follow-up for three months after discharge. It aims to assess feasibility, acceptability, and fidelity of the Collaborative Mental Health Care Program in routine inpatient maternity care. Participants receive brief inpatient therapy, symptom monitoring, and post-discharge telehealth or in-person follow-up, with preliminary changes in depression, anxiety, ADHD symptoms, and PTSD evaluated to inform future trials. The program sits atop usual medical care and is conducted at Riley Maternity Tower under the Indiana University umbrella. Enrollment is limited to English-speaking adults 18+ who are pregnant or recently postpartum with at least one adverse pregnancy outcome and extended inpatient stay.
Why it matters
Potential benefit: If successful, the program could improve emotional well-being and support continuity of mental health care for high-risk obstetric patients during hospitalization and after discharge.
How similar studies have gone: Previous work in integrated maternity care models has shown promise for improving mood and follow-up, but this specific inpatient collaborative program in high-risk obstetrics is relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * 18 years old or older * Pregnant (or recently have given birth) at any gestational age * Must have experienced at least one adverse pregnancy outcome * Admitted for an extended inpatient stay * English speaking Exclusion Criteria: * Under 18 years old * Not currently pregnant or past one year postpartum * Not experienced at least one adverse pregnancy outcome * Not admitted for an extended inpatient stay at RMT
Where it's running
-
Riley Hospital for Children at Indiana University Health
Indianapolis, Indiana, United States Recruiting
Study contacts
- Principal investigator: Tiffany R Williams, PhD — Indiana University
- Study coordinator: Tiffany R Williams, PhD
- Email: tw84@iu.edu
- Phone: 317-963-7300
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
Evaluating Fertility Treatments in Women with Rheumatic Diseases
This study is trying to see how well fertility treatments work for women with rheumatic diseases and if these treatments affect their health conditions.
-
Evaluating placental markers in pregnant women with and without antiphospholipid syndrome
This study is trying to see if certain markers in the blood can help predict the risk of preeclampsia in pregnant women with antiphospholipid syndrome compared to those without it.
-
Observational study on the safety of relugolix therapy in pregnant women
This study is trying to see if relugolix therapy is safe for pregnant women and their babies by looking at health outcomes during and after pregnancy.
-
AI-assisted home-based mood diary for kids with ADHD
A home-based program uses an AI-assisted diary that turns daily mood entries into comic strips to see if it helps kids with ADHD improve emotion regulation.
-
Understanding anxiety, depression, and bipolar disorder over time in China
This study tests how anxiety, depressive, and bipolar symptoms change over three years to find patterns that help with earlier recognition and prediction in people aged 12–55.
-
See if personalized CBM-I can help anxious kids ages 10–17
Aimed at youth with Generalized, Separation, or Social Anxiety, the study tests a personalized cognitive bias modification for interpretation (CBM-I) to see if it reduces threat-focused thinking and anxiety.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.