Condition

Overweight/Obesity clinical trials and research

• 9Clinical trials
• 5Countries

Newest Overweight/Obesity clinical trials

All recruiting trials (9)

• Single-dose PK study of HRS-4729 in adults with and without kidney impairment

  This study tests a single dose of HRS-4729 to see how the body handles it in adults with various levels of kidney function compared with healthy adults.

  Recruiting Phase 1 Fujian Shengdi Pharmaceutical Co., Ltd. · Chengdu, Sichuan · NCT07807059

• TQF3250 Capsules in overweight and obese adults with limited weight loss from lifestyle changes

  This phase 1b study tests whether TQF3250 capsules are safe and tolerable, and whether they show preliminary signs of benefit, in adults with overweight or obesity who have not achieved enough weight loss with simple lifestyle changes.

  Recruiting at 6 sites Phase 1 Chia Tai Tianqing Pharmaceutical Group Co., Ltd. · Beijing, Beijing Municipality and 9 other locations · NCT07798284

• MOTS-c to improve insulin sensitivity in adults with prediabetes and overweight or obesity

  This 12-week test will see if the investigational peptide MOTS-c can improve insulin sensitivity in adults with prediabetes who are overweight or have obesity.

  Recruiting Phase 2 Hudson Biotech · Shenzhen, Guangdong · NCT07505745

• Cranberry for gut and metabolic health in adults with overweight or obesity

  This study will test whether drinking a cranberry beverage can improve blood sugar control, insulin sensitivity, blood lipids, and gut microbiota in adults with overweight or obesity who have metabolic risk factors.

  Recruiting Laval University · Québec, Quebec · NCT07460856

• How walnut versus pretzel snacks change brain responses and fullness during dieting

  This trial will test whether eating a daily walnut snack versus a pretzel snack changes brain responses to food and feelings of fullness in adults aged 25–45 with BMI ≥27 who are trying to lose weight.

  Recruiting University of Colorado, Denver · Aurora, Colorado · NCT07428187

• Effects of a Low Valine Diet on Weight and Metabolism

  This study is testing if meal replacements with less valine can help overweight and obese people lose weight and improve their metabolism compared to regular meal replacements.

  Recruiting Shanghai Zhongshan Hospital · Shanghai, Shanghai Municipality · NCT06883578

• Digital health coaching using wearable technology for chronic disease prevention

  This study is testing whether digital health coaching with wearable technology can help people at risk of chronic diseases like high blood pressure and diabetes make healthier lifestyle choices to prevent these conditions.

  Recruiting Alexandra Hospital · Singapore · NCT06752772

• Exercise and brain responses to stress-related eating in veterans

  This study tests whether adding a structured exercise program for 12 weeks changes how veterans’ brains respond to thinking tasks and food images, and whether hormonal differences between men and women influence those brain changes.

  Recruiting VA Office of Research and Development · Aurora, Colorado · NCT06627569

• Testosterone Undecanoate's effects on liver fat in overweight men with diabetes

  This study is testing if a testosterone treatment can help reduce liver fat in overweight men with type 2 diabetes and low testosterone levels.

  Recruiting Phase 4 Medical University of Vienna · Vienna · NCT03851627

Related topics

Quick answers

How many Overweight/Obesity clinical trials are recruiting right now?

9, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 5 countries. The most sites are in China (4 trials), United States (2 trials), Singapore (1 trial), Canada (1 trial), Austria (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 1: 2, Phase 2: 1, Phase 4: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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